Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     299
XP_005262424                                                           20     299
NP_061119                                                              19     869
NP_613258                                                              19     869
NP_613075                                                              19     869
NP_001035248                                                           19     869
NP_004884                                                              19     869
XP_005272192                                                           19     869
XP_005272191                                                           19     869
XP_005272189                                                           19     869
NP_000382                                                              17    2528
NP_004317                                                              17    4312
NP_001010986                                                           17    4312
NP_775965                                                              17    4312
XP_006724816                                                           17    4312
XP_006724815                                                           17    4312
XP_006724814                                                           17    4312
XP_005262462                                                           17    4312
XP_005277475                                                           17    4312
XP_005277474                                                           17    4312
XP_006711546                                                           17    4312
XP_005273028                                                           17    4312
NP_000304                                                              16    5631
NP_005397                                                              16    5631
NP_001167522                                                           16    5631
NP_006021                                                              16    5631
NP_001278030                                                           16    5631
NP_001005505                                                           16    5631
NP_001138890                                                           16    5631
NP_004451                                                              16    5631
NP_001239586                                                           16    5631
XP_006724234                                                           16    5631
XP_005261462                                                           16    5631
XP_005247683                                                           16    5631
XP_005265638                                                           16    5631
XP_006713052                                                           16    5631
XP_006713051                                                           16    5631
NP_060644                                                              16    5631
NP_001005284                                                           16    5631
NP_006493                                                              16    7355
NP_005132                                                              16    7355
NP_001171670                                                           16    7355
NP_057036                                                              16    7355
XP_006715181                                                           16    7355
XP_005249243                                                           16    7355
NP_060791                                                              16    7355
NP_000129                                                              15    9605
NP_004685                                                              15    9605
NP_001167637                                                           15    9605
NP_699196                                                              15    9605
NP_055401                                                              15    9605
NP_997254                                                              15    9605
XP_006722232                                                           15    9605
XP_005257846                                                           15    9605
XP_005252508                                                           15    9605
XP_006717511                                                           15    9605
XP_005252507                                                           15    9605
XP_005248199                                                           15    9605
XP_005248198                                                           15    9605
XP_005248197                                                           15    9605
XP_005248196                                                           15    9605
>NP_722576
          Length = 3080

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DGFTVLSNR 9
            DGFTVLS+R
Sbjct: 1476 DGFTVLSDR 1484
>XP_005262424
          Length = 2875

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DGFTVLSNR 9
            DGFTVLS+R
Sbjct: 1271 DGFTVLSDR 1279
>NP_061119
          Length = 372

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DGFTVLSNR 9
           DGFT+LS++
Sbjct: 181 DGFTILSSK 189
>NP_613258
          Length = 372

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           DGFTVLS +
Sbjct: 181 DGFTVLSTK 189
>NP_613075
          Length = 369

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           DGFTVLS +
Sbjct: 181 DGFTVLSTK 189
>NP_001035248
          Length = 371

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           DGFTVLS +
Sbjct: 180 DGFTVLSTK 188
>NP_004884
          Length = 371

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           DGFTVLS +
Sbjct: 180 DGFTVLSTK 188
>XP_005272192
          Length = 198

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           DGFTVLS +
Sbjct: 180 DGFTVLSTK 188
>XP_005272191
          Length = 199

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           DGFTVLS +
Sbjct: 181 DGFTVLSTK 189
>XP_005272189
          Length = 368

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           DGFTVLS +
Sbjct: 180 DGFTVLSTK 188
>NP_000382
          Length = 563

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           DG+ V+SNR
Sbjct: 457 DGYWVVSNR 465
>NP_004317
          Length = 1426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    DGFTVLSN 8
            D FTVL N
Sbjct: 1202 DSFTVLGN 1209
>NP_001010986
          Length = 1119

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GFTVLSNR 9
           GFT L NR
Sbjct: 512 GFTFLGNR 519
>NP_775965
          Length = 1132

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GFTVLSNR 9
           GFT L NR
Sbjct: 512 GFTFLGNR 519
>XP_006724816
          Length = 1105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GFTVLSNR 9
           GFT L NR
Sbjct: 509 GFTFLGNR 516
>XP_006724815
          Length = 1105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GFTVLSNR 9
           GFT L NR
Sbjct: 509 GFTFLGNR 516
>XP_006724814
          Length = 1116

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GFTVLSNR 9
           GFT L NR
Sbjct: 509 GFTFLGNR 516
>XP_005262462
          Length = 1129

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GFTVLSNR 9
           GFT L NR
Sbjct: 509 GFTFLGNR 516
>XP_005277475
          Length = 1352

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    DGFTVLSN 8
            D FTVL N
Sbjct: 1128 DSFTVLGN 1135
>XP_005277474
          Length = 1414

