Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              18    1135
XP_005250103                                                           18    1135
XP_005250102                                                           18    1135
NP_203746                                                              17    3301
NP_203751                                                              17    3301
NP_001163935                                                           17    3301
NP_002586                                                              17    3301
XP_006719507                                                           17    3301
XP_006718797                                                           17    3301
XP_005274435                                                           17    3301
XP_006718795                                                           17    3301
XP_005274433                                                           17    3301
XP_006714457                                                           17    3301
XP_006714456                                                           17    3301
XP_005263376                                                           17    3301
NP_077288                                                              16    5631
NP_001138570                                                           16    5631
NP_001234937                                                           16    5631
NP_001138569                                                           16    5631
NP_005405                                                              16    5631
NP_056083                                                              16    5631
NP_212133                                                              16    5631
NP_940938                                                              16    5631
NP_001138888                                                           16    5631
XP_005259958                                                           16    5631
XP_005259957                                                           16    5631
XP_005259959                                                           16    5631
XP_005259956                                                           16    5631
XP_005259955                                                           16    5631
XP_006719656                                                           16    5631
XP_006713798                                                           16    5631
XP_005247778                                                           16    5631
XP_005247302                                                           16    5631
NP_003142                                                              16    7355
NP_001230764                                                           16    7355
NP_001071107                                                           16    7355
XP_006718928                                                           16    7355
XP_006712782                                                           16    7355
XP_005246874                                                           16    7355
NP_036492                                                              16    7355
NP_001116212                                                           15    9605
NP_005912                                                              15    9605
NP_001116214                                                           15    9605
NP_000116                                                              15    9605
NP_001116213                                                           15    9605
NP_001278159                                                           15    9605
NP_001278170                                                           15    9605
NP_002587                                                              15    9605
NP_055523                                                              15    9605
NP_001258966                                                           15    9605
NP_001128248                                                           15    9605
NP_001128247                                                           15    9605
NP_663782                                                              15    9605
NP_071940                                                              15    9605
NP_001118                                                              15    9605
NP_659428                                                              15    9605
NP_065810                                                              15    9605
NP_997667                                                              15    9605
XP_005261214                                                           15    9605
XP_006720684                                                           15    9605
XP_005268066                                                           15    9605
XP_006719769                                                           15    9605
XP_006718728                                                           15    9605
XP_005274241                                                           15    9605
XP_005274240                                                           15    9605
XP_005274239                                                           15    9605
XP_006715438                                                           15    9605
XP_006715437                                                           15    9605
XP_005248577                                                           15    9605
XP_005248576                                                           15    9605
XP_006711428                                                           15    9605
NP_997668                                                              15    9605
NP_001159491                                                           15    9605
NP_073733                                                              15    9605
>NP_004324
          Length = 766

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           DQL LLFVS
Sbjct: 284 DQLDLLFVS 292
>XP_005250103
          Length = 758

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           DQL LLFVS
Sbjct: 284 DQLDLLFVS 292
>XP_005250102
          Length = 767

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           DQL LLFVS
Sbjct: 284 DQLDLLFVS 292
>NP_203746
          Length = 619

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DQLHLLFVS 9
           DQLHLL  S
Sbjct: 513 DQLHLLSCS 521
>NP_203751
          Length = 1143

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QLHLLFV 8
           +LHLLFV
Sbjct: 376 ELHLLFV 382
>NP_001163935
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DQLHLLF 7
           D+LHL+F
Sbjct: 396 DELHLIF 402
>NP_002586
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DQLHLLF 7
           D+LHL+F
Sbjct: 396 DELHLIF 402
>XP_006719507
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DQLHLLF 7
           D+LHL+F
Sbjct: 396 DELHLIF 402
>XP_006718797
          Length = 334

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DQLHLLFVS 9
           DQLHLL  S
Sbjct: 228 DQLHLLSCS 236
>XP_005274435
          Length = 513

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DQLHLLFVS 9
           DQLHLL  S
Sbjct: 407 DQLHLLSCS 415
>XP_006718795
          Length = 598

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DQLHLLFVS 9
           DQLHLL  S
Sbjct: 492 DQLHLLSCS 500
>XP_005274433
          Length = 604

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DQLHLLFVS 9
           DQLHLL  S
Sbjct: 513 DQLHLLSCS 521
>XP_006714457
          Length = 809

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QLHLLFV 8
          +LHLLFV
Sbjct: 42 ELHLLFV 48
>XP_006714456
          Length = 1143

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QLHLLFV 8
           +LHLLFV
Sbjct: 376 ELHLLFV 382
>XP_005263376
          Length = 1143

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QLHLLFV 8
           +LHLLFV
Sbjct: 376 ELHLLFV 382
>NP_077288
          Length = 1256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DQLHLLFVS 9
          DQ H+LF S
Sbjct: 47 DQYHVLFDS 55
>NP_001138570
          Length = 664

