Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              21     229
XP_005271924                                                           21     229
XP_005271923                                                           21     229
NP_783863                                                              17    4312
NP_944489                                                              17    4312
XP_005269276                                                           17    4312
XP_006719749                                                           17    4312
XP_005269275                                                           17    4312
NP_644671                                                              16    5631
NP_009330                                                              16    5631
XP_005254203                                                           16    5631
XP_006712781                                                           16    5631
NP_055488                                                              16    5631
NP_001195                                                              16    7355
NP_036441                                                              16    7355
NP_573573                                                              16    7355
NP_872358                                                              16    7355
NP_055244                                                              16    7355
XP_005277989                                                           16    7355
XP_006718541                                                           16    7355
XP_006718540                                                           16    7355
XP_005277987                                                           16    7355
NP_001106177                                                           15    9605
NP_003897                                                              15    9605
NP_055528                                                              15    9605
NP_005732                                                              15    9605
XP_006724128                                                           15    9605
XP_006724127                                                           15    9605
XP_005261262                                                           15    9605
XP_005261261                                                           15    9605
XP_005261263                                                           15    9605
XP_005261260                                                           15    9605
XP_006720898                                                           15    9605
XP_006720897                                                           15    9605
XP_006720896                                                           15    9605
XP_006720895                                                           15    9605
XP_006720894                                                           15    9605
XP_005255088                                                           15    9605
NP_689808                                                              15    9605
NP_001968                                                              15    9605
>NP_001261
          Length = 1710

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DINNRNMIR 9
           DIN+RNMIR
Sbjct: 564 DINSRNMIR 572
>XP_005271924
          Length = 1710

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DINNRNMIR 9
           DIN+RNMIR
Sbjct: 564 DINSRNMIR 572
>XP_005271923
          Length = 1798

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DINNRNMIR 9
           DIN+RNMIR
Sbjct: 564 DINSRNMIR 572
>NP_783863
          Length = 1027

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           D+ N NM+R
Sbjct: 414 DLENENMMR 422
>NP_944489
          Length = 976

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           D+ N NM+R
Sbjct: 363 DLENENMMR 371
>XP_005269276
          Length = 925

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           D+ N NM+R
Sbjct: 311 DLENENMMR 319
>XP_006719749
          Length = 977

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           D+ N NM+R
Sbjct: 363 DLENENMMR 371
>XP_005269275
          Length = 1028

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           D+ N NM+R
Sbjct: 414 DLENENMMR 422
>NP_644671
          Length = 712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           D+N RN ++
Sbjct: 367 DVNERNTVK 375
>NP_009330
          Length = 750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           D+N RN ++
Sbjct: 367 DVNERNTVK 375
>XP_005254203
          Length = 848

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   INNRNMI 8
           INNRN +
Sbjct: 840 INNRNQV 846
>XP_006712781
          Length = 750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           D+N RN ++
Sbjct: 367 DVNERNTVK 375
>NP_055488
          Length = 297

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   INNRNM 7
           +NNRNM
Sbjct: 221 LNNRNM 226
>NP_001195
          Length = 1038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DINNRNMI 8
           D+N+RN++
Sbjct: 333 DLNSRNVL 340
>NP_036441
          Length = 1849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   DINNRNMIR 9
           ++NN N+++
Sbjct: 687 EVNNENVVK 695
>NP_573573
          Length = 1261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   DINNRNMIR 9
           ++NN N+++
Sbjct: 99  EVNNENVVK 107
>NP_872358
          Length = 895

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DINNRNMI 8
           D+NNR+ +
Sbjct: 164 DVNNRHKV 171
>NP_055244
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   INNRNM 7
           INNRN+
Sbjct: 443 INNRNL 448
>XP_005277989
          Length = 1470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   DINNRNMIR 9
           ++NN N+++
Sbjct: 308 EVNNENVVK 316
>XP_006718541
          Length = 1839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   DINNRNMIR 9
           ++NN N+++
Sbjct: 687 EVNNENVVK 695
>XP_006718540
          Length = 1842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   DINNRNMIR 9
           ++NN N+++
Sbjct: 687 EVNNENVVK 695
>XP_005277987
          Length = 1849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   DINNRNMIR 9
           ++NN N+++
Sbjct: 687 EVNNENVVK 695
>NP_001106177
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DINNRNMIR 9
           DI+NR M +
Sbjct: 242 DISNRKMAK 250
>NP_003897
          Length = 1980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNRNMIR 9
           INN NM +
Sbjct: 774 INNENMTK 781
>NP_055528
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   INNRNM 7
           INNRN+
Sbjct: 190 INNRNV 195
>NP_005732
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNRNMIR 9
           NN N+IR
Sbjct: 389 NNSNLIR 395
>XP_006724128
          Length = 1483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNRNMIR 9
           INN NM +
Sbjct: 277 INNENMTK 284
>XP_006724127
          Length = 1980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNRNMIR 9
           INN NM +
Sbjct: 774 INNENMTK 781
>XP_005261262
          Length = 1980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNRNMIR 9
           INN NM +
Sbjct: 774 INNENMTK 781
>XP_005261261
          Length = 1980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNRNMIR 9
           INN NM +
Sbjct: 774 INNENMTK 781
>XP_005261263
          Length = 1980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNRNMIR 9
           INN NM +
Sbjct: 774 INNENMTK 781
>XP_005261260
          Length = 1980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNRNMIR 9
           INN NM +
Sbjct: 774 INNENMTK 781
>XP_006720898
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNRNMIR 9
           NN N+IR
Sbjct: 185 NNSNLIR 191
>XP_006720897
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNRNMIR 9
           NN N+IR
Sbjct: 185 NNSNLIR 191
>XP_006720896
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNRNMIR 9
           NN N+IR
Sbjct: 304 NNSNLIR 310
>XP_006720895
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNRNMIR 9
           NN N+IR
Sbjct: 350 NNSNLIR 356
>XP_006720894
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNRNMIR 9
           NN N+IR
Sbjct: 376 NNSNLIR 382
>XP_005255088
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNRNMIR 9
           NN N+IR
Sbjct: 389 NNSNLIR 395
>NP_689808
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   DINNRN 6
           ++NNRN
Sbjct: 406 EVNNRN 411
>NP_001968
          Length = 957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNRNMIR 9
           +NNRN+ R
Sbjct: 884 LNNRNLGR 891
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.140    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 488,229
Number of extensions: 726
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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