Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     869
NP_001185763                                                           19     869
NP_055459                                                              19     869
XP_006726410                                                           19     869
XP_006711719                                                           19     869
XP_006711718                                                           19     869
XP_006711717                                                           19     869
XP_006711716                                                           19     869
XP_006711715                                                           19     869
XP_006711714                                                           19     869
XP_006711713                                                           19     869
XP_006711712                                                           19     869
XP_006711711                                                           19     869
XP_006711710                                                           19     869
XP_006711709                                                           19     869
XP_005277503                                                           19     869
XP_005273038                                                           19     869
XP_006711708                                                           19     869
XP_005277500                                                           19     869
XP_006711707                                                           19     869
XP_005277499                                                           19     869
XP_006711706                                                           19     869
XP_006711705                                                           19     869
XP_006711164                                                           19     869
XP_006710143                                                           19     869
XP_006710142                                                           19     869
XP_006710141                                                           19     869
NP_001230586                                                           17    2528
NP_476506                                                              16    5631
NP_476505                                                              16    5631
NP_004360                                                              16    5631
NP_476508                                                              16    5631
NP_476507                                                              16    5631
NP_078934                                                              16    5631
XP_005246123                                                           16    5631
XP_005246122                                                           16    5631
XP_006712316                                                           16    5631
NP_056073                                                              16    7355
NP_004555                                                              16    7355
XP_005276585                                                           16    7355
XP_005255567                                                           16    7355
XP_005255566                                                           16    7355
XP_370934                                                              16    7355
XP_006717082                                                           16    7355
XP_006717081                                                           16    7355
XP_001716413                                                           16    7355
NP_001269852                                                           15    9605
NP_060260                                                              15    9605
NP_001263190                                                           15    9605
NP_652759                                                              15    9605
NP_570613                                                              15    9605
NP_683866                                                              15    9605
NP_055495                                                              15    9605
NP_003781                                                              15    9605
NP_683868                                                              15    9605
NP_683871                                                              15    9605
XP_006722261                                                           15    9605
XP_005258130                                                           15    9605
XP_006717286                                                           15    9605
XP_006717284                                                           15    9605
XP_006717283                                                           15    9605
XP_006717282                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1514 DQAGLEPLA 1522
>NP_001185763
          Length = 2362

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1558 DQAGLEPLA 1566
>NP_055459
          Length = 2346

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1558 DQAGLEPLA 1566
>XP_006726410
          Length = 2087

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1361 DQAGLEPLA 1369
>XP_006711719
          Length = 2302

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1514 DQAGLEPLA 1522
>XP_006711718
          Length = 1436

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQAGLE LA
Sbjct: 565 DQAGLEPLA 573
>XP_006711717
          Length = 2385

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1514 DQAGLEPLA 1522
>XP_006711716
          Length = 2411

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1623 DQAGLEPLA 1631
>XP_006711715
          Length = 2428

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1557 DQAGLEPLA 1565
>XP_006711714
          Length = 2429

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1558 DQAGLEPLA 1566
>XP_006711713
          Length = 2432

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1561 DQAGLEPLA 1569
>XP_006711712
          Length = 2473

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1721 DQAGLEPLA 1729
>XP_006711711
          Length = 2482

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1611 DQAGLEPLA 1619
>XP_006711710
          Length = 2494

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1623 DQAGLEPLA 1631
>XP_006711709
          Length = 2495

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1624 DQAGLEPLA 1632
>XP_005277503
          Length = 2498

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1721 DQAGLEPLA 1729
>XP_005273038
          Length = 2509

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1721 DQAGLEPLA 1729
>XP_006711708
          Length = 2512

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1721 DQAGLEPLA 1729
>XP_005277500
          Length = 2525

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1721 DQAGLEPLA 1729
>XP_006711707
          Length = 2553

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1721 DQAGLEPLA 1729
>XP_005277499
          Length = 2561

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1721 DQAGLEPLA 1729
>XP_006711706
          Length = 2591

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1720 DQAGLEPLA 1728
>XP_006711705
          Length = 2592

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1721 DQAGLEPLA 1729
>XP_006711164
          Length = 2087

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DQAGLEQLA 9
            DQAGLE LA
Sbjct: 1361 DQAGLEPLA 1369
>XP_006710143
          Length = 562

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQAGLE LA
Sbjct: 400 DQAGLEPLA 408
>XP_006710142
          Length = 671

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQAGLE LA
Sbjct: 509 DQAGLEPLA 517
>XP_006710141
          Length = 672

