Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              19     665
NP_001120972                                                           19     665
XP_006716052                                                           19     665
XP_006716051                                                           19     665
NP_065962                                                              18    1935
NP_115618                                                              18    1935
XP_005250744                                                           18    1935
XP_005250743                                                           18    1935
XP_006716234                                                           18    1935
XP_006713726                                                           18    1935
NP_001099013                                                           18    1935
NP_861440                                                              18    1935
NP_065861                                                              17    4312
XP_005267973                                                           17    4312
XP_006714228                                                           17    4312
XP_006714227                                                           17    4312
XP_006714226                                                           17    4312
XP_006714225                                                           17    4312
XP_006714224                                                           17    4312
XP_006714223                                                           17    4312
XP_006714222                                                           17    4312
XP_006714221                                                           17    4312
XP_006714220                                                           17    4312
NP_001123539                                                           17    4312
NP_056086                                                              17    4312
NP_570118                                                              16    5631
NP_570116                                                              16    5631
NP_001269828                                                           16    5631
NP_001269829                                                           16    5631
NP_001269830                                                           16    5631
NP_001093867                                                           16    5631
NP_008954                                                              16    5631
NP_060009                                                              16    5631
XP_005259315                                                           16    5631
XP_005259314                                                           16    5631
XP_006721125                                                           16    5631
XP_006712269                                                           16    5631
XP_006712268                                                           16    5631
XP_005246303                                                           16    5631
NP_077297                                                              16    5631
NP_000050                                                              16    7355
XP_006714032                                                           16    7355
NP_954868                                                              15    9605
NP_954869                                                              15    9605
NP_001277153                                                           15    9605
NP_954870                                                              15    9605
NP_056516                                                              15    9605
NP_001120869                                                           15    9605
NP_954863                                                              15    9605
NP_002034                                                              15    9605
NP_060829                                                              15    9605
NP_001120870                                                           15    9605
NP_570141                                                              15    9605
>NP_000236
          Length = 1390

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DDILF VFA
Sbjct: 339 DDILFGVFA 347
>NP_001120972
          Length = 1408

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DDILF VFA
Sbjct: 339 DDILFGVFA 347
>XP_006716052
          Length = 1409

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DDILF VFA
Sbjct: 358 DDILFGVFA 366
>XP_006716051
          Length = 1427

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DDILF VFA
Sbjct: 358 DDILFGVFA 366
>NP_065962
          Length = 1894

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DD+LF VF+
Sbjct: 332 DDLLFTVFS 340
>NP_115618
          Length = 1896

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           +D+LF VFA
Sbjct: 334 EDVLFTVFA 342
>XP_005250744
          Length = 522

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DD+LF VF+
Sbjct: 332 DDLLFTVFS 340
>XP_005250743
          Length = 1894

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DD+LF VF+
Sbjct: 332 DDLLFTVFS 340
>XP_006716234
          Length = 1894

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DD+LF VF+
Sbjct: 332 DDLLFTVFS 340
>XP_006713726
          Length = 1910

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           +D+LF VFA
Sbjct: 352 EDVLFTVFA 360
>NP_001099013
          Length = 492

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DD+LF VF+
Sbjct: 332 DDLLFTVFS 340
>NP_861440
          Length = 522

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DDILFRVFA 9
           DD+LF VF+
Sbjct: 332 DDLLFTVFS 340
>NP_065861
          Length = 509

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DILFRVFA 9
           D+LF VFA
Sbjct: 300 DVLFDVFA 307
>XP_005267973
          Length = 537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DILFRVFA 9
           D+LF VFA
Sbjct: 328 DVLFDVFA 335
>XP_006714228
          Length = 623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 345 DDLIFRV 351
>XP_006714227
          Length = 623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 345 DDLIFRV 351
>XP_006714226
          Length = 629

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 351 DDLIFRV 357
>XP_006714225
          Length = 748

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 470 DDLIFRV 476
>XP_006714224
          Length = 748

