Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              21     229
XP_005251512                                                           21     229
NP_001275582                                                           17    3301
NP_004850                                                              17    3301
XP_005257069                                                           17    3301
NP_003945                                                              16    5631
NP_874358                                                              16    5631
NP_660207                                                              16    7355
NP_005161                                                              16    7355
NP_055462                                                              16    7355
NP_001171928                                                           16    7355
NP_001171927                                                           16    7355
XP_006725283                                                           16    7355
XP_006725281                                                           16    7355
XP_006725280                                                           16    7355
XP_006725279                                                           16    7355
XP_006725278                                                           16    7355
XP_006721049                                                           16    7355
XP_005255764                                                           16    7355
XP_005255763                                                           16    7355
XP_005255762                                                           16    7355
XP_005255761                                                           16    7355
XP_005269605                                                           16    7355
XP_005269604                                                           16    7355
XP_005269603                                                           16    7355
XP_005269602                                                           16    7355
XP_005269601                                                           16    7355
XP_006717700                                                           16    7355
XP_006717699                                                           16    7355
XP_005269600                                                           16    7355
NP_077288                                                              15    9605
XP_006719656                                                           15    9605
NP_062545                                                              15    9605



>NP_004963
          Length = 1132

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DQIRNNMAG 9
            DQIR+NMAG
Sbjct: 1124 DQIRDNMAG 1132





>XP_005251512
          Length = 1132

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DQIRNNMAG 9
            DQIR+NMAG
Sbjct: 1124 DQIRDNMAG 1132





>NP_001275582
          Length = 1679

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IRNNMAG 9
           +RNN+AG
Sbjct: 357 VRNNLAG 363





>NP_004850
          Length = 1675

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IRNNMAG 9
           +RNN+AG
Sbjct: 353 VRNNLAG 359





>XP_005257069
          Length = 1682

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IRNNMAG 9
           +RNN+AG
Sbjct: 353 VRNNLAG 359





>NP_003945
          Length = 947

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQIRNNMA 8
           DQI NN+A
Sbjct: 115 DQIPNNVA 122





>NP_874358
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QIRNNMAG 9
          +I+NNM G
Sbjct: 54 KIKNNMVG 61





>NP_660207
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>NP_005161
          Length = 193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D +RN +AG
Sbjct: 110 DAVRNALAG 118





>NP_055462
          Length = 1742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>NP_001171928
          Length = 1739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>NP_001171927
          Length = 1742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_006725283
          Length = 1600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_006725281
          Length = 1733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_006725280
          Length = 1741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_006725279
          Length = 1743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_006725278
          Length = 1743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_006721049
          Length = 1600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_005255764
          Length = 1733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_005255763
          Length = 1741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_005255762
          Length = 1743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_005255761
          Length = 1743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RNNMAG 9
           RNN+AG
Sbjct: 166 RNNLAG 171





>XP_005269605
          Length = 187

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>XP_005269604
          Length = 191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>XP_005269603
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>XP_005269602
          Length = 198

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>XP_005269601
          Length = 203

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>XP_006717700
          Length = 205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>XP_006717699
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>XP_005269600
          Length = 224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DQIRNNMAG 9
           D++RN + G
Sbjct: 97  DEVRNELLG 105





>NP_077288
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DQIRNNMAG 9
          D  R+N+AG
Sbjct: 54 DSYRDNIAG 62





>XP_006719656
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DQIRNNMAG 9
          D  R+N+AG
Sbjct: 54 DSYRDNIAG 62





>NP_062545
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QIRNNMAG 9
           Q+RN +AG
Sbjct: 207 QMRNTVAG 214





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.130    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 453,798
Number of extensions: 696
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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