Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245200                                                           20     299
NP_000240                                                              20     299
NP_001161089                                                           20     299
XP_005265218                                                           20     299
NP_001124456                                                           17    2528
NP_001124448                                                           17    2528
NP_003485                                                              17    2528
NP_001123927                                                           17    2528
NP_001124454                                                           17    2528
NP_001124452                                                           17    2528
NP_001124459                                                           17    2528
NP_001124455                                                           17    2528
NP_001124457                                                           17    2528
NP_001124450                                                           17    2528
NP_001124451                                                           17    2528
NP_001124449                                                           17    2528
NP_001124458                                                           17    2528
NP_001124453                                                           17    2528
NP_060009                                                              17    2528
XP_006721125                                                           17    2528
XP_005264642                                                           17    2528
XP_005264641                                                           17    2528
NP_001165349                                                           17    4312
NP_001165350                                                           17    4312
NP_005360                                                              17    4312
NP_001165347                                                           17    4312
XP_006724820                                                           17    4312
XP_005262471                                                           17    4312
XP_005262470                                                           17    4312
NP_001165348                                                           17    4312
NP_001093325                                                           17    4312
NP_078875                                                              16    5631
NP_001096078                                                           16    5631
NP_001005498                                                           16    5631
XP_005257727                                                           16    5631
XP_006722145                                                           16    5631
XP_006722144                                                           16    5631
XP_006722143                                                           16    5631
XP_006722142                                                           16    5631
XP_005257726                                                           16    5631
XP_005247178                                                           16    5631
NP_000526                                                              16    7355
NP_001258978                                                           16    7355
NP_057376                                                              16    7355
NP_003696                                                              16    7355
NP_001258629                                                           16    7355
XP_006715806                                                           16    7355
XP_006715805                                                           16    7355
XP_005246980                                                           16    7355
XP_005246141                                                           16    7355
XP_006712671                                                           16    7355
XP_005246139                                                           16    7355
NP_055488                                                              16    7355
NP_055543                                                              15    9605
NP_001192222                                                           15    9605
NP_001364                                                              15    9605
NP_001192223                                                           15    9605
NP_000712                                                              15    9605
NP_005784                                                              15    9605
XP_006724587                                                           15    9605
XP_005274689                                                           15    9605
XP_005264849                                                           15    9605
XP_005264846                                                           15    9605
XP_006711798                                                           15    9605
>NP_001245200
          Length = 687

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   DNIRSIFG 8
           DNIRSIFG
Sbjct: 214 DNIRSIFG 221
>NP_000240
          Length = 756

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   DNIRSIFG 8
           DNIRSIFG
Sbjct: 214 DNIRSIFG 221
>NP_001161089
          Length = 658

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   DNIRSIFG 8
           DNIRSIFG
Sbjct: 116 DNIRSIFG 123
>XP_005265218
          Length = 687

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   DNIRSIFG 8
           DNIRSIFG
Sbjct: 214 DNIRSIFG 221
>NP_001124456
          Length = 2088

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 401 DNVKQIFG 408
>NP_001124448
          Length = 2066

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 400 DNVKQIFG 407
>NP_003485
          Length = 2080

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 400 DNVKQIFG 407
>NP_001123927
          Length = 2081

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 401 DNVKQIFG 408
>NP_001124454
          Length = 2112

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 432 DNVKQIFG 439
>NP_001124452
          Length = 2097

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 431 DNVKQIFG 438
>NP_001124459
          Length = 2119

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 432 DNVKQIFG 439
>NP_001124455
          Length = 2102

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 401 DNVKQIFG 408
>NP_001124457
          Length = 2098

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 432 DNVKQIFG 439
>NP_001124450
          Length = 2101

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 400 DNVKQIFG 407
>NP_001124451
          Length = 2111

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 431 DNVKQIFG 438
>NP_001124449
          Length = 2087

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 400 DNVKQIFG 407
>NP_001124458
          Length = 2067

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 401 DNVKQIFG 408
>NP_001124453
          Length = 2118

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 431 DNVKQIFG 438
>NP_060009
          Length = 4116

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    DNIRSIF 7
            DNIRS+F
Sbjct: 2356 DNIRSLF 2362
>XP_006721125
          Length = 4070

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    DNIRSIF 7
            DNIRS+F
Sbjct: 2310 DNIRSLF 2316
>XP_005264642
          Length = 2132

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 431 DNVKQIFG 438
>XP_005264641
          Length = 2133

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           DN++ IFG
Sbjct: 432 DNVKQIFG 439
>NP_001165349
          Length = 860

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 408 ENIRSIF 414
>NP_001165350
          Length = 941

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 408 ENIRSIF 414
>NP_005360
          Length = 925

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 408 ENIRSIF 414
>NP_001165347
          Length = 1001

