Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           21     229
NP_000170                                                              21     229
NP_001268422                                                           21     229
NP_001268423                                                           21     229
XP_005264328                                                           21     229
NP_000537                                                              17    2528
NP_001263689                                                           17    2528
NP_001119584                                                           17    2528
NP_001119586                                                           17    2528
NP_001263625                                                           17    2528
NP_001119590                                                           17    2528
NP_001263690                                                           17    2528
NP_001119585                                                           17    2528
NP_001263624                                                           17    2528
NP_612357                                                              17    3301
NP_085135                                                              17    3301
XP_005258413                                                           17    3301
NP_976308                                                              17    3301
NP_006552                                                              16    7355
NP_060033                                                              16    7355
XP_006717432                                                           16    7355
XP_006713272                                                           16    7355
XP_005265295                                                           16    7355
NP_001273598                                                           15    9605
NP_001273599                                                           15    9605
NP_001273601                                                           15    9605
NP_001273600                                                           15    9605
NP_861522                                                              15    9605
NP_001273597                                                           15    9605
NP_660149                                                              15    9605
NP_001171134                                                           15    9605
NP_001229277                                                           15    9605
NP_060621                                                              15    9605
NP_001129477                                                           15    9605
NP_001171136                                                           15    9605
NP_001129478                                                           15    9605
NP_055160                                                              15    9605
NP_443179                                                              15    9605
NP_000810                                                              15    9605
XP_006724053                                                           15    9605
XP_006724052                                                           15    9605
XP_005260998                                                           15    9605
XP_006724051                                                           15    9605
XP_005266703                                                           15    9605
XP_005265784                                                           15    9605
XP_005265783                                                           15    9605
XP_005265781                                                           15    9605
XP_005265778                                                           15    9605
XP_005265639                                                           15    9605
XP_006713478                                                           15    9605
XP_006712674                                                           15    9605
XP_006712673                                                           15    9605
XP_006712672                                                           15    9605
XP_005246722                                                           15    9605
NP_001171135                                                           15    9605
>NP_001268421
          Length = 1230

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DLMLVPDKI 9
           DLM+VPDKI
Sbjct: 667 DLMVVPDKI 675
>NP_000170
          Length = 1360

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DLMLVPDKI 9
           DLM+VPDKI
Sbjct: 797 DLMVVPDKI 805
>NP_001268422
          Length = 1058

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DLMLVPDKI 9
           DLM+VPDKI
Sbjct: 495 DLMVVPDKI 503
>NP_001268423
          Length = 1058

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DLMLVPDKI 9
           DLM+VPDKI
Sbjct: 495 DLMVVPDKI 503
>XP_005264328
          Length = 1261

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DLMLVPDKI 9
           DLM+VPDKI
Sbjct: 698 DLMVVPDKI 706
>NP_000537
          Length = 393

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 42 DLMLSPDDI 50
>NP_001263689
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 3  DLMLSPDDI 11
>NP_001119584
          Length = 393

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 42 DLMLSPDDI 50
>NP_001119586
          Length = 341

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 42 DLMLSPDDI 50
>NP_001263625
          Length = 302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 3  DLMLSPDDI 11
>NP_001119590
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 3  DLMLSPDDI 11
>NP_001263690
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 3  DLMLSPDDI 11
>NP_001119585
          Length = 346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 42 DLMLSPDDI 50
>NP_001263624
          Length = 307

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DLML PD I
Sbjct: 3  DLMLSPDDI 11
>NP_612357
          Length = 352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLMLVPDKI 9
           +LML+P+K+
Sbjct: 153 ELMLLPEKL 161
>NP_085135
          Length = 2248

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DLMLVPDKI 9
            +L LVPDK+
Sbjct: 1561 ELPLVPDKL 1569
>XP_005258413
          Length = 2249

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DLMLVPDKI 9
            +L LVPDK+
Sbjct: 1562 ELPLVPDKL 1570
>NP_976308
          Length = 323