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQLHLLFV 8
           DQLH+L V
Sbjct: 180 DQLHILKV 187
>NP_001234937
          Length = 684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQLHLLFV 8
           DQLH+L V
Sbjct: 200 DQLHILKV 207
>NP_001138569
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQLHLLFV 8
           DQLH+L V
Sbjct: 200 DQLHILKV 207
>NP_005405
          Length = 684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQLHLLFV 8
           DQLH+L V
Sbjct: 200 DQLHILKV 207
>NP_056083
          Length = 2243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DQLHLLFVS 9
            DQ H LF+S
Sbjct: 2191 DQKHDLFIS 2199
>NP_212133
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QLHLLFVS 9
          QL+LLF+S
Sbjct: 88 QLYLLFLS 95
>NP_940938
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QLHLLFVS 9
          QL+LLF+S
Sbjct: 88 QLYLLFLS 95
>NP_001138888
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QLHLLFVS 9
          QL+LLF+S
Sbjct: 88 QLYLLFLS 95
>XP_005259958
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QLHLLFVS 9
          QL+LLF+S
Sbjct: 88 QLYLLFLS 95
>XP_005259957
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QLHLLFVS 9
          QL+LLF+S
Sbjct: 88 QLYLLFLS 95
>XP_005259959
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QLHLLFVS 9
          QL+LLF+S
Sbjct: 88 QLYLLFLS 95
>XP_005259956
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QLHLLFVS 9
          QL+LLF+S
Sbjct: 88 QLYLLFLS 95
>XP_005259955
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QLHLLFVS 9
          QL+LLF+S
Sbjct: 88 QLYLLFLS 95
>XP_006719656
          Length = 1179

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DQLHLLFVS 9
          DQ H+LF S
Sbjct: 47 DQYHVLFDS 55
>XP_006713798
          Length = 684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQLHLLFV 8
           DQLH+L V
Sbjct: 200 DQLHILKV 207
>XP_005247778
          Length = 684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQLHLLFV 8
           DQLH+L V
Sbjct: 200 DQLHILKV 207
>XP_005247302
          Length = 2248

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DQLHLLFVS 9
            DQ H LF+S
Sbjct: 2196 DQKHDLFIS 2204
>NP_003142
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQLH+L
Sbjct: 513 DQLHML 518
>NP_001230764
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQLH+L
Sbjct: 513 DQLHML 518
>NP_001071107
          Length = 544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQLH+L
Sbjct: 115 DQLHIL 120
>XP_006718928
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQLH+L
Sbjct: 115 DQLHIL 120
>XP_006712782
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQLH+L
Sbjct: 513 DQLHML 518
>XP_005246874
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQLH+L
Sbjct: 522 DQLHML 527
>NP_036492
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  QLHLLFV 8
          Q HLLFV
Sbjct: 23 QQHLLFV 29
>NP_001116212
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQ+HLL
Sbjct: 374 DQVHLL 379
>NP_005912
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LHLLFV 8
           +HLLFV
Sbjct: 356 IHLLFV 361
>NP_001116214
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQ+HLL
Sbjct: 374 DQVHLL 379
>NP_000116
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQ+HLL
Sbjct: 374 DQVHLL 379
>NP_001116213
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQ+HLL
Sbjct: 374 DQVHLL 379
>NP_001278159
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQ+HLL
Sbjct: 376 DQVHLL 381
>NP_001278170
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQ+HLL
Sbjct: 373 DQVHLL 378
>NP_002587
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DQLHLLF 7
           ++LHL+F
Sbjct: 348 EELHLIF 354
>NP_055523
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  QLHLLF 7
          QLHL+F
Sbjct: 78 QLHLVF 83
>NP_001258966
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  QLHLLFV 8
          QLH LF+
Sbjct: 59 QLHFLFL 65
>NP_001128248
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           ++ HLLF+S
Sbjct: 133 EKQHLLFMS 141
>NP_001128247
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           ++ HLLF+S
Sbjct: 133 EKQHLLFMS 141
>NP_663782
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LHLLFV 8
           LH+LFV
Sbjct: 824 LHILFV 829
>NP_071940
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LHLLFV 8
          LH+LFV
Sbjct: 11 LHILFV 16
>NP_001118
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LHLLFV 8
           LH+LFV
Sbjct: 831 LHILFV 836
>NP_659428
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QLHLLFV 8
           QLH LF+
Sbjct: 127 QLHFLFL 133
>NP_065810
          Length = 4700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLHLLFVS 9
           QLH +F+S
Sbjct: 843 QLHSIFLS 850
>NP_997667
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DQLHLLF 7
           ++LHL+F
Sbjct: 348 EELHLIF 354
>XP_005261214
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  QLHLLFV 8
          QLH LF+
Sbjct: 59 QLHFLFL 65
>XP_006720684
          Length = 4713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLHLLFVS 9
           QLH +F+S
Sbjct: 856 QLHSIFLS 863
>XP_005268066
          Length = 1172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LHLLFV 8
           LH+LFV
Sbjct: 245 LHILFV 250
>XP_006719769
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  QLHLLF 7
          QLHL+F
Sbjct: 78 QLHLVF 83
>XP_006718728
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           ++ HLLF+S
Sbjct: 133 EKQHLLFMS 141
>XP_005274241
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           ++ HLLF+S
Sbjct: 133 EKQHLLFMS 141
>XP_005274240
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           ++ HLLF+S
Sbjct: 133 EKQHLLFMS 141
>XP_005274239
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           ++ HLLF+S
Sbjct: 133 EKQHLLFMS 141
>XP_006715438
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQ+HLL
Sbjct: 201 DQVHLL 206
>XP_006715437
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQLHLL 6
           DQ+HLL
Sbjct: 374 DQVHLL 379
>XP_005248577
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LHLLFV 8
           +HLLFV
Sbjct: 193 IHLLFV 198
>XP_005248576
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LHLLFV 8
           +HLLFV
Sbjct: 219 IHLLFV 224
>XP_006711428
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DQLHLLF 7
           ++LHL+F
Sbjct: 378 EELHLIF 384
>NP_997668
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DQLHLLF 7
           ++LHL+F
Sbjct: 378 EELHLIF 384
>NP_001159491
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LHLLFV 8
           LH+LFV
Sbjct: 804 LHILFV 809
>NP_073733
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DQLHLLFVS 9
           ++ HLLF+S
Sbjct: 133 EKQHLLFMS 141
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.149    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 618,210
Number of extensions: 1218
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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