Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              20     509
NP_003335                                                              17    4312
NP_874356                                                              17    4312
NP_055553                                                              17    4312
NP_008959                                                              17    4312
XP_006726137                                                           17    4312
XP_006726047                                                           17    4312
XP_006726046                                                           17    4312
XP_006725957                                                           17    4312
XP_006725869                                                           17    4312
XP_006725867                                                           17    4312
XP_006725750                                                           17    4312
XP_006725748                                                           17    4312
XP_005257925                                                           17    4312
XP_005257924                                                           17    4312
XP_005257923                                                           17    4312
XP_005257922                                                           17    4312
XP_005257921                                                           17    4312
XP_006722263                                                           17    4312
XP_005257920                                                           17    4312
XP_006715041                                                           17    4312
XP_006715040                                                           17    4312
XP_006725533                                                           16    5631
NP_997201                                                              16    7355
XP_005262136                                                           16    7355
NP_004360                                                              15    9605
NP_476508                                                              15    9605
NP_476507                                                              15    9605
NP_510966                                                              15    9605
NP_001775                                                              15    9605
NP_001020331                                                           15    9605
NP_001008777                                                           15    9605
NP_710159                                                              15    9605
NP_001019554                                                           15    9605
NP_001138296                                                           15    9605
NP_006621                                                              15    9605
NP_694996                                                              15    9605
NP_619520                                                              15    9605
NP_055781                                                              15    9605
NP_001096078                                                           15    9605
NP_055718                                                              15    9605
NP_001265227                                                           15    9605
NP_001887                                                              15    9605
XP_006723038                                                           15    9605
XP_006723037                                                           15    9605
XP_006723036                                                           15    9605
XP_005260229                                                           15    9605
XP_005260228                                                           15    9605
XP_005260227                                                           15    9605
XP_005255856                                                           15    9605
XP_006719740                                                           15    9605
XP_006719739                                                           15    9605
XP_006719738                                                           15    9605
XP_005269272                                                           15    9605
XP_005273485                                                           15    9605
XP_005247178                                                           15    9605
XP_006713096                                                           15    9605
XP_006713095                                                           15    9605
XP_005246123                                                           15    9605
XP_005246122                                                           15    9605
XP_006712316                                                           15    9605
XP_005270453                                                           15    9605
XP_005270452                                                           15    9605
XP_005270451                                                           15    9605
NP_006836                                                              15    9605
>NP_004251
          Length = 1208

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DIVKLVDSM 9
           D+VKLVDSM
Sbjct: 988 DMVKLVDSM 996
>NP_003335
          Length = 183

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  DIVKLVDS 8
          D+VKL++S
Sbjct: 14 DVVKLIES 21
>NP_874356
          Length = 152

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  DIVKLVDS 8
          D+VKL++S
Sbjct: 14 DVVKLIES 21
>NP_055553
          Length = 1356

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           DIV+L+D +
Sbjct: 836 DIVRLIDGL 844
>NP_008959
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006726137
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006726047
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006726046
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006725957
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006725869
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006725867
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006725750
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006725748
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_005257925
          Length = 850

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           DIV+L+D +
Sbjct: 300 DIVRLIDGL 308
>XP_005257924
          Length = 1122

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           DIV+L+D +
Sbjct: 572 DIVRLIDGL 580
>XP_005257923
          Length = 1131

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           DIV+L+D +
Sbjct: 581 DIVRLIDGL 589
>XP_005257922
          Length = 1366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           DIV+L+D +
Sbjct: 846 DIVRLIDGL 854
>XP_005257921
          Length = 1370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           DIV+L+D +
Sbjct: 850 DIVRLIDGL 858
>XP_006722263
          Length = 1390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           DIV+L+D +
Sbjct: 840 DIVRLIDGL 848
>XP_005257920
          Length = 1390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           DIV+L+D +
Sbjct: 840 DIVRLIDGL 848
>XP_006715041
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006715040
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KLVDS+
Sbjct: 227 DLKKLVDSL 235
>XP_006725533
          Length = 425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           D+ KL+DS+
Sbjct: 227 DLKKLIDSL 235
>NP_997201
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DIVKLVD 7
           DI+K++D
Sbjct: 211 DIIKIID 217
>XP_005262136
          Length = 345

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DIVKLVD 7
           DI+K++D
Sbjct: 211 DIIKIID 217
>NP_004360
          Length = 3177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DIVKLVDS 8
          DI+ LVDS
Sbjct: 39 DIIFLVDS 46