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  DLMLVPD 7
          DL+LVPD
Sbjct: 25 DLVLVPD 31
>NP_006552
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  MLVPDKI 9
          +LVPD+I
Sbjct: 19 LLVPDRI 25
>NP_060033
          Length = 739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L PD +
Sbjct: 186 DLLLQPDNL 194
>XP_006717432
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  MLVPDKI 9
          +LVPD+I
Sbjct: 19 LLVPDRI 25
>XP_006713272
          Length = 595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DLMLVPDKI 9
          DL+L PD +
Sbjct: 42 DLLLQPDNL 50
>XP_005265295
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L PD +
Sbjct: 158 DLLLQPDNL 166
>NP_001273598
          Length = 945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 419 DLLRVPDE 426
>NP_001273599
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLMLVPDK 8
          DL+ VPD+
Sbjct: 87 DLLRVPDE 94
>NP_001273601
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 572 DLLRVPDE 579
>NP_001273600
          Length = 857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 572 DLLRVPDE 579
>NP_861522
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 572 DLLRVPDE 579
>NP_001273597
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 472 DLLRVPDE 479
>NP_660149
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLMLVPDK 8
          DL+LVP +
Sbjct: 18 DLVLVPQR 25
>NP_001171134
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+ VPD +
Sbjct: 1638 DLLQVPDDL 1646
>NP_001229277
          Length = 104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LVPDKI 9
          LVPDK+
Sbjct: 44 LVPDKL 49
>NP_060621
          Length = 2472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+ VPD +
Sbjct: 1638 DLLQVPDDL 1646
>NP_001129477
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L P +I
Sbjct: 653 DLLLTPTRI 661
>NP_001171136
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+ VPD +
Sbjct: 1638 DLLQVPDDL 1646
>NP_001129478
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L P +I
Sbjct: 653 DLLLTPTRI 661
>NP_055160
          Length = 2279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+L PD I
Sbjct: 1398 DLLLPPDII 1406
>NP_443179
          Length = 2170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 3    MLVPDKI 9
            +++PDK+
Sbjct: 1266 LIIPDKV 1272
>NP_000810
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L P +I
Sbjct: 653 DLLLTPTRI 661
>XP_006724053
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L P +I
Sbjct: 653 DLLLTPTRI 661
>XP_006724052
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L P +I
Sbjct: 653 DLLLTPTRI 661
>XP_005260998
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L P +I
Sbjct: 653 DLLLTPTRI 661
>XP_006724051
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLMLVPDKI 9
           DL+L P +I
Sbjct: 669 DLLLTPTRI 677
>XP_005266703
          Length = 1501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 3   MLVPDKI 9
           +++PDK+
Sbjct: 597 LIIPDKV 603
>XP_005265784
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 195 DLLRVPDE 202
>XP_005265783
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 419 DLLRVPDE 426
>XP_005265781
          Length = 942

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 572 DLLRVPDE 579
>XP_005265778
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLMLVPDK 8
           DL+ VPD+
Sbjct: 572 DLLRVPDE 579
>XP_005265639
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLMLVPDK 8
          DL+LVP +
Sbjct: 46 DLVLVPQR 53
>XP_006713478
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLMLVPDK 8
          DL+LVP +
Sbjct: 78 DLVLVPQR 85
>XP_006712674
          Length = 2436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+ VPD +
Sbjct: 1602 DLLQVPDDL 1610
>XP_006712673
          Length = 2441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+ VPD +
Sbjct: 1607 DLLQVPDDL 1615
>XP_006712672
          Length = 2443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+ VPD +
Sbjct: 1609 DLLQVPDDL 1617
>XP_005246722
          Length = 2472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+ VPD +
Sbjct: 1638 DLLQVPDDL 1646
>NP_001171135
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DLMLVPDKI 9
            DL+ VPD +
Sbjct: 1638 DLLQVPDDL 1646
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.153    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 636,585
Number of extensions: 663
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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