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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              19     869
NP_001239155                                                           17    4312
NP_006613                                                              17    4312
NP_001099001                                                           17    4312
NP_065870                                                              17    4312
NP_001156001                                                           17    4312
XP_005248807                                                           17    4312
XP_005248805                                                           17    4312
XP_005248804                                                           17    4312
XP_005248803                                                           17    4312
XP_005248802                                                           17    4312
XP_005248801                                                           17    4312
XP_005248800                                                           17    4312
NP_001129225                                                           16    5631
NP_001129224                                                           16    5631
NP_009196                                                              16    5631

>NP_115927
          Length = 1321

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DMKKSSVTA 9
           DMKKS VTA
Sbjct: 843 DMKKSPVTA 851



>NP_001239155
          Length = 671

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DMKKSSVT 8
           D+KK+S+T
Sbjct: 387 DLKKTSIT 394



>NP_006613
          Length = 685

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DMKKSSVT 8
           D+KK+S+T
Sbjct: 401 DLKKTSIT 408



>NP_001099001
          Length = 1319

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 688 DTKKSSIT 695



>NP_065870
          Length = 1302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 671 DTKKSSIT 678



>NP_001156001
          Length = 1515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 884 DTKKSSIT 891



>XP_005248807
          Length = 1182

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 551 DTKKSSIT 558



>XP_005248805
          Length = 1345

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 714 DTKKSSIT 721



>XP_005248804
          Length = 1378

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 747 DTKKSSIT 754



>XP_005248803
          Length = 1455

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 824 DTKKSSIT 831



>XP_005248802
          Length = 1515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 884 DTKKSSIT 891



>XP_005248801
          Length = 1541

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 910 DTKKSSIT 917



>XP_005248800
          Length = 1541

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DMKKSSVT 8
           D KKSS+T
Sbjct: 910 DTKKSSIT 917



>NP_001129225
          Length = 601

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DMKKSSVTA 9
           D KKS VTA
Sbjct: 278 DCKKSLVTA 286



>NP_001129224
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DMKKSSVTA 9
           D KKS VTA
Sbjct: 321 DCKKSLVTA 329



>NP_009196
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DMKKSSVTA 9
           D KKS VTA
Sbjct: 321 DCKKSLVTA 329



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.101    0.227 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 314,064
Number of extensions: 199
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)