Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001026                                                              18    1935
NP_733751                                                              18    1935
XP_006716142                                                           18    1935
XP_005250088                                                           18    1935
XP_006716141                                                           18    1935
XP_005250085                                                           18    1935
XP_006716140                                                           18    1935
XP_005250084                                                           18    1935
XP_005250083                                                           18    1935
XP_005250082                                                           18    1935
XP_006711873                                                           18    1935
XP_006711872                                                           18    1935
XP_006711871                                                           18    1935
XP_006711870                                                           18    1935
XP_006711869                                                           18    1935
XP_006711868                                                           18    1935
XP_006711867                                                           18    1935
XP_006711866                                                           18    1935
XP_006711865                                                           18    1935
NP_001226                                                              17    3301
NP_001193943                                                           17    3301
XP_006718792                                                           17    3301
XP_006718791                                                           17    3301
XP_006718790                                                           17    3301
NP_001167558                                                           17    4312
NP_858045                                                              17    4312
NP_006525                                                              17    4312
NP_001167559                                                           17    4312
NP_004408                                                              17    4312
NP_001385                                                              17    4312
NP_476499                                                              17    4312
NP_003775                                                              17    4312
NP_001248760                                                           17    4312
NP_001248759                                                           17    4312
NP_001035237                                                           17    4312
XP_006722625                                                           17    4312
NP_001001670                                                           16    5631
NP_006149                                                              16    7355
NP_055244                                                              16    7355
NP_612429                                                              16    7355
XP_005267356                                                           16    7355
XP_005247419                                                           16    7355
NP_036320                                                              15    9605
NP_001189447                                                           15    9605
NP_003870                                                              15    9605
NP_001189446                                                           15    9605
NP_001189445                                                           15    9605
NP_001189448                                                           15    9605
NP_001120655                                                           15    9605
NP_001264125                                                           15    9605
NP_057102                                                              15    9605
NP_001120656                                                           15    9605
NP_054722                                                              15    9605
XP_005256326                                                           15    9605
XP_006716635                                                           15    9605
XP_005250999                                                           15    9605
XP_005250997                                                           15    9605
XP_005250996                                                           15    9605
XP_005250995                                                           15    9605
XP_005250994                                                           15    9605
XP_005250993                                                           15    9605
XP_005250992                                                           15    9605
XP_005250991                                                           15    9605
XP_005250990                                                           15    9605
XP_005250989                                                           15    9605
XP_005250988                                                           15    9605
XP_005250987                                                           15    9605
XP_005246995                                                           15    9605
XP_005246994                                                           15    9605
XP_005246992                                                           15    9605
XP_005246993                                                           15    9605
>NP_001026
          Length = 4967

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>NP_733751
          Length = 4911

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 775 DISKADVSS 783
>XP_006716142
          Length = 4927

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 776 DISKADVSS 784
>XP_005250088
          Length = 4928

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 776 DISKADVSS 784
>XP_006716141
          Length = 4959

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 776 DISKADVSS 784
>XP_005250085
          Length = 4979

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 776 DISKADVSS 784
>XP_006716140
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 776 DISKADVSS 784
>XP_005250084
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 776 DISKADVSS 784
>XP_005250083
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 775 DISKADVSS 783
>XP_005250082
          Length = 4983

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DKSKADVSS 9
           D SKADVSS
Sbjct: 776 DISKADVSS 784
>XP_006711873
          Length = 4954

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>XP_006711872
          Length = 2735

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>XP_006711871
          Length = 4906

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>XP_006711870
          Length = 4965

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>XP_006711869
          Length = 4973

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>XP_006711868
          Length = 4975

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>XP_006711867
          Length = 4977

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>XP_006711866
          Length = 4984

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>XP_006711865
          Length = 4985

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK KADV S
Sbjct: 318 DKEKADVKS 326
>NP_001226
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           DK+KAD+S
Sbjct: 331 DKNKADLS 338
>NP_001193943
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           DK+KAD+S
Sbjct: 331 DKNKADLS 338
>XP_006718792
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           DK+KAD+S
Sbjct: 331 DKNKADLS 338
>XP_006718791
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           DK+KAD+S
Sbjct: 331 DKNKADLS 338
>XP_006718790
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           DK+KAD+S
Sbjct: 331 DKNKADLS 338
>NP_001167558
          Length = 1423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  KADVSS
Sbjct: 94  DVQKADVSS 102
>NP_858045
          Length = 1424

