Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           20     299
NP_001277143                                                           20     299
NP_001077383                                                           20     299
NP_001320                                                              20     299
NP_073713                                                              20     299
XP_005269629                                                           20     299
XP_005269628                                                           20     299
XP_005269627                                                           20     299
XP_005269626                                                           20     299
XP_006717706                                                           20     299
XP_005269625                                                           20     299
XP_005269624                                                           20     299
XP_006717705                                                           20     299
XP_005269622                                                           20     299
XP_005269621                                                           20     299
XP_006717704                                                           20     299
XP_005269619                                                           20     299
XP_005269618                                                           20     299
NP_001319                                                              20     390
NP_001012632                                                           20     390
XP_005272320                                                           20     390
XP_005272319                                                           20     390
XP_005272318                                                           20     390
NP_001010939                                                           18    1935
NP_003557                                                              18    1935
XP_006719694                                                           18    1935
XP_005269599                                                           18    1935
XP_006717698                                                           18    1935
NP_006311                                                              17    2528
NP_997244                                                              17    4312
NP_001156372                                                           16    5631
NP_001273330                                                           16    5631
NP_660359                                                              16    5631
NP_001033056                                                           16    7355
NP_000446                                                              16    7355
NP_000023                                                              16    7355
NP_055712                                                              16    7355
NP_001138837                                                           16    7355
NP_001033057                                                           16    7355
NP_660149                                                              16    7355
NP_001263280                                                           16    7355
NP_001254500                                                           16    7355
NP_001254501                                                           16    7355
NP_060891                                                              16    7355
XP_005262052                                                           16    7355
XP_005259675                                                           16    7355
XP_005259674                                                           16    7355
XP_005257223                                                           16    7355
XP_006721837                                                           16    7355
XP_005265639                                                           16    7355
XP_006713478                                                           16    7355
NP_000072                                                              15    9605
NP_001804                                                              15    9605
NP_001138498                                                           15    9605
NP_005503                                                              15    9605
NP_001122394                                                           15    9605
NP_001273663                                                           15    9605
NP_694996                                                              15    9605
NP_006853                                                              15    9605
NP_001077434                                                           15    9605
NP_001077433                                                           15    9605
NP_001077432                                                           15    9605
NP_001265227                                                           15    9605
NP_079040                                                              15    9605
XP_005273960                                                           15    9605
XP_005273959                                                           15    9605
XP_005273954                                                           15    9605
XP_005273087                                                           15    9605
XP_006711794                                                           15    9605
XP_005273086                                                           15    9605
XP_005273084                                                           15    9605
XP_005244911                                                           15    9605
XP_005244910                                                           15    9605
NP_068747                                                              15    9605
>NP_001277144
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>NP_001277143
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>NP_001077383
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>NP_001320
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>NP_073713
          Length = 985

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 795 DFTIKQMRQ 803
>XP_005269629
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269628
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269627
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269626
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_006717706
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269625
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269624
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_006717705
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269622
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269621
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_006717704
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269619
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>XP_005269618
          Length = 445

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF IKQMRQ
Sbjct: 255 DFTIKQMRQ 263
>NP_001319
          Length = 440

 Score = 20.0 bits (40), Expect =   390
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF +KQMRQ
Sbjct: 249 DFTVKQMRQ 257
>NP_001012632
          Length = 429

 Score = 20.0 bits (40), Expect =   390
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF +KQMRQ
Sbjct: 238 DFTVKQMRQ 246
>XP_005272320
          Length = 430

 Score = 20.0 bits (40), Expect =   390
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF +KQMRQ
Sbjct: 238 DFTVKQMRQ 246
>XP_005272319
          Length = 430

 Score = 20.0 bits (40), Expect =   390
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF +KQMRQ
Sbjct: 238 DFTVKQMRQ 246
>XP_005272318
          Length = 441

 Score = 20.0 bits (40), Expect =   390
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DFNIKQMRQ 9
           DF +KQMRQ
Sbjct: 249 DFTVKQMRQ 257
>NP_001010939
          Length = 366

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DFNIKQMRQ 9
           DF +KQ RQ
Sbjct: 124 DFTVKQTRQ 132
>NP_003557
          Length = 1411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           +FNIKQM+
Sbjct: 151 NFNIKQMK 158
>XP_006719694
          Length = 1465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           +FNIKQM+
Sbjct: 205 NFNIKQMK 212
>XP_005269599
          Length = 253

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DFNIKQMRQ 9
          DF +KQ RQ
Sbjct: 11 DFTVKQTRQ 19
>XP_006717698
          Length = 366

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DFNIKQMRQ 9
           DF +KQ RQ
Sbjct: 124 DFTVKQTRQ 132
>NP_006311
          Length = 247

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DFNIKQMRQ 9
           DF+++Q+RQ
Sbjct: 126 DFSLEQLRQ 134
>NP_997244
          Length = 3169

