Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              21     175
NP_057533                                                              16    5631
NP_061152                                                              16    5631
NP_891847                                                              16    5631
NP_874358                                                              16    5631
NP_872296                                                              16    5631
NP_001276101                                                           16    5631
NP_001276100                                                           16    5631
NP_001276099                                                           16    5631
NP_001276098                                                           16    5631
NP_001276097                                                           16    5631
NP_001276096                                                           16    5631
NP_001276095                                                           16    5631
XP_006726899                                                           16    5631
XP_006724472                                                           16    5631
XP_005261681                                                           16    5631
XP_006724322                                                           16    5631
XP_006723434                                                           16    5631
XP_006723433                                                           16    5631
XP_005259289                                                           16    5631
XP_005254225                                                           16    5631
XP_006716112                                                           16    5631
XP_005250550                                                           16    5631
XP_006710183                                                           16    5631
NP_689666                                                              16    5631
NP_001276102                                                           16    5631
NP_997239                                                              16    7355
NP_036442                                                              16    7355
NP_116242                                                              16    7355
XP_006711974                                                           16    7355
XP_005245134                                                           16    7355
XP_005244800                                                           16    7355
NP_001139669                                                           16    7355
NP_620077                                                              16    7355
NP_689777                                                              15    9605
NP_060360                                                              15    9605
NP_056058                                                              15    9605
NP_858047                                                              15    9605
NP_001122312                                                           15    9605
NP_001122311                                                           15    9605
NP_000711                                                              15    9605
NP_001269901                                                           15    9605
NP_001139447                                                           15    9605
NP_003975                                                              15    9605
NP_055983                                                              15    9605
NP_001074011                                                           15    9605
NP_005678                                                              15    9605
XP_005258735                                                           15    9605
XP_005258734                                                           15    9605
XP_005258733                                                           15    9605
XP_006723176                                                           15    9605
XP_006722228                                                           15    9605
XP_006716574                                                           15    9605
XP_006716573                                                           15    9605
XP_005250858                                                           15    9605
XP_005250857                                                           15    9605
XP_005265505                                                           15    9605
XP_006713388                                                           15    9605
XP_006712610                                                           15    9605
XP_006712609                                                           15    9605
XP_006712233                                                           15    9605
XP_006712232                                                           15    9605
XP_006712231                                                           15    9605
NP_001017415                                                           15    9605
NP_003359                                                              15    9605
NP_001017416                                                           15    9605
>NP_115803
          Length = 1156

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DQANQKMPS 9
           DQANQ+MPS
Sbjct: 565 DQANQQMPS 573
>NP_057533
          Length = 229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ANQKMPS 9
          +NQKMP+
Sbjct: 63 SNQKMPT 69
>NP_061152
          Length = 1858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DQANQKMPS 9
            +Q +QK+PS
Sbjct: 1426 EQLSQKLPS 1434
>NP_891847
          Length = 1858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DQANQKMPS 9
            +Q +QK+PS
Sbjct: 1426 EQLSQKLPS 1434
>NP_874358
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D+ANQ +P
Sbjct: 587 DRANQSVP 594
>NP_872296
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 237 DGSNQKLP 244
>NP_001276101
          Length = 702

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 140 DGSNQKLP 147
>NP_001276100
          Length = 720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 158 DGSNQKLP 165
>NP_001276099
          Length = 720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 158 DGSNQKLP 165
>NP_001276098
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 186 DGSNQKLP 193
>NP_001276097
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 186 DGSNQKLP 193
>NP_001276096
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 186 DGSNQKLP 193
>NP_001276095
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 237 DGSNQKLP 244
>XP_006726899
          Length = 197

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ANQKMPS 9
           +NQKMP+
Sbjct: 109 SNQKMPT 115
>XP_006724472
          Length = 200

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ANQKMPS 9
           +NQKMP+
Sbjct: 112 SNQKMPT 118
>XP_005261681
          Length = 145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ANQKMPS 9
          +NQKMP+
Sbjct: 63 SNQKMPT 69
>XP_006724322
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ANQKMPS 9
          +NQKMP+
Sbjct: 63 SNQKMPT 69
>XP_006723434
          Length = 771

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 209 DGSNQKLP 216
>XP_006723433
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 237 DGSNQKLP 244
>XP_005259289
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 237 DGSNQKLP 244
>XP_005254225
          Length = 288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DQANQKM 7
          D+ANQK+
Sbjct: 28 DEANQKL 34
>XP_006716112
          Length = 1816

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DQANQKMPS 9
            +Q +QK+PS
Sbjct: 1384 EQLSQKLPS 1392
>XP_005250550
          Length = 1858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DQANQKMPS 9
            +Q +QK+PS
Sbjct: 1426 EQLSQKLPS 1434
>XP_006710183
          Length = 200

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ANQKMPS 9
           +NQKMP+
Sbjct: 112 SNQKMPT 118
>NP_689666
          Length = 288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DQANQKM 7
          D+ANQK+
Sbjct: 28 DEANQKL 34
>NP_001276102
          Length = 771

