Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              21     175
NP_002778                                                              18    1482
NP_112503                                                              17    3301
NP_000094                                                              17    3301
NP_001773                                                              17    3301
XP_006720469                                                           17    3301
XP_005254249                                                           17    3301
XP_005254248                                                           17    3301
XP_005254247                                                           17    3301
XP_005251689                                                           17    3301
XP_006716957                                                           17    3301
XP_006716956                                                           17    3301
NP_055904                                                              17    4312
NP_001124146                                                           17    4312
NP_001210                                                              17    4312
NP_001186601                                                           17    4312
NP_001186600                                                           17    4312
NP_690043                                                              17    4312
NP_000780                                                              17    4312
NP_001171528                                                           17    4312
XP_006721800                                                           17    4312
XP_005257167                                                           17    4312
XP_006715095                                                           17    4312
XP_006715094                                                           17    4312
XP_006715093                                                           17    4312
XP_006715092                                                           17    4312
NP_001138944                                                           16    5631
NP_065147                                                              16    5631
NP_955453                                                              16    5631
NP_653213                                                              16    5631
XP_006722454                                                           16    5631
XP_006722453                                                           16    5631
XP_006722452                                                           16    5631
XP_006722451                                                           16    5631
XP_006722450                                                           16    5631
XP_006722449                                                           16    5631
XP_006722448                                                           16    5631
XP_006722447                                                           16    5631
NP_543143                                                              16    5631
NP_065390                                                              16    7355
NP_775837                                                              16    7355
NP_008922                                                              16    7355
NP_001020026                                                           16    7355
XP_006724284                                                           16    7355
XP_006724283                                                           16    7355
XP_006724282                                                           16    7355
XP_005261537                                                           16    7355
XP_005264840                                                           16    7355
NP_000303                                                              15    9605
NP_055914                                                              15    9605
NP_056030                                                              15    9605
NP_002901                                                              15    9605
NP_001164639                                                           15    9605
NP_001164638                                                           15    9605
NP_689663                                                              15    9605
NP_112196                                                              15    9605
NP_001264992                                                           15    9605
NP_001189352                                                           15    9605
XP_005276413                                                           15    9605
XP_006722588                                                           15    9605
XP_006721544                                                           15    9605
XP_006721543                                                           15    9605
XP_006721542                                                           15    9605
XP_006721541                                                           15    9605
XP_006720462                                                           15    9605
XP_006720461                                                           15    9605
XP_005254223                                                           15    9605
XP_005252383                                                           15    9605
XP_006712696                                                           15    9605
XP_005263774                                                           15    9605
XP_005263773                                                           15    9605
XP_005263772                                                           15    9605
XP_006710547                                                           15    9605
XP_005276087                                                           15    9605
NP_001164637                                                           15    9605
NP_005504                                                              15    9605
>NP_115803
          Length = 1156

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DGQMTRENI 9
           DGQMT+ENI
Sbjct: 280 DGQMTQENI 288
>NP_002778
          Length = 234

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DGQMTRENI 9
           +GQMT +NI
Sbjct: 200 EGQMTEDNI 208
>NP_112503
          Length = 503

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQMTRENI 9
           G +TREN+
Sbjct: 289 GDLTRENV 296
>NP_000094
          Length = 503

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQMTRENI 9
           G +TREN+
Sbjct: 289 GDLTRENV 296
>NP_001773
          Length = 359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DGQMTRENI 9
          DG++T EN+
Sbjct: 34 DGEITYENV 42
>XP_006720469
          Length = 401

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQMTRENI 9
           G +TREN+
Sbjct: 187 GDLTRENV 194
>XP_005254249
          Length = 444

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQMTRENI 9
           G +TREN+
Sbjct: 230 GDLTRENV 237
>XP_005254248
          Length = 503

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQMTRENI 9
           G +TREN+
Sbjct: 289 GDLTRENV 296
>XP_005254247
          Length = 503