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 470 DDLIFRV 476
>XP_006714223
          Length = 748

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 470 DDLIFRV 476
>XP_006714222
          Length = 766

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 488 DDLIFRV 494
>XP_006714221
          Length = 774

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 496 DDLIFRV 502
>XP_006714220
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 497 DDLIFRV 503
>NP_001123539
          Length = 744

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 470 DDLIFRV 476
>NP_056086
          Length = 771

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           DD++FRV
Sbjct: 497 DDLIFRV 503
>NP_570118
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           +D+LFRV
Sbjct: 179 EDVLFRV 185
>NP_570116
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DDILFRV 7
           +D+LFRV
Sbjct: 179 EDVLFRV 185
>NP_001269828
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDILFRVF 8
           D++LF+V+
Sbjct: 515 DEVLFKVY 522
>NP_001269829
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDILFRVF 8
           D++LF+V+
Sbjct: 497 DEVLFKVY 504
>NP_001269830
          Length = 791

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDILFRVF 8
           D++LF+V+
Sbjct: 448 DEVLFKVY 455
>NP_001093867
          Length = 867

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDILFRVF 8
           D++LF+V+
Sbjct: 524 DEVLFKVY 531
>NP_008954
          Length = 1011

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDILFRVF 8
           D++LF+V+
Sbjct: 668 DEVLFKVY 675
>NP_060009
          Length = 4116

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DDILFRVFA 9
            DDIL ++F+
Sbjct: 2217 DDILTKIFS 2225
>XP_005259315
          Length = 451

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDILFRVFA 9
           DDIL R F+
Sbjct: 365 DDILARAFS 373
>XP_005259314
          Length = 473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDILFRVFA 9
           DDIL R F+
Sbjct: 387 DDILARAFS 395
>XP_006721125
          Length = 4070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DDILFRVFA 9
            DDIL ++F+
Sbjct: 2171 DDILTKIFS 2179
>XP_006712269
          Length = 838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDILFRVF 8
           D++LF+V+
Sbjct: 495 DEVLFKVY 502
>XP_006712268
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDILFRVF 8
           D++LF+V+
Sbjct: 497 DEVLFKVY 504
>XP_005246303
          Length = 993

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DDILFRVF 8
           D++LF+V+
Sbjct: 650 DEVLFKVY 657
>NP_077297
          Length = 480

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDILFRVFA 9
           DDIL R F+
Sbjct: 394 DDILARAFS 402
>NP_000050
          Length = 3418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    DDILFRVF 8
            D+ILF+++
Sbjct: 3042 DEILFQIY 3049
>XP_006714032
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ILFRVFA 9
           ILF+VFA
Sbjct: 412 ILFQVFA 418
>NP_954868
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DILFRVF 8
           D+L RVF
Sbjct: 122 DVLLRVF 128
>NP_954869
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DILFRVF 8
           D+L RVF
Sbjct: 102 DVLLRVF 108
>NP_001277153
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 DILFRVF 8
         D+L RVF
Sbjct: 2 DVLLRVF 8
>NP_954870
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DILFRVF 8
           D+L RVF
Sbjct: 140 DVLLRVF 146
>NP_056516
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  DDILFRV 7
          DDI FRV
Sbjct: 39 DDIPFRV 45
>NP_001120869
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  DDILFRV 7
          DDI FRV
Sbjct: 39 DDIPFRV 45
>NP_954863
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DILFRVF 8
           D+L RVF
Sbjct: 122 DVLLRVF 128
>NP_002034
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DDILFRVF 8
           D+I+ RVF
Sbjct: 154 DNIMLRVF 161
>NP_060829
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  DILFRV 7
          DILFR+
Sbjct: 8  DILFRI 13
>NP_001120870
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  DDILFRV 7
          DDI FRV
Sbjct: 39 DDIPFRV 45
>NP_570141
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  DILFRVF 8
          D+L RVF
Sbjct: 85 DVLLRVF 91
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.351    0.166    0.497 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 420,054
Number of extensions: 853
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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