Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245202                                                           19     869
NP_001245200                                                           19     869
NP_001161091                                                           19     869
NP_000240                                                              19     869
NP_001161090                                                           19     869
NP_001161089                                                           19     869
NP_001245203                                                           19     869
XP_005265223                                                           19     869
XP_005265221                                                           19     869
XP_005265220                                                           19     869
XP_005265218                                                           19     869
NP_037398                                                              16    5631
NP_001120856                                                           16    5631
XP_006717870                                                           16    5631
XP_006717869                                                           16    5631
XP_005269774                                                           16    5631
XP_006717868                                                           16    5631
NP_001186795                                                           16    7355
NP_001269360                                                           16    7355
XP_005260809                                                           16    7355
XP_005260808                                                           16    7355
XP_005260807                                                           16    7355
NP_005728                                                              16    7355
NP_005493                                                              15    9605
NP_065920                                                              15    9605
XP_005251837                                                           15    9605
XP_005251835                                                           15    9605
XP_006717058                                                           15    9605
XP_005251833                                                           15    9605
XP_005251831                                                           15    9605
XP_005251830                                                           15    9605
XP_006715232                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
>NP_001245202
          Length = 515

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 343 DLAMLALDS 351
>NP_001245200
          Length = 687

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 584 DLAMLALDS 592
>NP_001161091
          Length = 515

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 343 DLAMLALDS 351
>NP_000240
          Length = 756

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 584 DLAMLALDS 592
>NP_001161090
          Length = 515

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 343 DLAMLALDS 351
>NP_001161089
          Length = 658

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 486 DLAMLALDS 494
>NP_001245203
          Length = 515

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 343 DLAMLALDS 351
>XP_005265223
          Length = 415

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 243 DLAMLALDS 251
>XP_005265221
          Length = 515

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 343 DLAMLALDS 351
>XP_005265220
          Length = 515

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 343 DLAMLALDS 351
>XP_005265218
          Length = 687

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           DL MLALDS
Sbjct: 515 DLAMLALDS 523
>NP_037398
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           +L+M ALDS
Sbjct: 795 ELIMSALDS 803
>NP_001120856
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           +L+M ALDS
Sbjct: 795 ELIMSALDS 803
>XP_006717870
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           +L+M ALDS
Sbjct: 534 ELIMSALDS 542
>XP_006717869
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           +L+M ALDS
Sbjct: 534 ELIMSALDS 542
>XP_005269774
          Length = 907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           +L+M ALDS
Sbjct: 807 ELIMSALDS 815
>XP_006717868
          Length = 907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DLVMLALDS 9
           +L+M ALDS
Sbjct: 807 ELIMSALDS 815
>NP_001186795
          Length = 1392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DLVMLALD 8
            DLV L+LD
Sbjct: 1193 DLVQLSLD 1200
>NP_001269360
          Length = 201

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LVMLALDS 9
          +VML LDS
Sbjct: 16 IVMLGLDS 23
>XP_005260809
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DLVMLALD 8
            DLV L+LD
Sbjct: 1633 DLVQLSLD 1640
>XP_005260808
          Length = 1872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DLVMLALD 8
            DLV L+LD
Sbjct: 1673 DLVQLSLD 1680
>XP_005260807
          Length = 1883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DLVMLALD 8
            DLV L+LD
Sbjct: 1684 DLVQLSLD 1691
>NP_005728
          Length = 192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LVMLALDS 9
          +VML LDS
Sbjct: 16 IVMLGLDS 23
>NP_005493
          Length = 2261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLVMLALDS 9
           DLV + LDS
Sbjct: 434 DLVRMLLDS 442
>NP_065920
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLVMLALD 8
           DLV+ ALD
Sbjct: 574 DLVLWALD 581
>XP_005251837
          Length = 1659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLVMLALDS 9
           DLV + LDS
Sbjct: 434 DLVRMLLDS 442
>XP_005251835
          Length = 2074

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLVMLALDS 9
           DLV + LDS
Sbjct: 434 DLVRMLLDS 442
>XP_006717058
          Length = 2100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLVMLALDS 9
           DLV + LDS
Sbjct: 434 DLVRMLLDS 442
>XP_005251833
          Length = 2203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLVMLALDS 9
           DLV + LDS
Sbjct: 374 DLVRMLLDS 382
>XP_005251831
          Length = 2263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLVMLALDS 9
           DLV + LDS
Sbjct: 434 DLVRMLLDS 442
>XP_005251830
          Length = 2263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLVMLALDS 9
           DLV + LDS
Sbjct: 434 DLVRMLLDS 442
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3500 IMLAIDS 3506
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3174 IMLAIDS 3180
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3500 IMLAIDS 3506
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3526 IMLAIDS 3532
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3533 IMLAIDS 3539
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3540 IMLAIDS 3546
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3573 IMLAIDS 3579
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3711 IMLAIDS 3717
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3616 IMLAIDS 3622
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3678 IMLAIDS 3684
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3711 IMLAIDS 3717
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3711 IMLAIDS 3717
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3690 IMLAIDS 3696
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3711 IMLAIDS 3717
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VMLALDS 9
            +MLA+DS
Sbjct: 3711 IMLAIDS 3717
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.140    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 272,533
Number of extensions: 383
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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