Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     509
NP_001075109                                                           20     509
NP_001269889                                                           17    3301
NP_001269888                                                           17    3301
NP_060707                                                              17    3301
NP_001191230                                                           17    4312
NP_001191232                                                           17    4312
NP_001129488                                                           17    4312
NP_001191231                                                           17    4312
NP_001129603                                                           17    4312
NP_958817                                                              17    4312
NP_001129602                                                           17    4312
NP_001129601                                                           17    4312
NP_958816                                                              17    4312
NP_000475                                                              17    4312
NP_001177645                                                           16    7355
NP_001275668                                                           16    7355
NP_004399                                                              16    7355
NP_001275667                                                           16    7355
NP_001005336                                                           16    7355
NP_001275666                                                           16    7355
NP_004936                                                              16    7355
NP_001005361                                                           16    7355
NP_001005360                                                           16    7355
NP_001005362                                                           16    7355
NP_056384                                                              16    7355
NP_001129599                                                           16    7355
NP_001265181                                                           16    7355
NP_001253989                                                           16    7355
NP_775267                                                              16    7355
NP_775268                                                              16    7355
NP_001253990                                                           16    7355
NP_001253988                                                           16    7355
NP_055563                                                              16    7355
NP_001018100                                                           16    7355
NP_001272829                                                           16    7355
NP_001018112                                                           16    7355
NP_937886                                                              16    7355
NP_775266                                                              16    7355
NP_004094                                                              16    7355
NP_056347                                                              16    7355
XP_006717057                                                           16    7355
XP_006717056                                                           16    7355
XP_005251826                                                           16    7355
XP_005251825                                                           16    7355
XP_005251821                                                           16    7355
XP_005251820                                                           16    7355
XP_006717055                                                           16    7355
XP_005273505                                                           16    7355
XP_005273504                                                           16    7355
XP_006711331                                                           16    7355
XP_005245141                                                           16    7355
XP_005245139                                                           16    7355
XP_005245138                                                           16    7355
XP_005245137                                                           16    7355
XP_005245136                                                           16    7355
NP_078984                                                              16    7355
NP_689596                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVLANRLL 9
            D+VLANRLL
Sbjct: 2208 DEVLANRLL 2216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    DDVLANR 7
            DD++ NR
Sbjct: 3180 DDIITNR 3186
>NP_001075109
          Length = 4097

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DDVLANRLL 9
            D+VLANRLL
Sbjct: 2208 DEVLANRLL 2216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    DDVLANR 7
            DD++ NR
Sbjct: 3180 DDIITNR 3186
>NP_001269889
          Length = 1135

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDVLANRLL 9
           +D+L NRLL
Sbjct: 982 EDMLGNRLL 990
>NP_001269888
          Length = 1135

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDVLANRLL 9
           +D+L NRLL
Sbjct: 982 EDMLGNRLL 990
>NP_060707
          Length = 1150

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DDVLANRLL 9
            +D+L NRLL
Sbjct: 997  EDMLGNRLL 1005
>NP_001191230
          Length = 752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 574 DDVLANMI 581
>NP_001191232
          Length = 677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 499 DDVLANMI 506
>NP_001129488
          Length = 746

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 550 DDVLANMI 557
>NP_001191231
          Length = 733

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 555 DDVLANMI 562
>NP_001129603
          Length = 660

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 464 DDVLANMI 471
>NP_958817
          Length = 695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 499 DDVLANMI 506
>NP_001129602
          Length = 714

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 518 DDVLANMI 525
>NP_001129601
          Length = 639

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 443 DDVLANMI 450
>NP_958816
          Length = 751

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 555 DDVLANMI 562
>NP_000475
          Length = 770

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDVLAN +
Sbjct: 574 DDVLANMI 581
>NP_001177645
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001275668
          Length = 864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_004399
          Length = 864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001275667
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001005336
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001275666
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_004936
          Length = 866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001005361
          Length = 870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001005360
          Length = 870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001005362
          Length = 866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_056384
          Length = 863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001129599
          Length = 859

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001265181
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_001253989
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDV+ NR+
Sbjct: 187 DDVMENRV 194
>NP_775267
          Length = 967

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DDVLANRLL 9
           +DV+ NR+L
Sbjct: 423 EDVVLNRIL 431
>NP_775268
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DDVLANRLL 9
           +DV+ NR+L
Sbjct: 423 EDVVLNRIL 431
>NP_001253990
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDV+ NR+
Sbjct: 192 DDVMENRV 199
>NP_001253988
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDV+ NR+
Sbjct: 200 DDVMENRV 207
>NP_055563
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DDVLANRL 8
           DDV+ NR+
Sbjct: 212 DDVMENRV 219
>NP_001018100
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDVLANRLL 9
           DD+ A RLL
Sbjct: 468 DDITAARLL 476
>NP_001272829
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDVLANRLL 9
           DD+ A RLL
Sbjct: 683 DDITAARLL 691
>NP_001018112
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDVLANRLL 9
           DD+ A RLL
Sbjct: 129 DDITAARLL 137
>NP_937886
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDVLANRLL 9
           DDVL  R+L
Sbjct: 225 DDVLCARML 233
>NP_775266
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DDVLANRLL 9
           +DV+ NR+L
Sbjct: 423 EDVVLNRIL 431
>NP_004094
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DDVLANRLL 9
           +DV+ NR+L
Sbjct: 423 EDVVLNRIL 431
>NP_056347
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDVLANRLL 9
           DD+ A RLL
Sbjct: 286 DDITAARLL 294
>XP_006717057
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_006717056
          Length = 498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005251826
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005251825
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005251821
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005251820
          Length = 868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_006717055
          Length = 868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005273505
          Length = 997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DDVLANRLL 9
           +DV+ NR+L
Sbjct: 423 EDVVLNRIL 431
>XP_005273504
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DDVLANRLL 9
           +DV+ NR+L
Sbjct: 423 EDVVLNRIL 431
>XP_006711331
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005245141
          Length = 608

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005245139
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 108 DVLENKLL 115
>XP_005245138
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005245137
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>XP_005245136
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL N+LL
Sbjct: 218 DVLENKLL 225
>NP_078984
          Length = 274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDVLANRLL 9
           DDVL  R+L
Sbjct: 225 DDVLCARML 233
>NP_689596
          Length = 885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLANRLL 9
           DVL +RLL
Sbjct: 708 DVLVHRLL 715
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.147    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 387,113
Number of extensions: 455
Number of successful extensions: 60
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package