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FNIKQMRQ 9
            FN+K +RQ
Sbjct: 1136 FNLKDLRQ 1143
>NP_001156372
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           DF+IK++R
Sbjct: 118 DFDIKEVR 125
>NP_001273330
          Length = 211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           DF+IK++R
Sbjct: 118 DFDIKEVR 125
>NP_660359
          Length = 229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           DF+IK++R
Sbjct: 118 DFDIKEVR 125
>NP_001033056
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NIKQMRQ 9
           N+K MRQ
Sbjct: 416 NVKHMRQ 422
>NP_000446
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FNIKQMRQ 9
           F+I+Q+RQ
Sbjct: 298 FSIRQIRQ 305
>NP_000023
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NIKQMRQ 9
           N+K MRQ
Sbjct: 453 NVKHMRQ 459
>NP_055712
          Length = 606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DFNIKQ 6
           DFN+KQ
Sbjct: 421 DFNMKQ 426
>NP_001138837
          Length = 606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DFNIKQ 6
           DFN+KQ
Sbjct: 421 DFNMKQ 426
>NP_001033057
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NIKQMRQ 9
           N+K MRQ
Sbjct: 440 NVKHMRQ 446
>NP_660149
          Length = 747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DFNIKQ 6
           DFN+KQ
Sbjct: 612 DFNMKQ 617
>NP_001263280
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DFNIKQ 6
           DFNIK+
Sbjct: 147 DFNIKE 152
>NP_001254500
          Length = 928

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FNIKQMRQ 9
           F +KQ+RQ
Sbjct: 873 FRMKQLRQ 880
>NP_001254501
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FNIKQMRQ 9
           F +KQ+RQ
Sbjct: 413 FRMKQLRQ 420
>NP_060891
          Length = 917

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FNIKQMRQ 9
           F +KQ+RQ
Sbjct: 862 FRMKQLRQ 869
>XP_005262052
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NIKQMRQ 9
           N+K MRQ
Sbjct: 477 NVKHMRQ 483
>XP_005259675
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FNIKQMRQ 9
           F+I+Q+RQ
Sbjct: 298 FSIRQIRQ 305
>XP_005259674
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FNIKQMRQ 9
           F+I+Q+RQ
Sbjct: 298 FSIRQIRQ 305
>XP_005257223
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DFNIKQ 6
           DFN+KQ
Sbjct: 241 DFNMKQ 246
>XP_006721837
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DFNIKQ 6
           DFN+KQ
Sbjct: 421 DFNMKQ 426
>XP_005265639
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DFNIKQ 6
           DFN+KQ
Sbjct: 640 DFNMKQ 645
>XP_006713478
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DFNIKQ 6
           DFN+KQ
Sbjct: 672 DFNMKQ 677
>NP_000072
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    FNIKQM 7
            FNIKQ+
Sbjct: 1952 FNIKQL 1957
>NP_001804
          Length = 2701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FNIKQMRQ 9
            FNIKQ+ +
Sbjct: 1535 FNIKQISE 1542
>NP_001138498
          Length = 2299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DFNIKQM 7
           DF++KQ+
Sbjct: 860 DFSVKQL 866
>NP_005503
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           DF+++Q+R
Sbjct: 214 DFSLQQLR 221
>NP_001122394
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           DF+++Q+R
Sbjct: 214 DFSLQQLR 221
>NP_001273663
          Length = 2580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FNIKQMRQ 9
            FNIKQ+ +
Sbjct: 1510 FNIKQISE 1517
>NP_694996
          Length = 2526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FNIKQM 7
           FNIKQ+
Sbjct: 510 FNIKQL 515
>NP_006853
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NIKQMRQ 9
          NIKQ+R+
Sbjct: 74 NIKQLRK 80
>NP_001077434
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NIKQMRQ 9
          NIKQ+R+
Sbjct: 74 NIKQLRK 80
>NP_001077433
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NIKQMRQ 9
          NIKQ+R+
Sbjct: 74 NIKQLRK 80
>NP_001077432
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NIKQMRQ 9
          NIKQ+R+
Sbjct: 74 NIKQLRK 80
>NP_001265227
          Length = 2614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FNIKQM 7
           FNIKQ+
Sbjct: 510 FNIKQL 515
>NP_079040
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NIKQMRQ 9
           NIK+M+Q
Sbjct: 992 NIKRMKQ 998
>XP_005273960
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           DF+++Q+R
Sbjct: 104 DFSLQQLR 111
>XP_005273959
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DFNIKQMR 8
           DF+++Q+R
Sbjct: 214 DFSLQQLR 221
>XP_005273954
          Length = 1676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FNIKQMRQ 9
            F IK+MR+
Sbjct: 1668 FGIKEMRR 1675
>XP_005273087
          Length = 2788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    FNIKQM 7
            FNIKQ+
Sbjct: 1952 FNIKQL 1957
>XP_006711794
          Length = 3022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    FNIKQM 7
            FNIKQ+
Sbjct: 1173 FNIKQL 1178
>XP_005273086
          Length = 3264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    FNIKQM 7
            FNIKQ+
Sbjct: 1952 FNIKQL 1957
>XP_005273084
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    FNIKQM 7
            FNIKQ+
Sbjct: 1952 FNIKQL 1957
>XP_005244911
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NIKQMRQ 9
          NIKQ+R+
Sbjct: 74 NIKQLRK 80
>XP_005244910
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NIKQMRQ 9
          NIKQ+R+
Sbjct: 74 NIKQLRK 80
>NP_068747
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  DFNIKQM 7
          D+N+KQ+
Sbjct: 79 DWNVKQL 85
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.138    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 395,514
Number of extensions: 585
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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