Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              20     509
NP_001035957                                                           20     509
XP_006721990                                                           20     509
XP_006721989                                                           20     509
XP_005258041                                                           20     509
XP_006721988                                                           20     509
XP_006721987                                                           20     509
XP_006721986                                                           20     509
XP_005258040                                                           20     509
XP_006721985                                                           20     509
NP_001005519                                                           17    2528
NP_775105                                                              17    2528
NP_001036148                                                           17    2528
NP_003963                                                              17    2528
XP_005270323                                                           17    2528
XP_005270322                                                           17    2528
XP_006715505                                                           17    2528
XP_006715504                                                           17    2528
XP_006715503                                                           17    2528
XP_006715502                                                           17    2528
NP_055859                                                              17    3301
NP_001269421                                                           17    3301
NP_473446                                                              17    4312
NP_055549                                                              17    4312
NP_689854                                                              17    4312
NP_061837                                                              17    4312
XP_005261199                                                           17    4312
XP_005261198                                                           17    4312
XP_006724079                                                           17    4312
XP_006724078                                                           17    4312
XP_006724077                                                           17    4312
XP_005261197                                                           17    4312
XP_005261196                                                           17    4312
XP_006719336                                                           17    4312
XP_006719335                                                           17    4312
NP_002847                                                              16    5631
NP_060356                                                              16    5631
XP_006713278                                                           16    5631
XP_005265318                                                           16    5631
NP_001005490                                                           16    7355
NP_001034450                                                           16    7355
NP_001278310                                                           16    7355
NP_055952                                                              16    7355
NP_150232                                                              16    7355
NP_001035700                                                           16    7355
NP_078856                                                              16    7355
NP_001919                                                              16    7355
XP_005275685                                                           16    7355
XP_005275547                                                           16    7355
XP_005275376                                                           16    7355
XP_005275252                                                           16    7355
XP_005275120                                                           16    7355
XP_005272964                                                           16    7355
XP_005274955                                                           16    7355
XP_005250906                                                           16    7355
XP_005249528                                                           16    7355
NP_001129575                                                           15    9605
NP_001273624                                                           15    9605
NP_001273623                                                           15    9605
NP_597705                                                              15    9605
NP_001129477                                                           15    9605
NP_001129478                                                           15    9605
NP_009114                                                              15    9605
NP_219501                                                              15    9605
NP_001026903                                                           15    9605
NP_000810                                                              15    9605
NP_001072                                                              15    9605
XP_006724053                                                           15    9605
XP_006724052                                                           15    9605
XP_005260998                                                           15    9605
XP_006724051                                                           15    9605
XP_005252817                                                           15    9605
NP_780294                                                              15    9605
NP_001004485                                                           15    9605
>NP_000258
          Length = 2818

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2591 DPKIQALLL 2599
>NP_001035957
          Length = 2839

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2612 DPKIQALLL 2620
>XP_006721990
          Length = 2823

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2622 DPKIQALLL 2630
>XP_006721989
          Length = 2823

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2622 DPKIQALLL 2630
>XP_005258041
          Length = 2836

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2591 DPKIQALLL 2599
>XP_006721988
          Length = 2846

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2601 DPKIQALLL 2609
>XP_006721987
          Length = 2849

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2622 DPKIQALLL 2630
>XP_006721986
          Length = 2854

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2609 DPKIQALLL 2617
>XP_005258040
          Length = 2857

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2612 DPKIQALLL 2620
>XP_006721985
          Length = 2867

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DPKIQ LLL
Sbjct: 2622 DPKIQALLL 2630
>NP_001005519
          Length = 312

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  DPKIQVLL 8
          DP++QVLL
Sbjct: 18 DPQLQVLL 25
>NP_775105
          Length = 1659

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DP+I +LLL
Sbjct: 1578 DPQINILLL 1586
>NP_001036148
          Length = 1683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DP+I +LLL
Sbjct: 1574 DPQINILLL 1582
>NP_003963
          Length = 1849

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    DPKIQVLLL 9
            DP I VLLL
Sbjct: 1696 DPSIDVLLL 1704
>XP_005270323
          Length = 1519

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    DPKIQVLLL 9
            DP I VLLL
Sbjct: 1366 DPSIDVLLL 1374
>XP_005270322
          Length = 1646

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    DPKIQVLLL 9
            DP I VLLL
Sbjct: 1493 DPSIDVLLL 1501
>XP_006715505
          Length = 1673

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DP+I +LLL
Sbjct: 1574 DPQINILLL 1582
>XP_006715504
          Length = 1683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DP+I +LLL
Sbjct: 1574 DPQINILLL 1582
>XP_006715503
          Length = 1707

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DP+I +LLL
Sbjct: 1574 DPQINILLL 1582
>XP_006715502
          Length = 1707

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DPKIQVLLL 9
            DP+I +LLL
Sbjct: 1574 DPQINILLL 1582
>NP_055859
          Length = 613

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   PKIQVLLL 9
           P++QVLLL
Sbjct: 512 PEVQVLLL 519
>NP_001269421
          Length = 230

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   PKIQVLLL 9
           PKI++LLL
Sbjct: 115 PKIKILLL 122
>NP_473446
          Length = 312

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DPKIQVLL 8
          DP +QVLL
Sbjct: 18 DPHLQVLL 25
>NP_055549
          Length = 303

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DPKIQVLL 8
           DP++Q++L
Sbjct: 193 DPRVQIVL 200
>NP_689854
          Length = 1835