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DIVKLVDS 8
            DIV L+DS
Sbjct: 1436 DIVFLIDS 1443
>NP_476508
          Length = 2971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DIVKLVDS 8
            DIV L+DS
Sbjct: 1230 DIVFLIDS 1237
>NP_476507
          Length = 2570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DIVKLVDS 8
           DIV L+DS
Sbjct: 829 DIVFLIDS 836
>NP_510966
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           +++KLVD +
Sbjct: 300 NVIKLVDEL 308
>NP_001775
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           +++KLVD +
Sbjct: 207 NVIKLVDEL 215
>NP_001020331
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           +++KLVD +
Sbjct: 251 NVIKLVDEL 259
>NP_001008777
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DIVKLVDSM 9
           D++ LVD +
Sbjct: 304 DVISLVDEL 312
>NP_710159
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DIVKLVDS 8
           D+VK +DS
Sbjct: 445 DVVKALDS 452
>NP_001019554
          Length = 2385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    DIVKLVD 7
            D+VK++D
Sbjct: 2209 DLVKIID 2215
>NP_001138296
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DIVKLVDSM 9
           D++K  DSM
Sbjct: 110 DLIKYEDSM 118
>NP_006621
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DIVKLVDSM 9
           D++K  DSM
Sbjct: 110 DLIKYEDSM 118
>NP_694996
          Length = 2526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DIVKLVDS 8
          D+V LVDS
Sbjct: 30 DVVFLVDS 37
>NP_619520
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DIVKLVDS 8
           DIV +VDS
Sbjct: 742 DIVHVVDS 749
>NP_055781
          Length = 1155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DIVKLVDS 8
           DIV +VDS
Sbjct: 703 DIVHVVDS 710
>NP_001096078
          Length = 2263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DIVKLVDS 8
          D+V LVDS
Sbjct: 27 DVVFLVDS 34
>NP_055718
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    DIVKLVD 7
            D+VK++D
Sbjct: 2187 DLVKIID 2193
>NP_001265227
          Length = 2614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DIVKLVDS 8
          D+V LVDS
Sbjct: 30 DVVFLVDS 37
>NP_001887
          Length = 350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVKLVDSM 9
           +I+KL+D++
Sbjct: 94  NIIKLIDTV 102
>XP_006723038
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DIVKLVDSM 9
           D++K  DSM
Sbjct: 98  DLIKYEDSM 106
>XP_006723037
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DIVKLVDSM 9
           D++K  DSM
Sbjct: 110 DLIKYEDSM 118
>XP_006723036
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DIVKLVDSM 9
           D++K  DSM
Sbjct: 110 DLIKYEDSM 118
>XP_005260229
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           +++KLVD +
Sbjct: 266 NVIKLVDEL 274
>XP_005260228
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           +++KLVD +
Sbjct: 310 NVIKLVDEL 318
>XP_005260227
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DIVKLVDSM 9
           +++KLVD +
Sbjct: 359 NVIKLVDEL 367
>XP_005255856
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVKLVDSM 9
           +I+KL+D++
Sbjct: 94  NIIKLIDTV 102
>XP_006719740
          Length = 1863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    DIVKLVD 7
            D+VK++D
Sbjct: 1687 DLVKIID 1693
>XP_006719739
          Length = 2306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    DIVKLVD 7
            D+VK++D
Sbjct: 2130 DLVKIID 2136
>XP_006719738
          Length = 2340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    DIVKLVD 7
            D+VK++D
Sbjct: 2164 DLVKIID 2170
>XP_005269272
          Length = 2356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    DIVKLVD 7
            D+VK++D
Sbjct: 2180 DLVKIID 2186
>XP_005273485
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DIVKLVDS 8
           D+VK +DS
Sbjct: 433 DVVKALDS 440
>XP_005247178
          Length = 2263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DIVKLVDS 8
          D+V LVDS
Sbjct: 27 DVVFLVDS 34
>XP_006713096
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DIVKLVDS 8
           DIV +VDS
Sbjct: 710 DIVHVVDS 717
>XP_006713095
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DIVKLVDS 8
           DIV +VDS
Sbjct: 770 DIVHVVDS 777
>XP_005246123
          Length = 2770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DIVKLVDS 8
            DIV L+DS
Sbjct: 1029 DIVFLIDS 1036
>XP_005246122
          Length = 2977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DIVKLVDS 8
          DI+ LVDS
Sbjct: 39 DIIFLVDS 46

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DIVKLVDS 8
            DIV L+DS
Sbjct: 1236 DIVFLIDS 1243
>XP_006712316
          Length = 3010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DIVKLVDS 8
          DI+ LVDS
Sbjct: 39 DIIFLVDS 46
>XP_005270453
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 1   DIVKLVD 7
           D++K++D
Sbjct: 390 DVIKMID 396
>XP_005270452
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 1   DIVKLVD 7
           D++K++D
Sbjct: 403 DVIKMID 409
>XP_005270451
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 1   DIVKLVD 7
           D++K++D
Sbjct: 435 DVIKMID 441
>NP_006836
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 1   DIVKLVD 7
           D++K++D
Sbjct: 444 DVIKMID 450
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.141    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 386,275
Number of extensions: 1011
Number of successful extensions: 67
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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