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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     665
XP_005262424                                                           19     665
NP_000192                                                              17    3301
NP_891548                                                              16    7355
NP_001129627                                                           16    7355
NP_001129626                                                           16    7355
NP_001278320                                                           16    7355
NP_001230361                                                           16    7355
NP_001230357                                                           16    7355
NP_056141                                                              16    7355
NP_001164108                                                           16    7355
XP_005277572                                                           16    7355
XP_005277571                                                           16    7355
XP_006711310                                                           16    7355
XP_005277570                                                           16    7355
XP_005277569                                                           16    7355
XP_006711309                                                           16    7355
XP_005277568                                                           16    7355
XP_005277567                                                           16    7355
NP_000262                                                              15    9605
NP_078966                                                              15    9605
NP_006807                                                              15    9605
NP_057490                                                              15    9605
XP_006722542                                                           15    9605
XP_005258336                                                           15    9605
XP_005258335                                                           15    9605
XP_005258334                                                           15    9605
XP_005245311                                                           15    9605

>NP_722576
          Length = 3080

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           DES QRVTA
Sbjct: 872 DESAQRVTA 880



>XP_005262424
          Length = 2875

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           DES QRVTA
Sbjct: 667 DESAQRVTA 675



>NP_000192
          Length = 532

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DESTQRVT 8
           DE TQR+T
Sbjct: 282 DEGTQRLT 289



>NP_891548
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ESTQRVT 8
           E+TQR+T
Sbjct: 239 EATQRIT 245



>NP_001129627
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ESTQRVT 8
           E+TQR+T
Sbjct: 147 EATQRIT 153



>NP_001129626
          Length = 486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ESTQRVT 8
           E+TQR+T
Sbjct: 246 EATQRIT 252



>NP_001278320
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ESTQRVT 8
           E+TQR+T
Sbjct: 246 EATQRIT 252



>NP_001230361
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ESTQRVT 8
           E+TQR+T
Sbjct: 246 EATQRIT 252



>NP_001230357
          Length = 486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ESTQRVT 8
           E+TQR+T
Sbjct: 246 EATQRIT 252



>NP_056141
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 711 EDSTQDVTA 719



>NP_001164108
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 710 EDSTQDVTA 718



>XP_005277572
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 710 EDSTQDVTA 718



>XP_005277571
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 711 EDSTQDVTA 719



>XP_006711310
          Length = 849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 711 EDSTQDVTA 719



>XP_005277570
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 558 EDSTQDVTA 566



>XP_005277569
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 558 EDSTQDVTA 566



>XP_006711309
          Length = 973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 711 EDSTQDVTA 719



>XP_005277568
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 710 EDSTQDVTA 718



>XP_005277567
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DESTQRVTA 9
           ++STQ VTA
Sbjct: 711 EDSTQDVTA 719



>NP_000262
          Length = 1278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DESTQRVTA 9
           DES   VTA
Sbjct: 228 DESVDEVTA 236



>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    STQRVT 8
            STQRVT
Sbjct: 1172 STQRVT 1177



>NP_006807
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DESTQRV 7
           DE+T+RV
Sbjct: 167 DETTERV 173



>NP_057490
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DESTQRVTA 9
          DE+T+RV +
Sbjct: 3  DEATRRVVS 11



>XP_006722542
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DESTQRVTA 9
           DES   VTA
Sbjct: 228 DESVDEVTA 236



>XP_005258336
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DESTQRVTA 9
           DES   VTA
Sbjct: 228 DESVDEVTA 236



>XP_005258335
          Length = 1295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DESTQRVTA 9
           DES   VTA
Sbjct: 228 DESVDEVTA 236



>XP_005258334
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DESTQRVTA 9
           DES   VTA
Sbjct: 228 DESVDEVTA 236



>XP_005245311
          Length = 122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DESTQRVTA 9
          DE+T+RV +
Sbjct: 3  DEATRRVVS 11



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.105    0.245 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 400,577
Number of extensions: 690
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)