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQMTRENI 9
           G +TREN+
Sbjct: 289 GDLTRENV 296
>XP_005251689
          Length = 355

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DGQMTRENI 9
          DG++T EN+
Sbjct: 30 DGEITYENV 38
>XP_006716957
          Length = 362

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DGQMTRENI 9
          DG++T EN+
Sbjct: 30 DGEITYENV 38
>XP_006716956
          Length = 366

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DGQMTRENI 9
          DG++T EN+
Sbjct: 34 DGEITYENV 42
>NP_055904
          Length = 2517

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           D QMTRE
Sbjct: 824 DAQMTRE 830
>NP_001124146
          Length = 315

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGQMTRENI 9
           DG++T+E I
Sbjct: 282 DGKLTKEEI 290
>NP_001210
          Length = 315

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGQMTRENI 9
           DG++T+E I
Sbjct: 282 DGKLTKEEI 290
>NP_001186601
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGQMTRENI 9
           DG++T+E I
Sbjct: 290 DGKLTKEEI 298
>NP_001186600
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGQMTRENI 9
           DG++T+E I
Sbjct: 290 DGKLTKEEI 298
>NP_690043
          Length = 732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG +T+EN
Sbjct: 504 DGSITKEN 511
>NP_000780
          Length = 1306

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DGQMTREN 8
            DG +T+EN
Sbjct: 1078 DGSITKEN 1085
>NP_001171528
          Length = 691

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG +T+EN
Sbjct: 504 DGSITKEN 511
>XP_006721800
          Length = 616

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG +T+EN
Sbjct: 388 DGSITKEN 395
>XP_005257167
          Length = 1123

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG +T+EN
Sbjct: 895 DGSITKEN 902
>XP_006715095
          Length = 2046

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           D QMTRE
Sbjct: 353 DAQMTRE 359
>XP_006715094
          Length = 2407

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           D QMTRE
Sbjct: 714 DAQMTRE 720
>XP_006715093
          Length = 2459

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           D QMTRE
Sbjct: 766 DAQMTRE 772
>XP_006715092
          Length = 2490

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           D QMTRE
Sbjct: 824 DAQMTRE 830
>NP_001138944
          Length = 1114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DGQMTRE 7
          DGQ++RE
Sbjct: 21 DGQLSRE 27
>NP_065147
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQMTRENI 9
           G+MT EN+
Sbjct: 140 GEMTSENL 147
>NP_955453
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DGQMTRENI 9
           DGQ+ R N+
Sbjct: 173 DGQLKRRNM 181
>NP_653213
          Length = 2211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DGQMTRE 7
            DGQ++RE
Sbjct: 1132 DGQLSRE 1138
>XP_006722454
          Length = 1144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DGQMTRE 7
          DGQ++RE
Sbjct: 65 DGQLSRE 71
>XP_006722453
          Length = 1162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DGQMTRE 7
          DGQ++RE
Sbjct: 21 DGQLSRE 27
>XP_006722452
          Length = 1162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DGQMTRE 7
          DGQ++RE
Sbjct: 21 DGQLSRE 27
>XP_006722451
          Length = 1206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DGQMTRE 7
          DGQ++RE
Sbjct: 65 DGQLSRE 71
>XP_006722450
          Length = 1249

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGQMTRE 7
           DGQ++RE
Sbjct: 163 DGQLSRE 169
>XP_006722449
          Length = 1256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGQMTRE 7
           DGQ++RE
Sbjct: 163 DGQLSRE 169
>XP_006722448
          Length = 1304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGQMTRE 7
           DGQ++RE
Sbjct: 163 DGQLSRE 169
>XP_006722447
          Length = 1933

