Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444254                                                              20     299
NP_444253                                                              20     299
XP_005247551                                                           20     299
XP_005247550                                                           20     299
XP_006713712                                                           20     299
XP_005247549                                                           20     299
NP_057164                                                              17    3301
XP_006721603                                                           17    3301
NP_001137435                                                           17    4312
NP_076493                                                              17    4312
NP_001240317                                                           17    4312
NP_001240316                                                           17    4312
NP_006605                                                              17    4312
NP_060868                                                              17    4312
NP_066966                                                              17    4312
NP_001190179                                                           17    4312
XP_005270205                                                           17    4312
XP_005265376                                                           17    4312
XP_005265375                                                           17    4312
XP_006713004                                                           17    4312
XP_006713003                                                           17    4312
XP_006713002                                                           17    4312
XP_006713001                                                           17    4312
NP_076950                                                              17    4312
NP_000775                                                              16    5631
NP_003310                                                              16    5631
NP_597676                                                              16    5631
NP_001243779                                                           16    5631
NP_596869                                                              16    5631
NP_055524                                                              16    5631
XP_005246888                                                           16    5631
XP_006712788                                                           16    5631
XP_006712787                                                           16    5631
XP_006712786                                                           16    5631
NP_001254479                                                           16    5631
NP_597681                                                              16    5631
NP_071400                                                              16    7355
NP_055282                                                              16    7355
NP_689895                                                              16    7355
XP_005262178                                                           16    7355
XP_006724655                                                           16    7355
XP_006714195                                                           16    7355
NP_001139                                                              15    9605
NP_001274462                                                           15    9605
NP_001274463                                                           15    9605
NP_001274461                                                           15    9605
NP_006566                                                              15    9605
NP_001070663                                                           15    9605
NP_006819                                                              15    9605
NP_003794                                                              15    9605
NP_062830                                                              15    9605
NP_942089                                                              15    9605
NP_060053                                                              15    9605
NP_009070                                                              15    9605
NP_689839                                                              15    9605
XP_006720077                                                           15    9605
XP_006720076                                                           15    9605
XP_006718317                                                           15    9605
XP_006715924                                                           15    9605
XP_006715385                                                           15    9605
XP_006714257                                                           15    9605
XP_005263002                                                           15    9605
XP_005262999                                                           15    9605
XP_006714252                                                           15    9605
XP_006714251                                                           15    9605
XP_006714250                                                           15    9605
NP_085137                                                              15    9605
>NP_444254
          Length = 1845

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DEAFNEISD 9
            DEAF+EISD
Sbjct: 1613 DEAFDEISD 1621
>NP_444253
          Length = 1914

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DEAFNEISD 9
            DEAF+EISD
Sbjct: 1682 DEAFDEISD 1690
>XP_005247551
          Length = 1855

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DEAFNEISD 9
            DEAF+EISD
Sbjct: 1623 DEAFDEISD 1631
>XP_005247550
          Length = 1856

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DEAFNEISD 9
            DEAF+EISD
Sbjct: 1624 DEAFDEISD 1632
>XP_006713712
          Length = 1923

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DEAFNEISD 9
            DEAF+EISD
Sbjct: 1692 DEAFDEISD 1700
>XP_005247549
          Length = 1924

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DEAFNEISD 9
            DEAF+EISD
Sbjct: 1692 DEAFDEISD 1700
>NP_057164
          Length = 298

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DEAFNEIS 8
           DEAF E+S
Sbjct: 258 DEAFRELS 265
>XP_006721603
          Length = 289

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DEAFNEIS 8
           DEAF E+S
Sbjct: 249 DEAFRELS 256
>NP_001137435
          Length = 1248

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1165 DETFGEYSD 1173
>NP_076493
          Length = 1253

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1170 DETFGEYSD 1178
>NP_001240317
          Length = 1171

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1093 DETFGEYSD 1101
>NP_001240316
          Length = 1208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1130 DETFGEYSD 1138
>NP_006605
          Length = 1224

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1146 DETFGEYSD 1154
>NP_060868
          Length = 1091

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DEAFNEISD 9
           +EAFN +SD
Sbjct: 343 NEAFNILSD 351
>NP_066966
          Length = 532

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  EAFNEISD 9
          E+FN+I+D
Sbjct: 84 ESFNQIAD 91
>NP_001190179
          Length = 529

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  EAFNEISD 9
          E+FN+I+D
Sbjct: 81 ESFNQIAD 88
>XP_005270205
          Length = 672

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DEAFNEISD 9
          +E FN +SD
Sbjct: 10 EEGFNRLSD 18
>XP_005265376
          Length = 877

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DEAFNEISD 9
           +EAFN +SD
Sbjct: 343 NEAFNILSD 351
>XP_005265375
          Length = 1085

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DEAFNEISD 9
           +EAFN +SD
Sbjct: 343 NEAFNILSD 351
>XP_006713004
          Length = 1171

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1093 DETFGEYSD 1101
>XP_006713003
          Length = 1224

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1146 DETFGEYSD 1154
>XP_006713002
          Length = 1224

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1146 DETFGEYSD 1154
>XP_006713001
          Length = 1224

