Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              19     869
NP_001120972                                                           19     869
NP_115618                                                              19     869
XP_006716052                                                           19     869
XP_006716051                                                           19     869
XP_006713726                                                           19     869
NP_059984                                                              17    2528
XP_006724893                                                           17    2528
XP_005274763                                                           17    2528
XP_006724892                                                           17    2528
XP_005274762                                                           17    2528
NP_065861                                                              17    4312
XP_005267973                                                           17    4312
NP_954868                                                              16    5631
NP_954869                                                              16    5631
NP_001277153                                                           16    5631
NP_954870                                                              16    5631
NP_001265618                                                           16    5631
NP_954863                                                              16    5631
XP_005260859                                                           16    5631
XP_005260858                                                           16    5631
XP_005260857                                                           16    5631
XP_006723671                                                           16    5631
XP_006723670                                                           16    5631
XP_005260854                                                           16    5631
XP_006723669                                                           16    5631
XP_005264801                                                           16    5631
XP_006713174                                                           16    5631
XP_005264800                                                           16    5631
NP_570141                                                              16    5631
NP_071927                                                              16    5631
NP_065962                                                              16    7355
NP_061891                                                              16    7355
XP_005250744                                                           16    7355
XP_005250743                                                           16    7355
XP_006716234                                                           16    7355
XP_006714032                                                           16    7355
NP_001099013                                                           16    7355
NP_861440                                                              16    7355
NP_570118                                                              15    9605
NP_570116                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_001243779                                                           15    9605
NP_596869                                                              15    9605
NP_060829                                                              15    9605
XP_005246888                                                           15    9605
XP_006712788                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
XP_005264465                                                           15    9605
XP_005264464                                                           15    9605
NP_001019851                                                           15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605
>NP_000236
          Length = 1390

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           DILF VFAQ
Sbjct: 340 DILFGVFAQ 348
>NP_001120972
          Length = 1408

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           DILF VFAQ
Sbjct: 340 DILFGVFAQ 348
>NP_115618
          Length = 1896

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF VFAQ
Sbjct: 335 DVLFTVFAQ 343
>XP_006716052
          Length = 1409

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           DILF VFAQ
Sbjct: 359 DILFGVFAQ 367
>XP_006716051
          Length = 1427

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           DILF VFAQ
Sbjct: 359 DILFGVFAQ 367
>XP_006713726
          Length = 1910

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF VFAQ
Sbjct: 353 DVLFTVFAQ 361
>NP_059984
          Length = 1871

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF +F+Q
Sbjct: 315 DVLFTIFSQ 323
>XP_006724893
          Length = 1719

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF +F+Q
Sbjct: 315 DVLFTIFSQ 323
>XP_005274763
          Length = 1789

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF +F+Q
Sbjct: 233 DVLFTIFSQ 241
>XP_006724892
          Length = 1841

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF +F+Q
Sbjct: 315 DVLFTIFSQ 323
>XP_005274762
          Length = 1853

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF +F+Q
Sbjct: 315 DVLFTIFSQ 323
>NP_065861
          Length = 509

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DILFRVFA 8
           D+LF VFA
Sbjct: 300 DVLFDVFA 307
>XP_005267973
          Length = 537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DILFRVFA 8
           D+LF VFA
Sbjct: 328 DVLFDVFA 335
>NP_954868
          Length = 533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           D+L RVF +
Sbjct: 122 DVLLRVFVE 130
>NP_954869
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           D+L RVF +
Sbjct: 102 DVLLRVFVE 110
>NP_001277153
          Length = 413

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DILFRVFAQ 9
          D+L RVF +
Sbjct: 2  DVLLRVFVE 10
>NP_954870
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           D+L RVF +
Sbjct: 140 DVLLRVFVE 148
>NP_001265618
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LFRVFAQ 9
           LFR FAQ
Sbjct: 341 LFRAFAQ 347
>NP_954863
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           D+L RVF +
Sbjct: 122 DVLLRVFVE 130
>XP_005260859
          Length = 545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           ++ FR FAQ
Sbjct: 522 EVCFRTFAQ 530
>XP_005260858
          Length = 643

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           ++ FR FAQ
Sbjct: 522 EVCFRTFAQ 530
>XP_005260857
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           ++ FR FAQ
Sbjct: 522 EVCFRTFAQ 530
>XP_006723671
          Length = 684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           ++ FR FAQ
Sbjct: 522 EVCFRTFAQ 530
>XP_006723670
          Length = 711

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           ++ FR FAQ
Sbjct: 522 EVCFRTFAQ 530
>XP_005260854
          Length = 711

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           ++ FR FAQ
Sbjct: 522 EVCFRTFAQ 530
>XP_006723669
          Length = 718

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           ++ FR FAQ
Sbjct: 522 EVCFRTFAQ 530
>XP_005264801
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LFRVFAQ 9
           LFR FAQ
Sbjct: 341 LFRAFAQ 347
>XP_006713174
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LFRVFAQ 9
           LFR FAQ
Sbjct: 341 LFRAFAQ 347
>XP_005264800
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LFRVFAQ 9
           LFR FAQ
Sbjct: 341 LFRAFAQ 347
>NP_570141
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DILFRVFAQ 9
          D+L RVF +
Sbjct: 85 DVLLRVFVE 93
>NP_071927
          Length = 711

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DILFRVFAQ 9
           ++ FR FAQ
Sbjct: 522 EVCFRTFAQ 530
>NP_065962
          Length = 1894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF VF++
Sbjct: 333 DLLFTVFSK 341
>NP_061891
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ILFRVFAQ 9
           +LF++F+Q
Sbjct: 144 VLFQIFSQ 151
>XP_005250744
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF VF++
Sbjct: 333 DLLFTVFSK 341
>XP_005250743
          Length = 1894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF VF++
Sbjct: 333 DLLFTVFSK 341
>XP_006716234
          Length = 1894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF VF++
Sbjct: 333 DLLFTVFSK 341
>XP_006714032
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILFRVFA 8
           ILF+VFA
Sbjct: 412 ILFQVFA 418
>NP_001099013
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF VF++
Sbjct: 333 DLLFTVFSK 341
>NP_861440
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DILFRVFAQ 9
           D+LF VF++
Sbjct: 333 DLLFTVFSK 341
>NP_570118
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DILFRV 6
           D+LFRV
Sbjct: 180 DVLFRV 185
>NP_570116
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DILFRV 6
           D+LFRV
Sbjct: 180 DVLFRV 185
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 19945 EYFFRVFAE 19953
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 20070 EYFFRVFAE 20078
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 27369 EYFFRVFAE 27377
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 26442 EYFFRVFAE 26450
>NP_060829
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  DILFRV 6
          DILFR+
Sbjct: 8  DILFRI 13
>XP_005246888
          Length = 22663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 15682 EYFFRVFAE 15690
>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 17041 EYFFRVFAE 17049
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 26997 EYFFRVFAE 27005
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 28503 EYFFRVFAE 28511
>XP_005264465
          Length = 155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DILFRVFAQ 9
          +I F++F+Q
Sbjct: 41 EITFKIFSQ 49
>XP_005264464
          Length = 155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DILFRVFAQ 9
          +I F++F+Q
Sbjct: 41 EITFKIFSQ 49
>NP_001019851
          Length = 155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DILFRVFAQ 9
          +I F++F+Q
Sbjct: 41 EITFKIFSQ 49
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 29010 EYFFRVFAE 29018
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     DILFRVFAQ 9
             +  FRVFA+
Sbjct: 20137 EYFFRVFAE 20145
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.354    0.162    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 364,799
Number of extensions: 784
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)

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