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGQMTRE 7
           DGQ++RE
Sbjct: 854 DGQLSRE 860
>NP_543143
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DGQMTRENI 9
           DGQ+ R N+
Sbjct: 173 DGQLKRRNM 181
>NP_065390
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQMTRENI 9
           GQ+T EN+
Sbjct: 270 GQLTLENL 277
>NP_775837
          Length = 2151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DGQMTRENI 9
            DG+M  EN+
Sbjct: 1266 DGEMLCENV 1274
>NP_008922
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MTRENI 9
         MTREN+
Sbjct: 1 MTRENV 6
>NP_001020026
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MTRENI 9
         MTREN+
Sbjct: 1 MTRENV 6
>XP_006724284
          Length = 1989

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DGQMTRENI 9
            DG+M  EN+
Sbjct: 1104 DGEMLCENV 1112
>XP_006724283
          Length = 2151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DGQMTRENI 9
            DG+M  EN+
Sbjct: 1266 DGEMLCENV 1274
>XP_006724282
          Length = 2151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DGQMTRENI 9
            DG+M  EN+
Sbjct: 1266 DGEMLCENV 1274
>XP_005261537
          Length = 2151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DGQMTRENI 9
            DG+M  EN+
Sbjct: 1266 DGEMLCENV 1274
>XP_005264840
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MTRENI 9
         MTREN+
Sbjct: 1 MTRENV 6
>NP_000303
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DGQMTR 6
           DG+MTR
Sbjct: 214 DGKMTR 219
>NP_055914
          Length = 1202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 96  DGKTTRED 103
>NP_056030
          Length = 1673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 129 DGKTTRED 136
>NP_002901
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DGQMTRENI 9
           DGQ   EN+
Sbjct: 231 DGQAVLENV 239
>NP_001164639
          Length = 1201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 119 DGKTTRED 126
>NP_001164638
          Length = 1241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 119 DGKTTRED 126
>NP_689663
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           DGQ TR+
Sbjct: 292 DGQRTRQ 298
>NP_112196
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   DGQMTREN 8
           DG M  EN
Sbjct: 499 DGNMVEEN 506
>NP_001264992
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DGQMTREN 8
           D Q T+EN
Sbjct: 871 DSQKTKEN 878
>NP_001189352
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   DGQMTREN 8
           DG M  EN
Sbjct: 343 DGNMVEEN 350
>XP_005276413
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MTRENI 9
         MTREN+
Sbjct: 4 MTRENL 9
>XP_006722588
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DGQMTREN 8
           D Q T+EN
Sbjct: 871 DSQKTKEN 878
>XP_006721544
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 96  DGKTTRED 103
>XP_006721543
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 96  DGKTTRED 103
>XP_006721542
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 96  DGKTTRED 103
>XP_006721541
          Length = 1207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 96  DGKTTRED 103
>XP_006720462
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           DGQ TR+
Sbjct: 292 DGQRTRQ 298
>XP_006720461
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           DGQ TR+
Sbjct: 292 DGQRTRQ 298
>XP_005254223
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DGQMTRE 7
           DGQ TR+
Sbjct: 301 DGQRTRQ 307
>XP_005252383
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MTRENI 9
         MTREN+
Sbjct: 4 MTRENL 9
>XP_006712696
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DGQMTR 6
           DG+MTR
Sbjct: 222 DGKMTR 227
>XP_005263774
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DGQMTR 6
           DG+MTR
Sbjct: 235 DGKMTR 240
>XP_005263773
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DGQMTR 6
           DG+MTR
Sbjct: 269 DGKMTR 274
>XP_005263772
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DGQMTR 6
           DG+MTR
Sbjct: 275 DGKMTR 280
>XP_006710547
          Length = 198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 129 DGKTTRED 136
>XP_005276087
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MTRENI 9
         MTREN+
Sbjct: 4 MTRENL 9
>NP_001164637
          Length = 1197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGQMTREN 8
           DG+ TRE+
Sbjct: 98  DGKTTRED 105
>NP_005504
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  DGQMTREN 8
          DG+ TR N
Sbjct: 83 DGKTTRHN 90
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.129    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,308
Number of extensions: 1217
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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