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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              20     509
NP_001263689                                                           20     509
NP_001119584                                                           20     509
NP_001119586                                                           20     509
NP_001263625                                                           20     509
NP_001119590                                                           20     509
NP_001263690                                                           20     509
NP_001119585                                                           20     509
NP_001263624                                                           20     509
NP_001119588                                                           20     509
NP_001119587                                                           20     509
NP_001119589                                                           20     509
NP_001263627                                                           20     509
NP_001263628                                                           20     509
NP_001263626                                                           20     509
NP_064506                                                              17    3301
XP_005259653                                                           16    5631
NP_064555                                                              16    5631
NP_001269239                                                           16    7355
NP_001243398                                                           15    9605
NP_036462                                                              15    9605
NP_001243397                                                           15    9605
NP_055483                                                              15    9605
NP_038464                                                              15    9605
NP_995314                                                              15    9605
NP_612152                                                              15    9605
XP_005269721                                                           15    9605
XP_005250100                                                           15    9605
XP_006712264                                                           15    9605
XP_006712263                                                           15    9605
XP_005246254                                                           15    9605
XP_005246253                                                           15    9605
XP_005246252                                                           15    9605
XP_006711970                                                           15    9605
XP_006711969                                                           15    9605
XP_005246249                                                           15    9605
XP_006711968                                                           15    9605
XP_006711967                                                           15    9605

>NP_000537
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 160 MAIYKQSQ 167



>NP_001263689
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 121 MAIYKQSQ 128



>NP_001119584
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 160 MAIYKQSQ 167



>NP_001119586
          Length = 341

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 160 MAIYKQSQ 167



>NP_001263625
          Length = 302

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 121 MAIYKQSQ 128



>NP_001119590
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 121 MAIYKQSQ 128



>NP_001263690
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 121 MAIYKQSQ 128



>NP_001119585
          Length = 346

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 160 MAIYKQSQ 167



>NP_001263624
          Length = 307

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           MAIYKQSQ
Sbjct: 121 MAIYKQSQ 128



>NP_001119588
          Length = 209

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  MAIYKQSQ 9
          MAIYKQSQ
Sbjct: 28 MAIYKQSQ 35



>NP_001119587
          Length = 261

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  MAIYKQSQ 9
          MAIYKQSQ
Sbjct: 28 MAIYKQSQ 35



>NP_001119589
          Length = 214

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  MAIYKQSQ 9
          MAIYKQSQ
Sbjct: 28 MAIYKQSQ 35



>NP_001263627
          Length = 182

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2 MAIYKQSQ 9
         MAIYKQSQ
Sbjct: 1 MAIYKQSQ 8



>NP_001263628
          Length = 187

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2 MAIYKQSQ 9
         MAIYKQSQ
Sbjct: 1 MAIYKQSQ 8



>NP_001263626
          Length = 234

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2 MAIYKQSQ 9
         MAIYKQSQ
Sbjct: 1 MAIYKQSQ 8



>NP_064506
          Length = 1516

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  DMAIYKQSQ 9
          ++AIYKQ++
Sbjct: 73 ELAIYKQTE 81



>XP_005259653
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           ++IYKQ+Q
Sbjct: 153 LSIYKQTQ 160



>NP_064555
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MAIYKQSQ 9
           ++IYKQ+Q
Sbjct: 153 LSIYKQTQ 160



>NP_001269239
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DMAIYKQSQ 9
          DMA Y+Q +
Sbjct: 6  DMAAYQQEE 14



>NP_001243398
          Length = 1781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DMAIYKQSQ 9
           D+ ++KQ+Q
Sbjct: 400 DLDVFKQAQ 408



>NP_036462
          Length = 2073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DMAIYKQSQ 9
           D+ ++KQ+Q
Sbjct: 692 DLDVFKQAQ 700



>NP_001243397
          Length = 1890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DMAIYKQSQ 9
           D+ ++KQ+Q
Sbjct: 509 DLDVFKQAQ 517



>NP_055483
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DMAIYKQ 7
            +MAIYK+
Sbjct: 1580 EMAIYKK 1586



>NP_038464
          Length = 1128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    AIYKQS 8
            A+YKQS
Sbjct: 1118 AVYKQS 1123



>NP_995314
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    AIYKQS 8
            A+YKQS
Sbjct: 1124 AVYKQS 1129



>NP_612152
          Length = 2849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DMAIYKQSQ 9
           DM+ YK+++
Sbjct: 365 DMSTYKEAE 373



>XP_005269721
          Length = 2073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DMAIYKQSQ 9
           D+ ++KQ+Q
Sbjct: 692 DLDVFKQAQ 700



>XP_005250100
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IYKQSQ 9
           +YKQSQ
Sbjct: 285 LYKQSQ 290



>XP_006712264
          Length = 1126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    AIYKQS 8
            A+YKQS
Sbjct: 1116 AVYKQS 1121



>XP_006712263
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    AIYKQS 8
            A+YKQS
Sbjct: 1122 AVYKQS 1127



>XP_005246254
          Length = 947

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DMAIYKQ 7
           +MAIYK+
Sbjct: 578 EMAIYKK 584



>XP_005246253
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DMAIYKQ 7
           +MAIYK+
Sbjct: 669 EMAIYKK 675



>XP_005246252
          Length = 1850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DMAIYKQ 7
            +MAIYK+
Sbjct: 1481 EMAIYKK 1487



>XP_006711970
          Length = 1948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DMAIYKQ 7
            +MAIYK+
Sbjct: 1579 EMAIYKK 1585



>XP_006711969
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DMAIYKQ 7
            +MAIYK+
Sbjct: 1580 EMAIYKK 1586



>XP_005246249
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DMAIYKQ 7
            +MAIYK+
Sbjct: 1580 EMAIYKK 1586



>XP_006711968
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DMAIYKQ 7
            +MAIYK+
Sbjct: 1580 EMAIYKK 1586



>XP_006711967
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DMAIYKQ 7
            +MAIYK+
Sbjct: 1580 EMAIYKK 1586



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.120    0.306 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 384,460
Number of extensions: 513
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)