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DPKIQVLLL 9
           DPKI  LLL
Sbjct: 196 DPKIITLLL 204
>NP_061837
          Length = 533

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DPKIQVLLL 9
           DP++Q LLL
Sbjct: 284 DPEMQCLLL 292
>XP_005261199
          Length = 429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DPKIQVLLL 9
           DP++Q LLL
Sbjct: 151 DPEMQCLLL 159
>XP_005261198
          Length = 533

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DPKIQVLLL 9
           DP++Q LLL
Sbjct: 284 DPEMQCLLL 292
>XP_006724079
          Length = 562

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DPKIQVLLL 9
           DP++Q LLL
Sbjct: 284 DPEMQCLLL 292
>XP_006724078
          Length = 562

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DPKIQVLLL 9
           DP++Q LLL
Sbjct: 284 DPEMQCLLL 292
>XP_006724077
          Length = 562

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DPKIQVLLL 9
           DP++Q LLL
Sbjct: 284 DPEMQCLLL 292
>XP_005261197
          Length = 562

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DPKIQVLLL 9
           DP++Q LLL
Sbjct: 284 DPEMQCLLL 292
>XP_005261196
          Length = 562

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DPKIQVLLL 9
           DP++Q LLL
Sbjct: 284 DPEMQCLLL 292
>XP_006719336
          Length = 1779

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DPKIQVLLL 9
           DPKI  LLL
Sbjct: 196 DPKIITLLL 204
>XP_006719335
          Length = 1793

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DPKIQVLLL 9
           DPKI  LLL
Sbjct: 196 DPKIITLLL 204
>NP_002847
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DPKIQVL 7
           DPK QVL
Sbjct: 409 DPKAQVL 415
>NP_060356
          Length = 1275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    DPKIQVLLL 9
            DPK Q LLL
Sbjct: 1212 DPKEQKLLL 1220
>XP_006713278
          Length = 1156

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    DPKIQVLLL 9
            DPK Q LLL
Sbjct: 1093 DPKEQKLLL 1101
>XP_005265318
          Length = 1274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    DPKIQVLLL 9
            DPK Q LLL
Sbjct: 1211 DPKEQKLLL 1219
>NP_001005490
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  DPKIQVLL 8
          DP++QV++
Sbjct: 18 DPQLQVII 25
>NP_001034450
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DPKIQVLL 8
           DP+++VLL
Sbjct: 363 DPQLRVLL 370
>NP_001278310
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DPKIQVLL 8
           DP+++VLL
Sbjct: 363 DPQLRVLL 370
>NP_055952
          Length = 821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DPKIQVL 7
           +PK+QVL
Sbjct: 112 EPKLQVL 118
>NP_150232
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>NP_001035700
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   DPKIQV 6
           DPK+Q+
Sbjct: 285 DPKVQI 290
>NP_078856
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   DPKIQV 6
           DPK+Q+
Sbjct: 336 DPKVQI 341
>NP_001919
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DPKIQVLL 8
          D K+QVLL
Sbjct: 73 DGKVQVLL 80
>XP_005275685
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>XP_005275547
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>XP_005275376
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>XP_005275252
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>XP_005275120
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>XP_005272964
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>XP_005274955
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>XP_005250906
          Length = 785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DPKIQVL 7
          +PK+QVL
Sbjct: 76 EPKLQVL 82
>XP_005249528
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           D K+QVLL
Sbjct: 152 DQKLQVLL 159
>NP_001129575
          Length = 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PKIQVL 7
           PK+QVL
Sbjct: 145 PKVQVL 150
>NP_001273624
          Length = 81

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DPKIQVLL 8
          DPK ++LL
Sbjct: 9  DPKKEILL 16
>NP_001273623
          Length = 120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DPKIQVLL 8
          DPK ++LL
Sbjct: 48 DPKKEILL 55
>NP_597705
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PKIQVL 7
           PK+QVL
Sbjct: 143 PKVQVL 148
>NP_001129477
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DP+ QV+L
Sbjct: 295 DPECQVIL 302
>NP_001129478
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DP+ QV+L
Sbjct: 295 DPECQVIL 302
>NP_009114
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DPKIQVL 7
           DP +QVL
Sbjct: 332 DPNLQVL 338
>NP_219501
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DPK ++LL
Sbjct: 124 DPKKEILL 131
>NP_001026903
          Length = 149

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DPKIQVLL 8
          DPK ++LL
Sbjct: 77 DPKKEILL 84
>NP_000810
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DP+ QV+L
Sbjct: 295 DPECQVIL 302
>NP_001072
          Length = 3623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    KIQVLLL 9
            K+QVLLL
Sbjct: 1365 KLQVLLL 1371
>XP_006724053
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DP+ QV+L
Sbjct: 295 DPECQVIL 302
>XP_006724052
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DP+ QV+L
Sbjct: 295 DPECQVIL 302
>XP_005260998
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DP+ QV+L
Sbjct: 295 DPECQVIL 302
>XP_006724051
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DP+ QV+L
Sbjct: 311 DPECQVIL 318
>XP_005252817
          Length = 812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DPKIQVL 7
           DP +QVL
Sbjct: 347 DPNLQVL 353
>NP_780294
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DPKIQVLL 8
           DP+ QV+L
Sbjct: 295 DPECQVIL 302
>NP_001004485
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  PKIQVLL 8
          PK+QV++
Sbjct: 21 PKVQVII 27
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.154    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 557,366
Number of extensions: 833
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package