Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     390
NP_004371                                                              17    3301
NP_001073315                                                           17    3301
XP_005255182                                                           17    3301
XP_006720911                                                           17    3301
XP_005255181                                                           17    3301
NP_056540                                                              17    4312
NP_620688                                                              16    5631
NP_079410                                                              16    5631
NP_055983                                                              16    5631
XP_005258735                                                           16    5631
XP_005258734                                                           16    5631
XP_005258733                                                           16    5631
XP_006723176                                                           16    5631
XP_005256233                                                           16    5631
XP_005256232                                                           16    5631
XP_005256231                                                           16    5631
XP_005256229                                                           16    5631
XP_005256228                                                           16    5631
XP_005256227                                                           16    5631
XP_006721346                                                           16    5631
XP_005256226                                                           16    5631
XP_006721345                                                           16    5631
XP_006721344                                                           16    5631
XP_006721343                                                           16    5631
XP_005256225                                                           16    5631
XP_005254929                                                           16    5631
NP_005155                                                              16    5631
NP_009186                                                              16    7355
NP_002838                                                              16    7355
NP_056128                                                              16    7355
NP_001185594                                                           16    7355
NP_001073876                                                           16    7355
XP_005271537                                                           16    7355
XP_005271535                                                           16    7355
XP_006718868                                                           16    7355
XP_006718823                                                           16    7355
XP_006716138                                                           16    7355
NP_570857                                                              16    7355
NP_570858                                                              16    7355
NP_001129386                                                           16    7355
YP_003024026                                                           16    7355
NP_059990                                                              15    9605
NP_055509                                                              15    9605
NP_001138792                                                           15    9605
XP_005266493                                                           15    9605
XP_005266492                                                           15    9605
XP_005272296                                                           15    9605
XP_006717400                                                           15    9605
XP_006717399                                                           15    9605
XP_005272294                                                           15    9605
>NP_115803
          Length = 1156

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DGQSQIMSG 9
           +GQSQIMSG
Sbjct: 223 NGQSQIMSG 231
>NP_004371
          Length = 2442

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GQSQIMSG 9
           GQ+Q+M+G
Sbjct: 204 GQAQVMNG 211
>NP_001073315
          Length = 2404

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GQSQIMSG 9
           GQ+Q+M+G
Sbjct: 204 GQAQVMNG 211
>XP_005255182
          Length = 2303

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GQSQIMSG 9
           GQ+Q+M+G
Sbjct: 204 GQAQVMNG 211
>XP_006720911
          Length = 2355

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GQSQIMSG 9
           GQ+Q+M+G
Sbjct: 204 GQAQVMNG 211
>XP_005255181
          Length = 2427

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GQSQIMSG 9
           GQ+Q+M+G
Sbjct: 204 GQAQVMNG 211
>NP_056540
          Length = 331

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DGQSQIMSG 9
          +GQSQ++ G
Sbjct: 2  NGQSQVLPG 10
>NP_620688
          Length = 1095

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSQIMSG 9
           G+S IMSG
Sbjct: 408 GRSHIMSG 415
>NP_079410
          Length = 2881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>NP_055983
          Length = 1303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GQSQIMSG 9
            GQS ++SG
Sbjct: 1138 GQSSVLSG 1145
>XP_005258735
          Length = 1254

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GQSQIMSG 9
            GQS ++SG
Sbjct: 1089 GQSSVLSG 1096
>XP_005258734
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GQSQIMSG 9
            GQS ++SG
Sbjct: 1097 GQSSVLSG 1104
>XP_005258733
          Length = 1267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GQSQIMSG 9
            GQS ++SG
Sbjct: 1102 GQSSVLSG 1109
>XP_006723176
          Length = 1303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GQSQIMSG 9
            GQS ++SG
Sbjct: 1138 GQSSVLSG 1145
>XP_005256233
          Length = 2391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1255 DGDGQLMEG 1263
>XP_005256232
          Length = 2424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1288 DGDGQLMEG 1296
>XP_005256231
          Length = 2573

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_005256229
          Length = 2881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_005256228
          Length = 2882

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_005256227
          Length = 2897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_006721346
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_005256226
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_006721345
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_006721344
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_006721343
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_005256225
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DGQSQIMSG 9
            DG  Q+M G
Sbjct: 1762 DGDGQLMEG 1770
>XP_005254929
          Length = 1122

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSQIMSG 9
           G+S IMSG
Sbjct: 408 GRSHIMSG 415
>NP_005155
          Length = 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQSQIM 7
           DGQ Q+M
Sbjct: 375 DGQKQVM 381
>NP_009186
          Length = 327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DGQSQIMSG 9
          DG+S ++SG
Sbjct: 15 DGRSGLLSG 23
>NP_002838
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DGQSQIMSG 9
           DG +++M+G
Sbjct: 330 DGMAELMAG 338
>NP_056128
          Length = 1544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    DGQSQIM 7
            D QSQIM
Sbjct: 1498 DSQSQIM 1504
>NP_001185594
          Length = 1525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    DGQSQIM 7
            D QSQIM
Sbjct: 1479 DSQSQIM 1485
>NP_001073876
          Length = 653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DGQSQIMSG 9
           DG+  ++SG
Sbjct: 258 DGEKHVLSG 266
>XP_005271537
          Length = 1441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    DGQSQIM 7
            D QSQIM
Sbjct: 1395 DSQSQIM 1401
>XP_005271535
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    DGQSQIM 7
            D QSQIM
Sbjct: 1458 DSQSQIM 1464
>XP_006718868
          Length = 1519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    DGQSQIM 7
            D QSQIM
Sbjct: 1473 DSQSQIM 1479
>XP_006718823
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   DGQSQIMSG 9
           DG+  ++SG
Sbjct: 616 DGEKHVLSG 624
>XP_006716138
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DGQSQIMSG 9
           DG +++M+G
Sbjct: 330 DGMAELMAG 338
>NP_570857
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DGQSQIMSG 9
           DG +++M+G
Sbjct: 313 DGMAELMAG 321
>NP_570858
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DGQSQIMSG 9
           DG +++M+G
Sbjct: 330 DGMAELMAG 338
>NP_001129386
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    DGQSQI 6
            DGQSQ+
Sbjct: 1261 DGQSQV 1266
>YP_003024026
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DGQSQIMSG 9
           +G+S+++SG
Sbjct: 202 EGESELVSG 210
>NP_059990
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQSQIMS 8
           DG+ QI+S
Sbjct: 526 DGRQQILS 533
>NP_055509
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQSQIM 7
           DGQ Q+M
Sbjct: 156 DGQRQLM 162
>NP_001138792
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQSQIM 7
           DGQ Q+M
Sbjct: 156 DGQRQLM 162
>XP_005266493
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQSQIMS 8
           DG+ QI+S
Sbjct: 526 DGRQQILS 533
>XP_005266492
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQSQIMS 8
           DG+ QI+S
Sbjct: 526 DGRQQILS 533
>XP_005272296
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQSQIM 7
           DGQ Q+M
Sbjct: 156 DGQRQLM 162
>XP_006717400
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQSQIM 7
           DGQ Q+M
Sbjct: 156 DGQRQLM 162
>XP_006717399
          Length = 1002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQSQIM 7
           DGQ Q+M
Sbjct: 265 DGQRQLM 271
>XP_005272294
          Length = 1060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQSQIM 7
           DGQ Q+M
Sbjct: 265 DGQRQLM 271
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.123    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 461,692
Number of extensions: 785
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package