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQAGLE LA
Sbjct: 510 DQAGLEPLA 518
>NP_001230586
          Length = 170

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           D+AGLE LA
Sbjct: 124 DEAGLELLA 132
>NP_476506
          Length = 1237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQA LE++A
Sbjct: 382 DQAELEEIA 390
>NP_476505
          Length = 1036

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQA LE++A
Sbjct: 181 DQAELEEIA 189
>NP_004360
          Length = 3177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQA LE++A
Sbjct: 588 DQAELEEIA 596
>NP_476508
          Length = 2971

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQA LE++A
Sbjct: 382 DQAELEEIA 390
>NP_476507
          Length = 2570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQA LE++A
Sbjct: 181 DQAELEEIA 189
>NP_078934
          Length = 1081

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1 DQAGLEQL 8
         + AGLEQL
Sbjct: 2 ESAGLEQL 9
>XP_005246123
          Length = 2770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQA LE++A
Sbjct: 181 DQAELEEIA 189
>XP_005246122
          Length = 2977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQA LE++A
Sbjct: 588 DQAELEEIA 596
>XP_006712316
          Length = 3010

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQAGLEQLA 9
           DQA LE++A
Sbjct: 588 DQAELEEIA 596
>NP_056073
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DQAGLEQLA 9
           DQA  EQL+
Sbjct: 787 DQAAAEQLS 795
>NP_004555
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DQAGLEQL 8
           DQ  LEQL
Sbjct: 497 DQGALEQL 504
>XP_005276585
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QAGLEQL 8
           Q GLEQL
Sbjct: 320 QVGLEQL 326
>XP_005255567
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AGLEQLA 9
           AGLEQL+
Sbjct: 152 AGLEQLS 158
>XP_005255566
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AGLEQLA 9
           AGLEQL+
Sbjct: 153 AGLEQLS 159
>XP_370934
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QAGLEQL 8
           Q GLEQL
Sbjct: 320 QVGLEQL 326
>XP_006717082
          Length = 1151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DQAGLEQLA 9
           DQA  EQL+
Sbjct: 719 DQAAAEQLS 727
>XP_006717081
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DQAGLEQLA 9
           DQA  EQL+
Sbjct: 777 DQAAAEQLS 785
>XP_001716413
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QAGLEQL 8
           Q GLEQL
Sbjct: 320 QVGLEQL 326
>NP_001269852
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQAGLEQL 8
           ++AGL+QL
Sbjct: 221 ERAGLQQL 228
>NP_060260
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQAGLEQL 8
           ++AGL+QL
Sbjct: 219 ERAGLQQL 226
>NP_001263190
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  DQAGLEQL 8
          ++AGL+QL
Sbjct: 50 ERAGLQQL 57
>NP_652759
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQAGLEQL 8
           ++AGL+QL
Sbjct: 331 ERAGLQQL 338
>NP_570613
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  DQAGLEQL 8
          ++AGL+QL
Sbjct: 50 ERAGLQQL 57
>NP_683866
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQAGLEQL 8
           D+AG+E L
Sbjct: 246 DEAGMEAL 253
>NP_055495
          Length = 2235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DQAGLEQLA 9
            +QA L QLA
Sbjct: 1145 EQANLHQLA 1153
>NP_003781
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQAGLEQL 8
           D+AG+E L
Sbjct: 237 DEAGMEAL 244
>NP_683868
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DQAGLEQL 8
           D+AG+E L
Sbjct: 192 DEAGMEAL 199
>NP_683871
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DQAGLEQL 8
          D+AG+E L
Sbjct: 54 DEAGMEAL 61
>XP_006722261
          Length = 2092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DQAGLEQLA 9
            +QA L QLA
Sbjct: 1002 EQANLHQLA 1010
>XP_005258130
          Length = 2234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DQAGLEQLA 9
            +QA L QLA
Sbjct: 1145 EQANLHQLA 1153
>XP_006717286
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQAGLEQL 8
           ++AGL+QL
Sbjct: 227 ERAGLQQL 234
>XP_006717284
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQAGLEQL 8
           ++AGL+QL
Sbjct: 94  ERAGLQQL 101
>XP_006717283
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQAGLEQL 8
           ++AGL+QL
Sbjct: 219 ERAGLQQL 226
>XP_006717282
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQAGLEQL 8
           ++AGL+QL
Sbjct: 227 ERAGLQQL 234
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.126    0.317 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 523,627
Number of extensions: 685
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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