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 468 ENIRSIF 474
>XP_006724820
          Length = 902

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 369 ENIRSIF 375
>XP_005262471
          Length = 1005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 553 ENIRSIF 559
>XP_005262470
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 511 ENIRSIF 517
>NP_001165348
          Length = 821

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 369 ENIRSIF 375
>NP_001093325
          Length = 985

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DNIRSIF 7
           +NIRSIF
Sbjct: 468 ENIRSIF 474
>NP_078875
          Length = 856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DNIRSIFG 8
           DNI  IFG
Sbjct: 769 DNIAHIFG 776
>NP_001096078
          Length = 2263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DNIRSIFG 8
            +NI+ IFG
Sbjct: 1068 ENIKQIFG 1075
>NP_001005498
          Length = 827

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DNIRSIFG 8
           DNI  IFG
Sbjct: 740 DNIAHIFG 747
>XP_005257727
          Length = 827

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DNIRSIFG 8
           DNI  IFG
Sbjct: 740 DNIAHIFG 747
>XP_006722145
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DNIRSIFG 8
           DNI  IFG
Sbjct: 764 DNIAHIFG 771
>XP_006722144
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DNIRSIFG 8
           DNI  IFG
Sbjct: 764 DNIAHIFG 771
>XP_006722143
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DNIRSIFG 8
           DNI  IFG
Sbjct: 764 DNIAHIFG 771
>XP_006722142
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DNIRSIFG 8
           DNI  IFG
Sbjct: 764 DNIAHIFG 771
>XP_005257726
          Length = 856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DNIRSIFG 8
           DNI  IFG
Sbjct: 769 DNIAHIFG 776
>XP_005247178
          Length = 2263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DNIRSIFG 8
            +NI+ IFG
Sbjct: 1068 ENIKQIFG 1075
>NP_000526
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           +NI S+FG
Sbjct: 225 ENIGSVFG 232
>NP_001258978
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   NIRSIF 7
           NIRSIF
Sbjct: 285 NIRSIF 290
>NP_057376
          Length = 704

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   NIRSIF 7
           NIRSIF
Sbjct: 338 NIRSIF 343
>NP_003696
          Length = 678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           +N++ IFG
Sbjct: 109 ENVKEIFG 116
>NP_001258629
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NIRSIFG 8
           NIR+I+G
Sbjct: 383 NIRNIYG 389
>XP_006715806
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           +NI S+FG
Sbjct: 225 ENIGSVFG 232
>XP_006715805
          Length = 860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DNIRSIFG 8
           +NI S+FG
Sbjct: 223 ENIGSVFG 230
>XP_005246980
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DNIRSIFG 8
          +N++ IFG
Sbjct: 92 ENVKEIFG 99
>XP_005246141
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DNIRSIFGM 9
           D+I +IFG+
Sbjct: 133 DSITNIFGL 141
>XP_006712671
          Length = 540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DNIRSIFGM 9
           D+I +IFG+
Sbjct: 193 DSITNIFGL 201
>XP_005246139
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DNIRSIFGM 9
           D+I +IFG+
Sbjct: 277 DSITNIFGL 285
>NP_055488
          Length = 297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   NIRSIFGM 9
           N+R++FG+
Sbjct: 225 NMRALFGL 232
>NP_055543
          Length = 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DNIRSIFGM 9
           D+ RSIF M
Sbjct: 517 DSRRSIFNM 525
>NP_001192222
          Length = 2313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    DNIRSIFG 8
            +N RS FG
Sbjct: 1644 NNFRSFFG 1651
>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    DNIRSIF 7
            DN++S+F
Sbjct: 1662 DNLKSLF 1668
>NP_001192223
          Length = 2251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    DNIRSIFG 8
            +N RS FG
Sbjct: 1625 NNFRSFFG 1632
>NP_000712
          Length = 2270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    DNIRSIFG 8
            +N RS FG
Sbjct: 1644 NNFRSFFG 1651
>NP_005784
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DNIRSIFGM 9
           D+IR  FG+
Sbjct: 121 DSIRGSFGL 129
>XP_006724587
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DNIRSIFGM 9
           D+ RSIF M
Sbjct: 487 DSRRSIFNM 495
>XP_005274689
          Length = 1762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DNIRSIFGM 9
           D+ RSIF M
Sbjct: 517 DSRRSIFNM 525
>XP_005264849
          Length = 186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DNIRSIFGM 9
           D+IR  FG+
Sbjct: 113 DSIRGSFGL 121
>XP_005264846
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DNIRSIFGM 9
           D+IR  FG+
Sbjct: 271 DSIRGSFGL 279
>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    DNIRSIF 7
            DN++S+F
Sbjct: 1679 DNLKSLF 1685
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.151    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 379,018
Number of extensions: 624
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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