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  KADVSS
Sbjct: 94  DVQKADVSS 102
>NP_006525
          Length = 1420

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  KADVSS
Sbjct: 94  DVQKADVSS 102
>NP_001167559
          Length = 1415

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  KADVSS
Sbjct: 94  DVQKADVSS 102
>NP_004408
          Length = 367

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  KAD+SS
Sbjct: 227 DNHKADISS 235
>NP_001385
          Length = 394

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  KAD+SS
Sbjct: 249 DNHKADISS 257
>NP_476499
          Length = 303

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  KAD+SS
Sbjct: 158 DNHKADISS 166
>NP_003775
          Length = 380

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           D+SKAD+S
Sbjct: 301 DESKADLS 308
>NP_001248760
          Length = 363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           D+SKAD+S
Sbjct: 284 DESKADLS 291
>NP_001248759
          Length = 380

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           D+SKAD+S
Sbjct: 301 DESKADLS 308
>NP_001035237
          Length = 380

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           D+SKAD+S
Sbjct: 301 DESKADLS 308
>XP_006722625
          Length = 380

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DKSKADVS 8
           D+SKAD+S
Sbjct: 301 DESKADLS 308
>NP_001001670
          Length = 1576

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           KSKAD+S+
Sbjct: 930 KSKADLST 937
>NP_006149
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           DK  AD+S+
Sbjct: 338 DKQNADISA 346
>NP_055244
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DKSKADVS 8
           DKS  DVS
Sbjct: 732 DKSNTDVS 739
>NP_612429
          Length = 5795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    KSKADVS 8
            K+KADVS
Sbjct: 4162 KAKADVS 4168
>XP_005267356
          Length = 5695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    KSKADVS 8
            K+KADVS
Sbjct: 4062 KAKADVS 4068
>XP_005247419
          Length = 1014

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DKSKADVS 8
           DKS  DVS
Sbjct: 762 DKSNTDVS 769
>NP_036320
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KSKADVSS 9
           K K+DVSS
Sbjct: 217 KRKSDVSS 224
>NP_001189447
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DKSKADVSS 9
          D  K+DVSS
Sbjct: 7  DLDKSDVSS 15
>NP_003870
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  K+DVSS
Sbjct: 103 DLDKSDVSS 111
>NP_001189446
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DKSKADVSS 9
          D  K+DVSS
Sbjct: 7  DLDKSDVSS 15
>NP_001189445
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  K+DVSS
Sbjct: 103 DLDKSDVSS 111
>NP_001189448
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DKSKADVSS 9
          D  K+DVSS
Sbjct: 7  DLDKSDVSS 15
>NP_001120655
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  K+DVSS
Sbjct: 103 DLDKSDVSS 111
>NP_001264125
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 295 KNEADISS 302
>NP_057102
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 321 KNEADISS 328
>NP_001120656
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  K+DVSS
Sbjct: 103 DLDKSDVSS 111
>NP_054722
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DKSKADVSS 9
          DK K+ VSS
Sbjct: 70 DKKKSKVSS 78
>XP_005256326
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DKSKADVSS 9
          DK K+ VSS
Sbjct: 70 DKKKSKVSS 78
>XP_006716635
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 321 KNEADISS 328
>XP_005250999
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 326 KNEADISS 333
>XP_005250997
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 217 KNEADISS 224
>XP_005250996
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 217 KNEADISS 224
>XP_005250995
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 326 KNEADISS 333
>XP_005250994
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 295 KNEADISS 302
>XP_005250993
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 296 KNEADISS 303
>XP_005250992
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 296 KNEADISS 303
>XP_005250991
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 321 KNEADISS 328
>XP_005250990
          Length = 1018

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 322 KNEADISS 329
>XP_005250989
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 325 KNEADISS 332
>XP_005250988
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 326 KNEADISS 333
>XP_005250987
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KSKADVSS 9
           K++AD+SS
Sbjct: 326 KNEADISS 333
>XP_005246995
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  K+DVSS
Sbjct: 103 DLDKSDVSS 111
>XP_005246994
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  K+DVSS
Sbjct: 103 DLDKSDVSS 111
>XP_005246992
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  K+DVSS
Sbjct: 103 DLDKSDVSS 111
>XP_005246993
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKSKADVSS 9
           D  K+DVSS
Sbjct: 103 DLDKSDVSS 111
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280   0.0992    0.222 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 417,704
Number of extensions: 895
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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