Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_000531                                                              17    4312
NP_001036188                                                           17    4312
NP_055641                                                              17    4312
NP_006026                                                              17    4312
NP_003598                                                              17    4312
XP_006723382                                                           17    4312
XP_006723381                                                           17    4312
XP_006723380                                                           17    4312
XP_005268287                                                           17    4312
XP_005268286                                                           17    4312
XP_005268285                                                           17    4312
XP_005268284                                                           17    4312
XP_006711900                                                           17    4312
XP_005273381                                                           17    4312
XP_005273380                                                           17    4312
XP_005273379                                                           17    4312
XP_006711899                                                           17    4312
XP_005273378                                                           17    4312
XP_005273377                                                           17    4312
XP_006711898                                                           17    4312
XP_006711897                                                           17    4312
XP_005273375                                                           17    4312
XP_005273374                                                           17    4312
NP_775915                                                              16    5631
NP_005529                                                              16    5631
NP_001070666                                                           16    5631
NP_076990                                                              16    5631
NP_061720                                                              16    5631
NP_001804                                                              16    7355
NP_001273663                                                           16    7355
XP_005272504                                                           16    7355
XP_006720704                                                           16    7355
NP_001708                                                              16    7355
NP_892006                                                              15    9605
NP_149062                                                              15    9605
NP_000353                                                              15    9605
NP_056372                                                              15    9605
NP_055454                                                              15    9605
NP_004679                                                              15    9605
NP_057535                                                              15    9605
NP_001137534                                                           15    9605
NP_001137533                                                           15    9605
XP_006715488                                                           15    9605
XP_006715487                                                           15    9605
XP_006715486                                                           15    9605
XP_006715485                                                           15    9605
XP_006715484                                                           15    9605
XP_006715483                                                           15    9605
XP_006715482                                                           15    9605
XP_006715481                                                           15    9605
XP_006715480                                                           15    9605
XP_006715479                                                           15    9605
XP_006715478                                                           15    9605
XP_006715477                                                           15    9605
XP_006715476                                                           15    9605
XP_006715475                                                           15    9605
XP_006715474                                                           15    9605
XP_006715473                                                           15    9605
XP_006715472                                                           15    9605
XP_006715471                                                           15    9605
XP_006715470                                                           15    9605
XP_005246998                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELSQRL
Sbjct: 951 EKLELSQRL 959
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELSQRL
Sbjct: 951 EKLELSQRL 959
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELSQRL
Sbjct: 951 EKLELSQRL 959
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELSQRL
Sbjct: 951 EKLELSQRL 959
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELSQRL
Sbjct: 951 EKLELSQRL 959
>NP_000531
          Length = 5038

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    DKLELSQRL 9
            D LELS+RL
Sbjct: 1648 DILELSERL 1656
>NP_001036188
          Length = 5033

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    DKLELSQRL 9
            D LELS+RL
Sbjct: 1648 DILELSERL 1656
>NP_055641
          Length = 1638

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>NP_006026
          Length = 1711

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 453 EKLELSRKL 461
>NP_003598
          Length = 1719

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_006723382
          Length = 5027

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    DKLELSQRL 9
            D LELS+RL
Sbjct: 1648 DILELSERL 1656
>XP_006723381
          Length = 5031

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    DKLELSQRL 9
            D LELS+RL
Sbjct: 1647 DILELSERL 1655
>XP_006723380
          Length = 5032

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    DKLELSQRL 9
            D LELS+RL
Sbjct: 1648 DILELSERL 1656
>XP_005268287
          Length = 1490

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 453 EKLELSRKL 461
>XP_005268286
          Length = 1685

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 453 EKLELSRKL 461
>XP_005268285
          Length = 1702

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 453 EKLELSRKL 461
>XP_005268284
          Length = 1728

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 453 EKLELSRKL 461
>XP_006711900
          Length = 993

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_005273381
          Length = 1732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_005273380
          Length = 1751

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_005273379
          Length = 1754

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_006711899
          Length = 1770

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_005273378
          Length = 1781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_005273377
          Length = 1794

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_006711898
          Length = 1797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_006711897
          Length = 1816

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_005273375
          Length = 1829