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    DGFTVLSN 8
            D FTVL N
Sbjct: 1190 DSFTVLGN 1197
>XP_006711546
          Length = 1426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    DGFTVLSN 8
            D FTVL N
Sbjct: 1202 DSFTVLGN 1209
>XP_005273028
          Length = 1426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    DGFTVLSN 8
            D FTVL N
Sbjct: 1202 DSFTVLGN 1209
>NP_000304
          Length = 676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           +GF +LSN+
Sbjct: 188 NGFVMLSNK 196
>NP_005397
          Length = 1354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GFTVLSNR 9
           GFT  SNR
Sbjct: 396 GFTYYSNR 403
>NP_001167522
          Length = 1150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GFTVLSNR 9
           GF VLSN+
Sbjct: 897 GFLVLSNQ 904
>NP_006021
          Length = 1143

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GFTVLSNR 9
           GF VLSN+
Sbjct: 890 GFLVLSNQ 897
>NP_001278030
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GFTVLSNR 9
           GF VLSN+
Sbjct: 821 GFLVLSNQ 828
>NP_001005505
          Length = 1145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GFTVLSNR 9
           GF VLSN+
Sbjct: 890 GFLVLSNQ 897
>NP_001138890
          Length = 2481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    DGFTVLSN 8
            +GF+++SN
Sbjct: 2057 EGFSIISN 2064
>NP_004451
          Length = 760

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FTVLSNR 9
          +T+LSNR
Sbjct: 87 YTILSNR 93
>NP_001239586
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGFTVLSN 8
           D FTV+SN
Sbjct: 187 DKFTVVSN 194
>XP_006724234
          Length = 2363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    DGFTVLSN 8
            +GF+++SN
Sbjct: 1939 EGFSIISN 1946
>XP_005261462
          Length = 2473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    DGFTVLSN 8
            +GF+++SN
Sbjct: 2049 EGFSIISN 2056
>XP_005247683
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DGFTVLSNR 9
           +GF +LSN+
Sbjct: 220 NGFVMLSNK 228
>XP_005265638
          Length = 1144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GFTVLSNR 9
           GF VLSN+
Sbjct: 891 GFLVLSNQ 898
>XP_006713052
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGFTVLSN 8
           D FTV+SN
Sbjct: 187 DKFTVVSN 194
>XP_006713051
          Length = 618

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGFTVLSN 8
           D FTV+SN
Sbjct: 187 DKFTVVSN 194
>NP_060644
          Length = 1059

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGFTVLSN 8
           +GFTVL N
Sbjct: 259 NGFTVLVN 266
>NP_001005284
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GFTVLSN 8
           GFTVLS+
Sbjct: 219 GFTVLSS 225
>NP_006493
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DGFTVLSN 8
           D FTV+ N
Sbjct: 398 DAFTVIKN 405
>NP_005132
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GFTVLSNR 9
           G+TV+ NR
Sbjct: 278 GWTVIQNR 285
>NP_001171670
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GFTVLSNR 9
           G+TV+ NR
Sbjct: 219 GWTVIQNR 226
>NP_057036
          Length = 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  DGFTVLS 7
          D FTVLS
Sbjct: 21 DSFTVLS 27
>XP_006715181
          Length = 561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DGFTVLSN 8
           D FTV+ N
Sbjct: 246 DAFTVIKN 253
>XP_005249243
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DGFTVLSN 8
           D FTV+ N
Sbjct: 336 DAFTVIKN 343
>NP_060791
          Length = 353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FTVLSNR 9
           FT+L NR
Sbjct: 208 FTILDNR 214
>NP_000129
          Length = 2871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FTVLSNR 9
           FTV+SN+
Sbjct: 187 FTVISNQ 193
>NP_004685
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  TVLSNR 9
          TVLSNR
Sbjct: 82 TVLSNR 87
>NP_001167637
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  TVLSNR 9
          TVLSNR
Sbjct: 82 TVLSNR 87
>NP_699196
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DGFTVLSNR 9
           D FT+  NR
Sbjct: 557 DRFTICGNR 565
>NP_055401
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TVLSNR 9
           TVLSNR
Sbjct: 365 TVLSNR 370
>NP_997254
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DGFTVLSNR 9
           D FTV++ R
Sbjct: 821 DDFTVINRR 829
>XP_006722232
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  TVLSNR 9
          TVLSNR
Sbjct: 82 TVLSNR 87
>XP_005257846
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  TVLSNR 9
          TVLSNR
Sbjct: 82 TVLSNR 87
>XP_005252508
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DGFTVLSNR 9
           D FTV++ R
Sbjct: 821 DDFTVINRR 829
>XP_006717511
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DGFTVLSNR 9
           D FTV++ R
Sbjct: 821 DDFTVINRR 829
>XP_005252507
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DGFTVLSNR 9
           D FTV++ R
Sbjct: 821 DDFTVINRR 829
>XP_005248199
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DGFTVLSNR 9
           D FT+  NR
Sbjct: 416 DRFTICGNR 424
>XP_005248198
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DGFTVLSNR 9
           D FT+  NR
Sbjct: 416 DRFTICGNR 424
>XP_005248197
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DGFTVLSNR 9
           D FT+  NR
Sbjct: 431 DRFTICGNR 439
>XP_005248196
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   DGFTVLSNR 9
           D FT+  NR
Sbjct: 431 DRFTICGNR 439
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.140    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 488,528
Number of extensions: 842
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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