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQANQKMP 8
           D +NQK+P
Sbjct: 209 DGSNQKLP 216
>NP_997239
          Length = 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DQANQKMP 8
           D +NQ MP
Sbjct: 187 DDSNQPMP 194
>NP_036442
          Length = 1232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DQANQKM 7
           +QAN+KM
Sbjct: 424 EQANEKM 430
>NP_116242
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DQANQKM 7
           D+ANQK+
Sbjct: 570 DRANQKL 576
>XP_006711974
          Length = 366

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QANQKMPS 9
           +ANQKM S
Sbjct: 355 EANQKMNS 362
>XP_005245134
          Length = 235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  QANQKMP 8
          Q NQK+P
Sbjct: 92 QGNQKIP 98
>XP_005244800
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DQANQKMP 8
           D +NQ MP
Sbjct: 198 DDSNQPMP 205
>NP_001139669
          Length = 7081

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QANQKMP 8
            +ANQ+MP
Sbjct: 4872 KANQQMP 4878
>NP_620077
          Length = 201

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  QANQKMP 8
          Q NQK+P
Sbjct: 58 QGNQKIP 64
>NP_689777
          Length = 3997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DQANQKMPS 9
           +  N KMPS
Sbjct: 243 ENLNSKMPS 251
>NP_060360
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DQANQKMPS 9
           +  N KMPS
Sbjct: 243 ENLNSKMPS 251
>NP_056058
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DQANQKMPS 9
           +  N KMPS
Sbjct: 243 ENLNSKMPS 251
>NP_858047
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DQANQKMPS 9
           +  N KMPS
Sbjct: 243 ENLNSKMPS 251
>NP_001122312
          Length = 2161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DQANQKMPS 9
            DQ N  +PS
Sbjct: 2010 DQVNGSLPS 2018
>NP_001122311
          Length = 2137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DQANQKMPS 9
            DQ N  +PS
Sbjct: 1986 DQVNGSLPS 1994
>NP_000711
          Length = 2181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DQANQKMPS 9
            DQ N  +PS
Sbjct: 2030 DQVNGSLPS 2038
>NP_001269901
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DQANQKM 7
          D+A+QKM
Sbjct: 30 DEASQKM 36
>NP_001139447
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   NQKMP 8
           NQKMP
Sbjct: 463 NQKMP 467
>NP_003975
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   NQKMP 8
           NQKMP
Sbjct: 414 NQKMP 418
>NP_055983
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DQANQKMPS 9
           D  N+K+PS
Sbjct: 574 DMYNKKIPS 582
>NP_001074011
          Length = 1133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DQANQKMPS 9
            D+A Q +PS
Sbjct: 1041 DRARQDLPS 1049
>NP_005678
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ANQKMP 8
           AN+KMP
Sbjct: 464 ANRKMP 469
>XP_005258735
          Length = 1254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DQANQKMPS 9
           D  N+K+PS
Sbjct: 525 DMYNKKIPS 533
>XP_005258734
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DQANQKMPS 9
           D  N+K+PS
Sbjct: 533 DMYNKKIPS 541
>XP_005258733
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DQANQKMPS 9
           D  N+K+PS
Sbjct: 538 DMYNKKIPS 546
>XP_006723176
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DQANQKMPS 9
           D  N+K+PS
Sbjct: 574 DMYNKKIPS 582
>XP_006722228
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   NQKMP 8
           NQKMP
Sbjct: 371 NQKMP 375
>XP_006716574
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DQANQKMPS 9
           +  N KMPS
Sbjct: 243 ENLNSKMPS 251
>XP_006716573
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DQANQKMPS 9
           +  N KMPS
Sbjct: 243 ENLNSKMPS 251
>XP_005250858
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DQANQKMPS 9
           +  N KMPS
Sbjct: 243 ENLNSKMPS 251
>XP_005250857
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DQANQKMPS 9
           +  N KMPS
Sbjct: 243 ENLNSKMPS 251
>XP_005265505
          Length = 2146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DQANQKMPS 9
            DQ N  +PS
Sbjct: 1995 DQVNGSLPS 2003
>XP_006713388
          Length = 2194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DQANQKMPS 9
            DQ N  +PS
Sbjct: 2043 DQVNGSLPS 2051
>XP_006712610
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DQANQKM 7
          D+A+QKM
Sbjct: 57 DEASQKM 63
>XP_006712609
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DQANQKM 7
          D+A+QKM
Sbjct: 62 DEASQKM 68
>XP_006712233
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ANQKMP 8
           AN+KMP
Sbjct: 365 ANRKMP 370
>XP_006712232
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ANQKMP 8
           AN+KMP
Sbjct: 365 ANRKMP 370
>XP_006712231
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ANQKMP 8
           AN+KMP
Sbjct: 365 ANRKMP 370
>NP_001017415
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQANQK 6
           D+ANQK
Sbjct: 125 DEANQK 130
>NP_003359
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQANQK 6
           D+ANQK
Sbjct: 125 DEANQK 130
>NP_001017416
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DQANQK 6
           D+ANQK
Sbjct: 125 DEANQK 130
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.108    0.285 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 546,450
Number of extensions: 1000
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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