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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     665
XP_006716142                                                           19     665
XP_005250088                                                           19     665
XP_006716141                                                           19     665
XP_005250085                                                           19     665
XP_006716140                                                           19     665
XP_005250084                                                           19     665
XP_005250083                                                           19     665
XP_005250082                                                           19     665
NP_003473                                                              18    1482
XP_006719679                                                           18    1482
XP_005269219                                                           18    1482
XP_006719678                                                           18    1482
XP_006719677                                                           18    1482
NP_001159751                                                           18    1935
NP_055686                                                              18    1935
NP_001120932                                                           18    1935
NP_000287                                                              16    5631
NP_001009944                                                           16    5631
NP_001230925                                                           16    5631
NP_001027                                                              16    5631
XP_005276550                                                           16    5631
XP_005255427                                                           16    5631
XP_006720956                                                           16    5631
XP_006720955                                                           16    5631
XP_006720954                                                           16    5631
XP_006720953                                                           16    5631
XP_006720952                                                           16    5631
NP_001107859                                                           16    7355
NP_872412                                                              16    7355
XP_006714269                                                           16    7355
NP_689497                                                              16    7355

>NP_733751
          Length = 4911

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4530 DEVRQIASI 4538



>XP_006716142
          Length = 4927

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4546 DEVRQIASI 4554



>XP_005250088
          Length = 4928

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4547 DEVRQIASI 4555



>XP_006716141
          Length = 4959

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4578 DEVRQIASI 4586



>XP_005250085
          Length = 4979

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4602 DEVRQIASI 4610



>XP_006716140
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4601 DEVRQIASI 4609



>XP_005250084
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4601 DEVRQIASI 4609



>XP_005250083
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4601 DEVRQIASI 4609



>XP_005250082
          Length = 4983

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+VRQIASI
Sbjct: 4602 DEVRQIASI 4610



>NP_003473
          Length = 5537

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+V+QIASI
Sbjct: 5160 DEVKQIASI 5168



>XP_006719679
          Length = 5536

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+V+QIASI
Sbjct: 5159 DEVKQIASI 5167



>XP_005269219
          Length = 5537

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+V+QIASI
Sbjct: 5160 DEVKQIASI 5168



>XP_006719678
          Length = 5539

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+V+QIASI
Sbjct: 5162 DEVKQIASI 5170



>XP_006719677
          Length = 5540

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    DDVRQIASI 9
            D+V+QIASI
Sbjct: 5163 DEVKQIASI 5171



>NP_001159751
          Length = 1201

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDVRQIASI 9
           DD+RQI S+
Sbjct: 117 DDIRQIQSL 125



>NP_055686
          Length = 1198

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDVRQIASI 9
           DD+RQI S+
Sbjct: 117 DDIRQIQSL 125



>NP_001120932
          Length = 1202

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDVRQIASI 9
           DD+RQI S+
Sbjct: 117 DDIRQIQSL 125



>NP_000287
          Length = 4302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    DDVRQIAS 8
            DD++QIA+
Sbjct: 2659 DDIQQIAA 2666



>NP_001009944
          Length = 4303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    DDVRQIAS 8
            DD++QIA+
Sbjct: 2659 DDIQQIAA 2666



>NP_001230925
          Length = 4865

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    DDVRQI 6
            DDVRQI
Sbjct: 1741 DDVRQI 1746



>NP_001027
          Length = 4870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    DDVRQI 6
            DDVRQI
Sbjct: 1741 DDVRQI 1746



>XP_005276550
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DDVRQIAS 8
           DD++QIA+
Sbjct: 164 DDIQQIAA 171



>XP_005255427
          Length = 3288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    DDVRQIAS 8
            DD++QIA+
Sbjct: 1644 DDIQQIAA 1651



>XP_006720956
          Length = 3895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    DDVRQIAS 8
            DD++QIA+
Sbjct: 2251 DDIQQIAA 2258



>XP_006720955
          Length = 4279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    DDVRQIAS 8
            DD++QIA+
Sbjct: 2635 DDIQQIAA 2642



>XP_006720954
          Length = 4334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    DDVRQIAS 8
            DD++QIA+
Sbjct: 2696 DDIQQIAA 2703



>XP_006720953
          Length = 4339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    DDVRQIAS 8
            DD++QIA+
Sbjct: 2696 DDIQQIAA 2703



>XP_006720952
          Length = 4340

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    DDVRQIAS 8
            DD++QIA+
Sbjct: 2696 DDIQQIAA 2703



>NP_001107859
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DDVRQI 6
           DD+RQI
Sbjct: 286 DDIRQI 291



>NP_872412
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DDVRQI 6
           DD+RQI
Sbjct: 289 DDIRQI 294



>XP_006714269
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DDVRQI 6
           DD+RQI
Sbjct: 255 DDIRQI 260



>NP_689497
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDVRQIAS 8
           DD++Q+A+
Sbjct: 223 DDIKQLAA 230



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.137    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 340,588
Number of extensions: 426
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)