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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              21     229
XP_005266703                                                           21     229
NP_003255                                                              17    2528
XP_005263250                                                           17    2528
XP_005263252                                                           17    2528
XP_005263253                                                           17    2528
XP_005263254                                                           17    2528
XP_005263251                                                           17    2528
NP_001025051                                                           17    4312
NP_001018049                                                           17    4312
XP_005252608                                                           17    4312
XP_006717553                                                           17    4312
NP_002308                                                              16    5631
NP_001171573                                                           16    5631
NP_001193665                                                           16    5631
NP_061327                                                              16    5631
NP_057227                                                              16    5631
XP_006723657                                                           16    5631
XP_006723656                                                           16    5631
XP_006723655                                                           16    5631
XP_006723654                                                           16    5631
NP_002635                                                              16    7355
XP_005262478                                                           16    7355
XP_005273220                                                           16    7355
NP_115495                                                              15    9605
NP_000866                                                              15    9605
NP_066957                                                              15    9605
NP_443190                                                              15    9605
NP_001182568                                                           15    9605
XP_006724959                                                           15    9605
XP_005254954                                                           15    9605
XP_005254953                                                           15    9605
XP_006720550                                                           15    9605
XP_006720549                                                           15    9605
XP_006718334                                                           15    9605
XP_005251206                                                           15    9605
XP_006710481                                                           15    9605

>NP_443179
          Length = 2170

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRADLRSYE 9
            DRAD RSYE
Sbjct: 1115 DRADFRSYE 1123



>XP_005266703
          Length = 1501

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DRADLRSYE 9
           DRAD RSYE
Sbjct: 446 DRADFRSYE 454



>NP_003255
          Length = 784

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DRADLRSYE 9
           D +DL+SYE
Sbjct: 182 DASDLQSYE 190



>XP_005263250
          Length = 784

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DRADLRSYE 9
           D +DL+SYE
Sbjct: 182 DASDLQSYE 190



>XP_005263252
          Length = 784

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DRADLRSYE 9
           D +DL+SYE
Sbjct: 182 DASDLQSYE 190



>XP_005263253
          Length = 784

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DRADLRSYE 9
           D +DL+SYE
Sbjct: 182 DASDLQSYE 190



>XP_005263254
          Length = 784

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DRADLRSYE 9
           D +DL+SYE
Sbjct: 182 DASDLQSYE 190



>XP_005263251
          Length = 784

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DRADLRSYE 9
           D +DL+SYE
Sbjct: 182 DASDLQSYE 190



>NP_001025051
          Length = 894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRADLRSY 8
           D ADLRS+
Sbjct: 291 DHADLRSH 298



>NP_001018049
          Length = 894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRADLRSY 8
           D ADLRS+
Sbjct: 291 DHADLRSH 298



>XP_005252608
          Length = 642

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DRADLRSY 8
          D ADLRS+
Sbjct: 39 DHADLRSH 46



>XP_006717553
          Length = 725

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRADLRSY 8
           D ADLRS+
Sbjct: 122 DHADLRSH 129



>NP_002308
          Length = 417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RADLRSYE 9
           RAD+R Y+
Sbjct: 251 RADVRDYD 258



>NP_001171573
          Length = 187

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RADLRSYE 9
          RAD+R Y+
Sbjct: 21 RADVRDYD 28



>NP_001193665
          Length = 372

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DRADLRSYE 9
           D  +LRSY+
Sbjct: 196 DNGELRSYQ 204



>NP_061327
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DRADLRSYE 9
           D  +LRSY+
Sbjct: 163 DNGELRSYQ 171



>NP_057227
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DRADLRSYE 9
           D  +LRSY+
Sbjct: 194 DNGELRSYQ 202



>XP_006723657
          Length = 259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DRADLRSYE 9
          D  +LRSY+
Sbjct: 83 DNGELRSYQ 91



>XP_006723656
          Length = 261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DRADLRSYE 9
          D  +LRSY+
Sbjct: 85 DNGELRSYQ 93



>XP_006723655
          Length = 261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DRADLRSYE 9
          D  +LRSY+
Sbjct: 85 DNGELRSYQ 93



>XP_006723654
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DRADLRSYE 9
           D  +LRSY+
Sbjct: 109 DNGELRSYQ 117



>NP_002635
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DRADLRSY 8
           DR  +RSY
Sbjct: 670 DRVSIRSY 677



>XP_005262478
          Length = 835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DRADLRSYE 9
          DR + +SYE
Sbjct: 4  DRVERKSYE 12



>XP_005273220
          Length = 773

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DRADLRSY 8
           DR  +RSY
Sbjct: 670 DRVSIRSY 677



>NP_115495
          Length = 6306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    DLRSYE 9
            D+RSYE
Sbjct: 1482 DVRSYE 1487



>NP_000866
          Length = 1367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RADLRSY 8
            R DL+SY
Sbjct: 1084 RGDLKSY 1090



>NP_066957
          Length = 153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  RADLRSY 8
          R DLR+Y
Sbjct: 50 RVDLRNY 56



>NP_443190
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RADLRSYE 9
           R D RSY+
Sbjct: 164 RRDFRSYD 171



>NP_001182568
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RADLRSYE 9
           R D RSY+
Sbjct: 164 RRDFRSYD 171



>XP_006724959
          Length = 153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  RADLRSY 8
          R DLR+Y
Sbjct: 50 RVDLRNY 56



>XP_005254954
          Length = 1246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   RADLRSY 8
           R DL+SY
Sbjct: 963 RGDLKSY 969



>XP_005254953
          Length = 1366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RADLRSY 8
            R DL+SY
Sbjct: 1083 RGDLKSY 1089



>XP_006720550
          Length = 1373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RADLRSY 8
            R DL+SY
Sbjct: 1090 RGDLKSY 1096



>XP_006720549
          Length = 1374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RADLRSY 8
            R DL+SY
Sbjct: 1091 RGDLKSY 1097



>XP_006718334
          Length = 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  RADLRSY 8
          R DLR+Y
Sbjct: 50 RVDLRNY 56



>XP_005251206
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RADLRSYE 9
           R D RSY+
Sbjct: 164 RRDFRSYD 171



>XP_006710481
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RADLRS 7
           RADLRS
Sbjct: 463 RADLRS 468



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.133    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 482,663
Number of extensions: 925
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)