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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005179                                                              18    1135
XP_005245088                                                           17    3301
NP_056018                                                              17    3301
NP_056324                                                              17    4312
NP_078966                                                              16    5631
NP_060834                                                              16    5631
NP_149016                                                              16    7355
XP_005265460                                                           16    7355
NP_085128                                                              15    9605
NP_775099                                                              15    9605
NP_001019554                                                           15    9605
NP_056472                                                              15    9605
NP_004230                                                              15    9605
NP_055718                                                              15    9605
NP_005952                                                              15    9605
XP_005276320                                                           15    9605
XP_005276319                                                           15    9605
XP_005276318                                                           15    9605
XP_005276317                                                           15    9605
XP_006725067                                                           15    9605
XP_006725066                                                           15    9605
XP_006725065                                                           15    9605
XP_006725064                                                           15    9605
XP_005255623                                                           15    9605
XP_005268272                                                           15    9605
XP_005268270                                                           15    9605
XP_006720384                                                           15    9605
XP_006719740                                                           15    9605
XP_006719739                                                           15    9605
XP_006719738                                                           15    9605
XP_005269272                                                           15    9605
XP_005248451                                                           15    9605
XP_005248450                                                           15    9605
XP_005248449                                                           15    9605
XP_005248448                                                           15    9605
XP_006710226                                                           15    9605
NP_076936                                                              15    9605

>NP_005179
          Length = 906

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DISTASSSF 9
           DIS ASSSF
Sbjct: 792 DISNASSSF 800



>XP_005245088
          Length = 1435

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DISTASSSF 9
            D+ST+ SSF
Sbjct: 1104 DLSTSGSSF 1112



>NP_056018
          Length = 1461

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DISTASSSF 9
            D+ST+ SSF
Sbjct: 1130 DLSTSGSSF 1138



>NP_056324
          Length = 275

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DISTASSS 8
           D STASSS
Sbjct: 254 DFSTASSS 261



>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    DISTASSS 8
            D STASSS
Sbjct: 2921 DASTASSS 2928



>NP_060834
          Length = 802

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ISTASSSF 9
           ++TASSSF
Sbjct: 753 LTTASSSF 760



>NP_149016
          Length = 589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DISTASSS 8
           D STASSS
Sbjct: 354 DSSTASSS 361



>XP_005265460
          Length = 589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DISTASSS 8
           D STASSS
Sbjct: 354 DSSTASSS 361



>NP_085128
          Length = 2136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ISTASSSF 9
           +ST+SSS+
Sbjct: 569 VSTSSSSY 576



>NP_775099
          Length = 2595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DISTASSSF 9
            D+S +SS+F
Sbjct: 1697 DLSVSSSNF 1705



>NP_001019554
          Length = 2385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    STASSSF 9
            STA+SSF
Sbjct: 1059 STATSSF 1065



>NP_056472
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DISTASSSF 9
            D+S +SS+F
Sbjct: 1379 DLSVSSSNF 1387



>NP_004230
          Length = 1979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   STASSSF 9
           +TASSSF
Sbjct: 140 TTASSSF 146



>NP_055718
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    STASSSF 9
            STA+SSF
Sbjct: 1059 STATSSF 1065



>NP_005952
          Length = 2439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    STASSSF 9
            +TASSSF
Sbjct: 2081 ATASSSF 2087



>XP_005276320
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  DISTASSS 8
          DIS++SSS
Sbjct: 69 DISSSSSS 76




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 292 DISSSSSS 299



>XP_005276319
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 177 DISSSSSS 184




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 322 DISSSSSS 329




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 545 DISSSSSS 552



>XP_005276318
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_005276317
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_006725067
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 177 DISSSSSS 184




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 322 DISSSSSS 329




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 545 DISSSSSS 552



>XP_006725066
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_006725065
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_006725064
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 435 DISSSSSS 442



>XP_005255623
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   STASSSF 9
           STAS+SF
Sbjct: 402 STASTSF 408



>XP_005268272
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   STASSSF 9
           +TASSSF
Sbjct: 140 TTASSSF 146



>XP_005268270
          Length = 1950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   STASSSF 9
           +TASSSF
Sbjct: 140 TTASSSF 146



>XP_006720384
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   STASSSF 9
           +TASSSF
Sbjct: 139 TTASSSF 145



>XP_006719740
          Length = 1863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   STASSSF 9
           STA+SSF
Sbjct: 559 STATSSF 565



>XP_006719739
          Length = 2306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    STASSSF 9
            STA+SSF
Sbjct: 1002 STATSSF 1008



>XP_006719738
          Length = 2340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    STASSSF 9
            STA+SSF
Sbjct: 1036 STATSSF 1042



>XP_005269272
          Length = 2356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    STASSSF 9
            STA+SSF
Sbjct: 1059 STATSSF 1065



>XP_005248451
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  DISTASSS 8
          DIS++SSS
Sbjct: 69 DISSSSSS 76




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 292 DISSSSSS 299



>XP_005248450
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 177 DISSSSSS 184




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 322 DISSSSSS 329




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 545 DISSSSSS 552



>XP_005248449
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_005248448
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_006710226
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DISTASSS 8
           DIS++SSS
Sbjct: 244 DISSSSSS 251



>NP_076936
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   STASSSF 9
           STAS+SF
Sbjct: 402 STASTSF 408



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.105    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 309,588
Number of extensions: 649
Number of successful extensions: 57
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)