Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           19     665
NP_000242                                                              19     665
XP_005264389                                                           19     665
NP_056263                                                              17    4312
XP_006717808                                                           17    4312
NP_008971                                                              16    7355
NP_001229338                                                           16    7355
NP_653333                                                              16    7355
NP_073588                                                              16    7355
XP_005258523                                                           16    7355
XP_005258522                                                           16    7355
XP_005258520                                                           16    7355
XP_005258521                                                           16    7355
XP_005258519                                                           16    7355
XP_005258518                                                           16    7355
XP_005258516                                                           16    7355
NP_689807                                                              15    9605
NP_001013725                                                           15    9605
NP_064608                                                              15    9605
XP_005254450                                                           15    9605
XP_005254449                                                           15    9605
XP_005254260                                                           15    9605
XP_005254259                                                           15    9605
>NP_001245210
          Length = 868

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LLVRQYRV 9
          LLVRQYRV
Sbjct: 27 LLVRQYRV 34
>NP_000242
          Length = 934

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LLVRQYRV 9
           LLVRQYRV
Sbjct: 93  LLVRQYRV 100
>XP_005264389
          Length = 921

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LLVRQYRV 9
           LLVRQYRV
Sbjct: 93  LLVRQYRV 100
>NP_056263
          Length = 203

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  DLLVRQYRV 9
          +LLVR++RV
Sbjct: 46 ELLVRKWRV 54
>XP_006717808
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DLLVRQYRV 9
           +LLVR++RV
Sbjct: 216 ELLVRKWRV 224
>NP_008971
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 588 DKLVRQY 594
>NP_001229338
          Length = 876

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DLLVRQYRV 9
          DLLV  YR+
Sbjct: 24 DLLVSTYRL 32
>NP_653333
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 488 DKLVRQY 494
>NP_073588
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DLLVRQYRV 9
          DLLV  YR+
Sbjct: 24 DLLVSTYRL 32
>XP_005258523
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 488 DKLVRQY 494
>XP_005258522
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 488 DKLVRQY 494
>XP_005258520
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 488 DKLVRQY 494
>XP_005258521
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 488 DKLVRQY 494
>XP_005258519
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 499 DKLVRQY 505
>XP_005258518
          Length = 777

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 499 DKLVRQY 505
>XP_005258516
          Length = 866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DLLVRQY 7
           D LVRQY
Sbjct: 588 DKLVRQY 594
>NP_689807
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DLLVRQY 7
           D+L+R+Y
Sbjct: 252 DILIRRY 258
>NP_001013725
          Length = 1649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DLLVRQYR 8
            DLL+ Q+R
Sbjct: 1353 DLLIPQFR 1360
>NP_064608
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LLVRQYRV 9
          +LVR++RV
Sbjct: 4  MLVRRFRV 11
>XP_005254450
          Length = 1505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DLLVRQYR 8
            DLL+ Q+R
Sbjct: 1353 DLLIPQFR 1360
>XP_005254449
          Length = 1626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DLLVRQYR 8
            DLL+ Q+R
Sbjct: 1353 DLLIPQFR 1360
>XP_005254260
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DLLVRQY 7
           D+L+R+Y
Sbjct: 178 DILIRRY 184
>XP_005254259
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DLLVRQY 7
           D+L+R+Y
Sbjct: 264 DILIRRY 270
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.155    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 441,112
Number of extensions: 859
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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