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>XP_005273374
          Length = 1832

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DKLELSQRL 9
           +KLELS++L
Sbjct: 454 EKLELSRKL 462
>NP_775915
          Length = 126

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DKLELSQRL 9
          DKLE+S  L
Sbjct: 35 DKLEISSNL 43
>NP_005529
          Length = 352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DKLELSQR 8
          DKL L+QR
Sbjct: 53 DKLHLTQR 60
>NP_001070666
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KLELSQRL 9
           +LEL+QRL
Sbjct: 279 RLELAQRL 286
>NP_076990
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KLELSQRL 9
           +LEL+QRL
Sbjct: 279 RLELAQRL 286
>NP_061720
          Length = 4024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKLELSQRL 9
           D +EL QRL
Sbjct: 621 DMIELEQRL 629
>NP_001804
          Length = 2701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    DKLELSQRL 9
            ++LEL+Q+L
Sbjct: 1180 ERLELAQKL 1188
>NP_001273663
          Length = 2580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    DKLELSQRL 9
            ++LEL+Q+L
Sbjct: 1155 ERLELAQKL 1163
>XP_005272504
          Length = 987

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKLELSQRL 9
           D +EL QRL
Sbjct: 663 DYMELQQRL 671
>XP_006720704
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKLELSQRL 9
           D +EL QRL
Sbjct: 668 DYMELQQRL 676
>NP_001708
          Length = 994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DKLELSQRL 9
           D +EL QRL
Sbjct: 670 DYMELQQRL 678
>NP_892006
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7325 DQLSLSQHL 7333
>NP_149062
          Length = 8749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7254 DQLSLSQHL 7262
>NP_000353
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DKLELSQR 8
           D+L LSQR
Sbjct: 125 DQLTLSQR 132
>NP_056372
          Length = 1954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    DKLELS 6
            DKLELS
Sbjct: 1649 DKLELS 1654
>NP_055454
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LELSQRL 9
            LEL+QRL
Sbjct: 1555 LELNQRL 1561
>NP_004679
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DKLELS 6
           DKLELS
Sbjct: 175 DKLELS 180
>NP_057535
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DKLELSQR 8
           DK+ LSQ+
Sbjct: 942 DKINLSQK 949
>NP_001137534
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DKLELSQR 8
           DK+ LSQ+
Sbjct: 942 DKINLSQK 949
>NP_001137533
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DKLELSQR 8
           DK+ LSQ+
Sbjct: 942 DKINLSQK 949
>XP_006715488
          Length = 8721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7337 DQLSLSQHL 7345
>XP_006715487
          Length = 8744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7337 DQLSLSQHL 7345
>XP_006715486
          Length = 8758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7337 DQLSLSQHL 7345
>XP_006715485
          Length = 8793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7284 DQLSLSQHL 7292
>XP_006715484
          Length = 8794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7285 DQLSLSQHL 7293
>XP_006715483
          Length = 8795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7286 DQLSLSQHL 7294
>XP_006715482
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7325 DQLSLSQHL 7333
>XP_006715481
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7290 DQLSLSQHL 7298
>XP_006715480
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7290 DQLSLSQHL 7298
>XP_006715479
          Length = 8804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7332 DQLSLSQHL 7340
>XP_006715478
          Length = 8809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7337 DQLSLSQHL 7345
>XP_006715477
          Length = 8822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7313 DQLSLSQHL 7321
>XP_006715476
          Length = 8823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7337 DQLSLSQHL 7345
>XP_006715475
          Length = 8827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7332 DQLSLSQHL 7340
>XP_006715474
          Length = 8829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7320 DQLSLSQHL 7328
>XP_006715473
          Length = 8832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7337 DQLSLSQHL 7345
>XP_006715472
          Length = 8839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7330 DQLSLSQHL 7338
>XP_006715471
          Length = 8842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7333 DQLSLSQHL 7341
>XP_006715470
          Length = 8846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DKLELSQRL 9
            D+L LSQ L
Sbjct: 7337 DQLSLSQHL 7345
>XP_005246998
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DKLELS 6
           DKLELS
Sbjct: 175 DKLELS 180
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.134    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,362
Number of extensions: 1136
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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