Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              19     869
NP_653080                                                              19     869
XP_005267292                                                           19     869
XP_005267291                                                           19     869
XP_005267290                                                           19     869
NP_061961                                                              17    3301
NP_659417                                                              17    4312
NP_001273359                                                           17    4312
NP_620147                                                              17    4312
XP_006715416                                                           17    4312
XP_006715415                                                           17    4312
XP_005266895                                                           17    4312
NP_001074419                                                           16    5631
NP_001074248                                                           16    5631
NP_060193                                                              16    5631
NP_203693                                                              16    5631
XP_005256712                                                           16    5631
NP_071921                                                              16    7355
NP_596870                                                              16    7355
NP_001012398                                                           16    7355
XP_005256155                                                           16    7355
XP_005256154                                                           16    7355
XP_005256153                                                           16    7355
XP_005256152                                                           16    7355
XP_005256151                                                           16    7355
NP_001278350                                                           15    9605
NP_001278347                                                           15    9605
NP_001278346                                                           15    9605
NP_066963                                                              15    9605
NP_001278345                                                           15    9605
NP_001278344                                                           15    9605
NP_055946                                                              15    9605
NP_001245198                                                           15    9605
NP_001245184                                                           15    9605
NP_001245187                                                           15    9605
NP_001245186                                                           15    9605
NP_001245185                                                           15    9605
NP_001245188                                                           15    9605
NP_001245196                                                           15    9605
NP_001245189                                                           15    9605
NP_001245195                                                           15    9605
NP_001245180                                                           15    9605
NP_001245197                                                           15    9605
NP_001245179                                                           15    9605
NP_001245194                                                           15    9605
NP_001245183                                                           15    9605
NP_001245191                                                           15    9605
NP_001245199                                                           15    9605
NP_001245193                                                           15    9605
NP_001245178                                                           15    9605
NP_001245182                                                           15    9605
NP_001245181                                                           15    9605
NP_009056                                                              15    9605
NP_001245192                                                           15    9605
NP_872601                                                              15    9605
NP_872600                                                              15    9605
XP_006724939                                                           15    9605
XP_005262575                                                           15    9605
XP_006724938                                                           15    9605
XP_005272716                                                           15    9605
XP_005272715                                                           15    9605
XP_005272713                                                           15    9605
>NP_005091
          Length = 1782

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRSEASEKT 9
            D SEASEKT
Sbjct: 1633 DMSEASEKT 1641
>NP_653080
          Length = 1684

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRSEASEKT 9
            D SEASEKT
Sbjct: 1535 DMSEASEKT 1543
>XP_005267292
          Length = 1677

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRSEASEKT 9
            D SEASEKT
Sbjct: 1528 DMSEASEKT 1536
>XP_005267291
          Length = 1684

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRSEASEKT 9
            D SEASEKT
Sbjct: 1535 DMSEASEKT 1543
>XP_005267290
          Length = 1782

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRSEASEKT 9
            D SEASEKT
Sbjct: 1633 DMSEASEKT 1641
>NP_061961
          Length = 531

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DRSEASEKT 9
           DR EAS+K+
Sbjct: 424 DRDEASDKS 432
>NP_659417
          Length = 469

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DRSEASEK 8
           +RSE+SEK
Sbjct: 371 ERSESSEK 378
>NP_001273359
          Length = 606

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  DRSEASEKT 9
          +RSEASE++
Sbjct: 86 NRSEASERS 94
>NP_620147
          Length = 666

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  DRSEASEKT 9
          +RSEASE++
Sbjct: 86 NRSEASERS 94
>XP_006715416
          Length = 501

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DRSEASEK 8
           +RSE+SEK
Sbjct: 371 ERSESSEK 378
>XP_006715415
          Length = 501

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DRSEASEK 8
           +RSE+SEK
Sbjct: 371 ERSESSEK 378
>XP_005266895
          Length = 501

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DRSEASEK 8
           +RSE+SEK
Sbjct: 371 ERSESSEK 378
>NP_001074419
          Length = 1044

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRSEASEK 8
           DRSE S+K
Sbjct: 568 DRSELSDK 575
>NP_001074248
          Length = 1063

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRSEASEK 8
           DRSE S+K
Sbjct: 587 DRSELSDK 594
>NP_060193
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RSEASEKT 9
           R+EA EKT
Sbjct: 253 RAEAEEKT 260
>NP_203693
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRSEASEK 8
           DRSE S+K
Sbjct: 552 DRSELSDK 559
>XP_005256712
          Length = 1039

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRSEASEK 8
           DRSE S+K
Sbjct: 563 DRSELSDK 570
>NP_071921
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RSEASEKT 9
          RSE  EKT
Sbjct: 15 RSEGEEKT 22
>NP_596870
          Length = 5604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    RSEASEK 8
            RSEAS+K
Sbjct: 3733 RSEASDK 3739
>NP_001012398
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RSEASEKT 9
          RSE  EKT
Sbjct: 15 RSEGEEKT 22
>XP_005256155
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RSEASEKT 9
          RSE  EKT
Sbjct: 15 RSEGEEKT 22
>XP_005256154
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RSEASEKT 9
          RSE  EKT
Sbjct: 15 RSEGEEKT 22
>XP_005256153
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RSEASEKT 9
          RSE  EKT
Sbjct: 15 RSEGEEKT 22
>XP_005256152
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RSEASEKT 9
          RSE  EKT
Sbjct: 15 RSEGEEKT 22
>XP_005256151
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RSEASEKT 9
          RSE  EKT
Sbjct: 15 RSEGEEKT 22
>NP_001278350
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DRSEASEKT 9
          D+SEAS  T
Sbjct: 61 DKSEASADT 69
>NP_001278347
          Length = 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 312 DKSEASADT 320
>NP_001278346
          Length = 1356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 312 DKSEASADT 320
>NP_066963
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 312 DKSEASADT 320
>NP_001278345
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 312 DKSEASADT 320
>NP_001278344
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 312 DKSEASADT 320
>NP_055946
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DRSEASEK 8
           DR  ASEK
Sbjct: 653 DRDTASEK 660
>NP_001245198
          Length = 1293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245184
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245187
          Length = 1399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245186
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245185
          Length = 1335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245188
          Length = 1331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 293 DKSEASADT 301
>NP_001245196
          Length = 1342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245189
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245195
          Length = 1367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245180
          Length = 1363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245197
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245179
          Length = 1207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 293 DKSEASADT 301
>NP_001245194
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 226 DKSEASADT 234
>NP_001245183
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245191
          Length = 1320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245199
          Length = 1218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245193
          Length = 1376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 293 DKSEASADT 301
>NP_001245178
          Length = 1444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245182
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245181
          Length = 1392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_009056
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_001245192
          Length = 1290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_872601
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>NP_872600
          Length = 1240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>XP_006724939
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>XP_005262575
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>XP_006724938
          Length = 1234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 309 DKSEASADT 317
>XP_005272716
          Length = 1367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 312 DKSEASADT 320
>XP_005272715
          Length = 1374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 312 DKSEASADT 320
>XP_005272713
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DRSEASEKT 9
           D+SEAS  T
Sbjct: 312 DKSEASADT 320
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.276   0.0960    0.213 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 362,694
Number of extensions: 756
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.5 bits)
S2: 28 (15.4 bits)

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