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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001073893                                                           18    1935
XP_006721547                                                           18    1935
XP_005256611                                                           18    1935
XP_005256609                                                           18    1935
XP_005256607                                                           18    1935
XP_005256608                                                           18    1935
XP_006721546                                                           18    1935
XP_005256606                                                           18    1935
XP_005269073                                                           17    4312
NP_001004334                                                           16    7355
NP_149072                                                              16    7355
NP_001180298                                                           16    7355

>NP_001073893
          Length = 1682

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DLRQSSVQR 9
           DLR+S VQR
Sbjct: 359 DLRESRVQR 367



>XP_006721547
          Length = 1638

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DLRQSSVQR 9
           DLR+S VQR
Sbjct: 359 DLRESRVQR 367



>XP_005256611
          Length = 1643

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DLRQSSVQR 9
           DLR+S VQR
Sbjct: 359 DLRESRVQR 367



>XP_005256609
          Length = 1682

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DLRQSSVQR 9
           DLR+S VQR
Sbjct: 359 DLRESRVQR 367



>XP_005256607
          Length = 1682

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DLRQSSVQR 9
           DLR+S VQR
Sbjct: 359 DLRESRVQR 367



>XP_005256608
          Length = 1682

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DLRQSSVQR 9
           DLR+S VQR
Sbjct: 359 DLRESRVQR 367



>XP_006721546
          Length = 1682

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DLRQSSVQR 9
           DLR+S VQR
Sbjct: 359 DLRESRVQR 367



>XP_005256606
          Length = 1682

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DLRQSSVQR 9
           DLR+S VQR
Sbjct: 359 DLRESRVQR 367



>XP_005269073
          Length = 173

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DLRQSSVQR 9
          DLR  S+QR
Sbjct: 40 DLRPKSIQR 48



>NP_001004334
          Length = 2367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLRQSSVQ 8
           D+R+SSV+
Sbjct: 117 DIRESSVE 124



>NP_149072
          Length = 2240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    DLRQSSVQR 9
            D+R++SV+R
Sbjct: 1451 DVRRNSVER 1459



>NP_001180298
          Length = 2240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    DLRQSSVQR 9
            D+R++SV+R
Sbjct: 1451 DVRRNSVER 1459



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.122    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 316,831
Number of extensions: 390
Number of successful extensions: 12
Number of sequences better than 10000.0: 12
Number of HSP's gapped: 12
Number of HSP's successfully gapped: 12
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)