Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_056262                                                              17    2528
XP_005263454                                                           17    2528
XP_005263453                                                           17    2528
NP_001243415                                                           16    5631
NP_001243417                                                           16    5631
NP_004478                                                              16    5631
NP_001243416                                                           16    5631
NP_002461                                                              16    5631
NP_003790                                                              16    5631
NP_079216                                                              16    5631
XP_005258219                                                           16    5631
XP_006722424                                                           16    5631
XP_005258217                                                           16    5631
XP_006721591                                                           16    5631
XP_006716465                                                           16    5631
XP_005273707                                                           16    5631
XP_006713654                                                           16    5631
XP_006713653                                                           16    5631
XP_005247430                                                           16    5631
XP_005247429                                                           16    5631
XP_006713652                                                           16    5631
XP_006713651                                                           16    5631
XP_006713650                                                           16    5631
XP_005247428                                                           16    5631
NP_005947                                                              16    7355
NP_060051                                                              16    7355
NP_001123361                                                           16    7355
NP_001913                                                              16    7355
NP_004309                                                              15    9605
NP_057520                                                              15    9605
NP_009120                                                              15    9605
NP_001158222                                                           15    9605
NP_001010846                                                           15    9605
NP_005683                                                              15    9605
XP_005269220                                                           15    9605
XP_006716512                                                           15    9605
XP_005251307                                                           15    9605
XP_005251306                                                           15    9605
XP_005251305                                                           15    9605
XP_005251304                                                           15    9605
XP_005251303                                                           15    9605
XP_006716511                                                           15    9605
XP_005251301                                                           15    9605
XP_005251300                                                           15    9605
XP_005251299                                                           15    9605
XP_005251298                                                           15    9605
XP_005251297                                                           15    9605
XP_005251296                                                           15    9605
XP_005251295                                                           15    9605
XP_005251293                                                           15    9605
XP_005251292                                                           15    9605
XP_006715887                                                           15    9605
XP_005249988                                                           15    9605
XP_005244948                                                           15    9605
NP_006521                                                              15    9605
>NP_056262
          Length = 1602

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLAKKRSSF 9
            +LAKKR++F
Sbjct: 1282 ELAKKRAAF 1290
>XP_005263454
          Length = 1324

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLAKKRSSF 9
            +LAKKR++F
Sbjct: 1004 ELAKKRAAF 1012
>XP_005263453
          Length = 1613

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLAKKRSSF 9
            +LAKKR++F
Sbjct: 1293 ELAKKRAAF 1301
>NP_001243415
          Length = 3269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 536 DIANKRSS 543
>NP_001243417
          Length = 3184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 456 DIANKRSS 463
>NP_004478
          Length = 3259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 531 DIANKRSS 538
>NP_001243416
          Length = 3225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 497 DIANKRSS 504
>NP_002461
          Length = 1940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLAKK+ S
Sbjct: 204 DLAKKKDS 211
>NP_003790
          Length = 476

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DLAKKRSSF 9
          D+A+KR  F
Sbjct: 54 DIARKRKEF 62
>NP_079216
          Length = 1870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DLAKKRSSF 9
            +L KKR+SF
Sbjct: 1340 NLLKKRASF 1348
>XP_005258219
          Length = 476

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DLAKKRSSF 9
          D+A+KR  F
Sbjct: 54 DIARKRKEF 62
>XP_006722424
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DLAKKRSSF 9
          D+A+KR  F
Sbjct: 54 DIARKRKEF 62
>XP_005258217
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DLAKKRSSF 9
          D+A+KR  F
Sbjct: 54 DIARKRKEF 62
>XP_006721591
          Length = 1940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLAKK+ S
Sbjct: 204 DLAKKKDS 211
>XP_006716465
          Length = 1826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DLAKKRSSF 9
            +L KKR+SF
Sbjct: 1340 NLLKKRASF 1348
>XP_005273707
          Length = 1847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DLAKKRSSF 9
            +L KKR+SF
Sbjct: 1340 NLLKKRASF 1348
>XP_006713654
          Length = 3189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 456 DIANKRSS 463
>XP_006713653
          Length = 3223

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 495 DIANKRSS 502
>XP_005247430
          Length = 3228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 495 DIANKRSS 502
>XP_005247429
          Length = 3230

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 497 DIANKRSS 504
>XP_006713652
          Length = 3263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 530 DIANKRSS 537
>XP_006713651
          Length = 3264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 531 DIANKRSS 538
>XP_006713650
          Length = 3264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 536 DIANKRSS 543
>XP_005247428
          Length = 3269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           D+A KRSS
Sbjct: 536 DIANKRSS 543
>NP_005947
          Length = 935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DLAKKRSSF 9
           D AK+R+SF
Sbjct: 259 DEAKERASF 267
>NP_060051
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LAKKRSSF 9
           L K+RSSF
Sbjct: 232 LLKRRSSF 239
>NP_001123361
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DLAKKR 6
           DLAKKR
Sbjct: 146 DLAKKR 151
>NP_001913
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DLAKKR 6
           DLAKKR
Sbjct: 146 DLAKKR 151
>NP_004309
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 387 DLAEKRRS 394
>NP_057520
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLAKKRSS 8
           DL+++RSS
Sbjct: 322 DLSRRRSS 329
>NP_009120
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  DLAKKRSS 8
          DLAKK+++
Sbjct: 4  DLAKKKAA 11
>NP_001158222
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 358 DLAEKRRS 365
>NP_001010846
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LAKKRSS 8
           LAK+RSS
Sbjct: 273 LAKRRSS 279
>NP_005683
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  DLAKKRSS 8
          DLAKK+++
Sbjct: 4  DLAKKKAA 11
>XP_005269220
          Length = 173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DLAKKRSSF 9
           + AKK++SF
Sbjct: 130 EAAKKKTSF 138
>XP_006716512
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 192 DLAEKRRS 199
>XP_005251307
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 325 DLAEKRRS 332
>XP_005251306
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 330 DLAEKRRS 337
>XP_005251305
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 339 DLAEKRRS 346
>XP_005251304
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 340 DLAEKRRS 347
>XP_005251303
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 344 DLAEKRRS 351
>XP_006716511
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 344 DLAEKRRS 351
>XP_005251301
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 353 DLAEKRRS 360
>XP_005251300
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 359 DLAEKRRS 366
>XP_005251299
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 368 DLAEKRRS 375
>XP_005251298
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 372 DLAEKRRS 379
>XP_005251297
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 373 DLAEKRRS 380
>XP_005251296
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 383 DLAEKRRS 390
>XP_005251295
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 387 DLAEKRRS 394
>XP_005251293
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 401 DLAEKRRS 408
>XP_005251292
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLAKKRSS 8
           DLA+KR S
Sbjct: 402 DLAEKRRS 409
>XP_006715887
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  DLAKKRSS 8
          DLAKK+++
Sbjct: 4  DLAKKKAA 11
>XP_005249988
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  DLAKKRSS 8
          DLAKK+++
Sbjct: 4  DLAKKKAA 11
>XP_005244948
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LAKKRSS 8
           LAK+RSS
Sbjct: 273 LAKRRSS 279
>NP_006521
          Length = 227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DLAKKRSSF 9
           + AKK++SF
Sbjct: 184 EAAKKKTSF 192
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.125    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 404,651
Number of extensions: 627
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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