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    DEAFNEISD 9
            DE F E SD
Sbjct: 1146 DETFGEYSD 1154
>NP_076950
          Length = 737

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DEAFNEISD 9
          +E FN +SD
Sbjct: 75 EEGFNRLSD 83
>NP_000775
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EAFNEISD 9
           +AFNE+ D
Sbjct: 176 DAFNEVID 183
>NP_003310
          Length = 26926

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 24971 EEAFKEIS 24978
>NP_597676
          Length = 27051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 25096 EEAFKEIS 25103
>NP_001243779
          Length = 34350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 32395 EEAFKEIS 32402
>NP_596869
          Length = 33423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 31468 EEAFKEIS 31475
>NP_055524
          Length = 3546

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EAFNEISD 9
          E  NEISD
Sbjct: 10 EVLNEISD 17

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E F E+SD
Sbjct: 2131 EGFKEVSD 2138
>XP_005246888
          Length = 22663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 20708 EEAFKEIS 20715
>XP_006712788
          Length = 24022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 22067 EEAFKEIS 22074
>XP_006712787
          Length = 33978

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 32023 EEAFKEIS 32030
>XP_006712786
          Length = 35484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 33529 EEAFKEIS 33536
>NP_001254479
          Length = 35991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 34036 EEAFKEIS 34043
>NP_597681
          Length = 27118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     DEAFNEIS 8
             +EAF EIS
Sbjct: 25163 EEAFKEIS 25170
>NP_071400
          Length = 693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DEAFNEISD 9
           ++ F+EISD
Sbjct: 434 EDIFSEISD 442
>NP_055282
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  DEAFNEI 7
          DE++NE+
Sbjct: 34 DESYNEV 40
>NP_689895
          Length = 188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DEAFNEIS 8
          DE+F E+S
Sbjct: 21 DESFRELS 28
>XP_005262178
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  DEAFNEI 7
          DE++NE+
Sbjct: 34 DESYNEV 40
>XP_006724655
          Length = 694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DEAFNEISD 9
           ++ F+EISD
Sbjct: 434 EDIFSEISD 442
>XP_006714195
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DEAFNEIS 8
          DE+F E+S
Sbjct: 21 DESFRELS 28
>NP_001139
          Length = 3957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E F EISD
Sbjct: 3476 EFFEEISD 3483
>NP_001274462
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DEAFNEIS 8
           D+AFN+ S
Sbjct: 467 DKAFNKFS 474
>NP_001274463
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DEAFNEIS 8
           D+AFN+ S
Sbjct: 467 DKAFNKFS 474
>NP_001274461
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DEAFNEIS 8
           D+AFN+ S
Sbjct: 511 DKAFNKFS 518
>NP_006566
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DEAFNEISD 9
           DE   EISD
Sbjct: 798 DEVTQEISD 806
>NP_001070663
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EAFNEISD 9
           +AF++ISD
Sbjct: 145 KAFSQISD 152
>NP_006819
          Length = 2202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E FNE+ D
Sbjct: 996  ETFNELFD 1003
>NP_003794
          Length = 1685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DEAFNEI 7
            DEAF E+
Sbjct: 1445 DEAFKEL 1451
>NP_062830
          Length = 1589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DEAFNEI 7
            DEAF E+
Sbjct: 1349 DEAFKEL 1355
>NP_942089
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DEAFNEISD 9
           DE   EISD
Sbjct: 798 DEVTQEISD 806
>NP_060053
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DEAFNEI 7
           DEAF E+
Sbjct: 216 DEAFEEL 222
>NP_009070
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DEAFNEIS 8
           D+AFN+ S
Sbjct: 474 DKAFNKFS 481
>NP_689839
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DEAFNEIS 8
           D+AFN+ S
Sbjct: 543 DKAFNKFS 550
>XP_006720077
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DEAFNEISD 9
           DE   EISD
Sbjct: 441 DEVTQEISD 449
>XP_006720076
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DEAFNEISD 9
           DE   EISD
Sbjct: 798 DEVTQEISD 806
>XP_006718317
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DEAFNEI 7
           DEAF E+
Sbjct: 216 DEAFEEL 222
>XP_006715924
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DEAFNEIS 8
           D+AFN+ S
Sbjct: 515 DKAFNKFS 522
>XP_006715385
          Length = 1866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   EAFNEISD 9
           E FNE+ D
Sbjct: 660 ETFNELFD 667
>XP_006714257
          Length = 4145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E F EISD
Sbjct: 3485 EFFEEISD 3492
>XP_005263002
          Length = 4072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E F EISD
Sbjct: 3443 EFFEEISD 3450
>XP_005262999
          Length = 4147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E F EISD
Sbjct: 3487 EFFEEISD 3494
>XP_006714252
          Length = 4153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E F EISD
Sbjct: 3493 EFFEEISD 3500
>XP_006714251
          Length = 4165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E F EISD
Sbjct: 3505 EFFEEISD 3512
>XP_006714250
          Length = 4190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    EAFNEISD 9
            E F EISD
Sbjct: 3530 EFFEEISD 3537
>NP_085137
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EAFNEISD 9
           +AF++ISD
Sbjct: 145 KAFSQISD 152
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.127    0.329 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 510,916
Number of extensions: 1202
Number of successful extensions: 68
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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