Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     869
XP_006718908                                                           19     869
XP_005271621                                                           19     869
XP_006718907                                                           19     869
XP_006718906                                                           19     869
XP_005271619                                                           19     869
XP_005271618                                                           19     869
NP_071349                                                              17    4312
XP_005257625                                                           17    4312
XP_005257624                                                           17    4312
NP_149100                                                              16    5631
NP_001193849                                                           16    5631
XP_005264686                                                           16    5631
NP_001136272                                                           16    7355
NP_001264994                                                           16    7355
NP_001264995                                                           16    7355
NP_001264996                                                           16    7355
NP_001264993                                                           16    7355
NP_694997                                                              16    7355
NP_055144                                                              16    7355
XP_005273935                                                           16    7355
XP_005273934                                                           16    7355
XP_005273933                                                           16    7355
XP_006718554                                                           16    7355
XP_006718553                                                           16    7355
XP_006718552                                                           16    7355
XP_006715531                                                           16    7355
XP_006715530                                                           16    7355
NP_056529                                                              15    9605
NP_001264671                                                           15    9605
NP_063938                                                              15    9605
XP_005264490                                                           15    9605
YP_003024034                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGIMVKLFV 9
            DGIMVKL V
Sbjct: 1641 DGIMVKLVV 1649
>XP_006718908
          Length = 1708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           DGIMVKL V
Sbjct: 293 DGIMVKLVV 301
>XP_005271621
          Length = 2708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGIMVKLFV 9
            DGIMVKL V
Sbjct: 1293 DGIMVKLVV 1301
>XP_006718907
          Length = 3050

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGIMVKLFV 9
            DGIMVKL V
Sbjct: 1635 DGIMVKLVV 1643
>XP_006718906
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGIMVKLFV 9
            DGIMVKL V
Sbjct: 1641 DGIMVKLVV 1649
>XP_005271619
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGIMVKLFV 9
            DGIMVKL V
Sbjct: 1641 DGIMVKLVV 1649
>XP_005271618
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGIMVKLFV 9
            DGIMVKL V
Sbjct: 1641 DGIMVKLVV 1649
>NP_071349
          Length = 1292

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGIMVKLF 8
           +GIMVK F
Sbjct: 971 EGIMVKTF 978
>XP_005257625
          Length = 1268

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGIMVKLF 8
           +GIMVK F
Sbjct: 947 EGIMVKTF 954
>XP_005257624
          Length = 1293

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGIMVKLF 8
           +GIMVK F
Sbjct: 972 EGIMVKTF 979
>NP_149100
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GIMVKLF 8
           G+MVKL+
Sbjct: 693 GVMVKLY 699
>NP_001193849
          Length = 484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           DG+ +KLF+
Sbjct: 204 DGLTLKLFL 212
>XP_005264686
          Length = 703

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GIMVKLF 8
           G+MVKL+
Sbjct: 613 GVMVKLY 619
>NP_001136272
          Length = 3144

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    DGIMVKLFV 9
            DG  ++LF+
Sbjct: 1931 DGFFIQLFI 1939
>NP_001264994
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIMVKLFV 9
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_001264995
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIMVKLFV 9
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_001264996
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIMVKLFV 9
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_001264993
          Length = 1194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIMVKLFV 9
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_694997
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           +GI VK+F+
Sbjct: 212 EGISVKMFL 220
>NP_055144
          Length = 1401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   GIMVKLF 8
           G+++KLF
Sbjct: 503 GVLIKLF 509
>XP_005273935
          Length = 897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           +GI VK+F+
Sbjct: 213 EGISVKMFL 221
>XP_005273934
          Length = 917

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           +GI VK+F+
Sbjct: 212 EGISVKMFL 220
>XP_005273933
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           +GI VK+F+
Sbjct: 213 EGISVKMFL 221
>XP_006718554
          Length = 946

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           +GI VK+F+
Sbjct: 262 EGISVKMFL 270
>XP_006718553
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           +GI VK+F+
Sbjct: 263 EGISVKMFL 271
>XP_006718552
          Length = 968

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGIMVKLFV 9
           +GI VK+F+
Sbjct: 263 EGISVKMFL 271
>XP_006715531
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIMVKLFV 9
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>XP_006715530
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIMVKLFV 9
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_056529
          Length = 103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GIMVKLFV 9
          G MVKL+V
Sbjct: 21 GKMVKLYV 28
>NP_001264671
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DGIMVKLF 8
           DG+ VK F
Sbjct: 409 DGLSVKFF 416
>NP_063938
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DGIMVKLF 8
           DG+ VK F
Sbjct: 484 DGLSVKFF 491
>XP_005264490
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DGIMVKLF 8
           DG+ VK F
Sbjct: 426 DGLSVKFF 433
>YP_003024034
          Length = 98

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DGIMVKLFV 9
          +G+M+ LF+
Sbjct: 34 EGMMLSLFI 42
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.161    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 326,889
Number of extensions: 522
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package