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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1135
NP_671714                                                              18    1135
XP_006715890                                                           18    1135
XP_005250160                                                           18    1135
XP_005250159                                                           18    1135
NP_057526                                                              16    5631
NP_001185470                                                           16    5631
NP_001035548                                                           16    5631
NP_001123999                                                           16    5631
NP_001035529                                                           16    5631
NP_055948                                                              16    5631
NP_001124000                                                           16    5631
NP_001238900                                                           16    5631
NP_003962                                                              16    5631
XP_005257831                                                           16    5631
XP_006722226                                                           16    5631
XP_005257830                                                           16    5631
XP_005257829                                                           16    5631
XP_005257828                                                           16    5631
XP_005257827                                                           16    5631
XP_005257826                                                           16    5631
XP_005257825                                                           16    5631
XP_005257824                                                           16    5631
XP_006720932                                                           16    5631
XP_005255247                                                           16    5631
XP_006720931                                                           16    5631
XP_005255245                                                           16    5631
XP_005255244                                                           16    5631
XP_005272073                                                           16    5631
XP_005272072                                                           16    5631
NP_002197                                                              15    9605
NP_001138468                                                           15    9605
NP_001138469                                                           15    9605
NP_001137310                                                           15    9605
NP_808218                                                              15    9605
NP_001271439                                                           15    9605
NP_001271438                                                           15    9605
XP_006721567                                                           15    9605
XP_005268907                                                           15    9605
XP_005268906                                                           15    9605
XP_005268905                                                           15    9605
XP_005268904                                                           15    9605
XP_005268903                                                           15    9605
XP_005268902                                                           15    9605
XP_005268901                                                           15    9605
XP_005268899                                                           15    9605
XP_005268898                                                           15    9605
XP_005268897                                                           15    9605
XP_005268896                                                           15    9605

>NP_005742
          Length = 3907

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DATLALFAR 9
            DATLAL AR
Sbjct: 3734 DATLALLAR 3742



>NP_671714
          Length = 3899

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DATLALFAR 9
            DATLAL AR
Sbjct: 3726 DATLALLAR 3734



>XP_006715890
          Length = 3860

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DATLALFAR 9
            DATLAL AR
Sbjct: 3687 DATLALLAR 3695



>XP_005250160
          Length = 3939

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DATLALFAR 9
            DATLAL AR
Sbjct: 3766 DATLALLAR 3774



>XP_005250159
          Length = 3952

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DATLALFAR 9
            DATLAL AR
Sbjct: 3779 DATLALLAR 3787



>NP_057526
          Length = 948

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DATLALFA 8
           D TLA+FA
Sbjct: 766 DVTLAVFA 773



>NP_001185470
          Length = 941

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DATLALFA 8
           D TLA+FA
Sbjct: 766 DVTLAVFA 773



>NP_001035548
          Length = 941

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DATLALFA 8
           D TLA+FA
Sbjct: 766 DVTLAVFA 773



>NP_001123999
          Length = 1311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1009 DGTLAIFHR 1017



>NP_001035529
          Length = 1330

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1012 DGTLAIFHR 1020



>NP_055948
          Length = 1336

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1018 DGTLAIFHR 1026



>NP_001124000
          Length = 1321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1019 DGTLAIFHR 1027



>NP_001238900
          Length = 1177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DATLALFAR 9
           D TLA+F R
Sbjct: 862 DGTLAIFHR 870



>NP_003962
          Length = 1307

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1005 DGTLAIFHR 1013



>XP_005257831
          Length = 1164

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DATLALFAR 9
           D TLA+F R
Sbjct: 862 DGTLAIFHR 870



>XP_006722226
          Length = 1173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DATLALFAR 9
           D TLA+F R
Sbjct: 858 DGTLAIFHR 866



>XP_005257830
          Length = 1181

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DATLALFAR 9
           D TLA+F R
Sbjct: 866 DGTLAIFHR 874



>XP_005257829
          Length = 1195

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DATLALFAR 9
           D TLA+F R
Sbjct: 880 DGTLAIFHR 888



>XP_005257828
          Length = 1320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1005 DGTLAIFHR 1013



>XP_005257827
          Length = 1324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1009 DGTLAIFHR 1017



>XP_005257826
          Length = 1325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1023 DGTLAIFHR 1031



>XP_005257825
          Length = 1334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1019 DGTLAIFHR 1027



>XP_005257824
          Length = 1338

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1023 DGTLAIFHR 1031



>XP_006720932
          Length = 1083

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DATLALFAR 9
           D TLA+F R
Sbjct: 765 DGTLAIFHR 773



>XP_005255247
          Length = 1322

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1004 DGTLAIFHR 1012



>XP_006720931
          Length = 1328

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1010 DGTLAIFHR 1018



>XP_005255245
          Length = 1331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1013 DGTLAIFHR 1021



>XP_005255244
          Length = 1337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DATLALFAR 9
            D TLA+F R
Sbjct: 1019 DGTLAIFHR 1027



>XP_005272073
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DATLALFA 8
           D TLA+FA
Sbjct: 766 DVTLAVFA 773



>XP_005272072
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DATLALFA 8
           D TLA+FA
Sbjct: 766 DVTLAVFA 773



>NP_002197
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 671 DGTTALFA 678



>NP_001138468
          Length = 1141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 675 DGTTALFA 682



>NP_001138469
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 578 DGTTALFA 585



>NP_001137310
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DATLALF 7
           DAT+A+F
Sbjct: 356 DATVAIF 362



>NP_808218
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DATLALF 7
           DAT+A+F
Sbjct: 356 DATVAIF 362



>NP_001271439
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DATLALF 7
           DAT+A+F
Sbjct: 313 DATVAIF 319



>NP_001271438
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DATLALF 7
           DAT+A+F
Sbjct: 339 DATVAIF 345



>XP_006721567
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DATLALF 7
           DAT+A+F
Sbjct: 319 DATVAIF 325



>XP_005268907
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 513 DGTTALFA 520



>XP_005268906
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 557 DGTTALFA 564



>XP_005268905
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 557 DGTTALFA 564



>XP_005268904
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 557 DGTTALFA 564



>XP_005268903
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 558 DGTTALFA 565



>XP_005268902
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 558 DGTTALFA 565



>XP_005268901
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 602 DGTTALFA 609



>XP_005268899
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 665 DGTTALFA 672



>XP_005268898
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 715 DGTTALFA 722



>XP_005268897
          Length = 1175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 709 DGTTALFA 716



>XP_005268896
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DATLALFA 8
           D T ALFA
Sbjct: 715 DGTTALFA 722



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.138    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 272,202
Number of extensions: 311
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)