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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     390
NP_001075109                                                           20     390
NP_001002858                                                           17    3301
NP_001129487                                                           17    3301
NP_004030                                                              17    3301
NP_001002857                                                           17    3301
NP_006166                                                              17    4312
NP_001248392                                                           17    4312
NP_932326                                                              17    4312
XP_005269924                                                           17    4312
XP_005269922                                                           17    4312
XP_006717933                                                           17    4312
XP_005269921                                                           17    4312
NP_005547                                                              16    5631
NP_951059                                                              15    9605
NP_060119                                                              15    9605
NP_951058                                                              15    9605
NP_001127878                                                           15    9605
NP_001127877                                                           15    9605
NP_612147                                                              15    9605
NP_005773                                                              15    9605
NP_064569                                                              15    9605
XP_006717971                                                           15    9605
XP_005269990                                                           15    9605
XP_005250215                                                           15    9605
XP_005250214                                                           15    9605
XP_005250213                                                           15    9605
XP_005263972                                                           15    9605
XP_005263971                                                           15    9605

>NP_008835
          Length = 4128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DAKMDAMNI 9
            DAKMD MNI
Sbjct: 3170 DAKMDPMNI 3178



>NP_001075109
          Length = 4097

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DAKMDAMNI 9
            DAKMD MNI
Sbjct: 3170 DAKMDPMNI 3178



>NP_001002858
          Length = 357

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DAKMDAMNI 9
          DA+ DA+NI
Sbjct: 52 DAERDALNI 60



>NP_001129487
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DAKMDAMNI 9
          DA+ DA+NI
Sbjct: 34 DAERDALNI 42



>NP_004030
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DAKMDAMNI 9
          DA+ DA+NI
Sbjct: 34 DAERDALNI 42



>NP_001002857
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DAKMDAMNI 9
          DA+ DA+NI
Sbjct: 34 DAERDALNI 42



>NP_006166
          Length = 1695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AKMDAMNI 9
           AK++AMNI
Sbjct: 982 AKLNAMNI 989



>NP_001248392
          Length = 1731

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    AKMDAMNI 9
            AK++AMNI
Sbjct: 1017 AKLNAMNI 1024



>NP_932326
          Length = 1730

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    AKMDAMNI 9
            AK++AMNI
Sbjct: 1017 AKLNAMNI 1024



>XP_005269924
          Length = 1627

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    AKMDAMNI 9
            AK++AMNI
Sbjct: 1017 AKLNAMNI 1024



>XP_005269922
          Length = 1695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AKMDAMNI 9
           AK++AMNI
Sbjct: 981 AKLNAMNI 988



>XP_006717933
          Length = 1696

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AKMDAMNI 9
           AK++AMNI
Sbjct: 982 AKLNAMNI 989



>XP_005269921
          Length = 1696

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AKMDAMNI 9
           AK++AMNI
Sbjct: 982 AKLNAMNI 989



>NP_005547
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DAKMDAMN 8
           +AK+DA+N
Sbjct: 212 EAKVDALN 219



>NP_951059
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DAKMDAM 7
           D K+DAM
Sbjct: 528 DTKLDAM 534



>NP_060119
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DAKMDAM 7
           D K+DAM
Sbjct: 528 DTKLDAM 534



>NP_951058
          Length = 853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DAKMDAM 7
           D K+DAM
Sbjct: 528 DTKLDAM 534



>NP_001127878
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   DAKMDAMNI 9
           D K D +N+
Sbjct: 348 DGKQDTLNV 356



>NP_001127877
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   DAKMDAMNI 9
           D K D +N+
Sbjct: 397 DGKQDTLNV 405



>NP_612147
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   DAKMDAMNI 9
           D K D +N+
Sbjct: 414 DGKQDTLNV 422



>NP_005773
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DAKMDAMN 8
           DA++DA N
Sbjct: 251 DAQLDAYN 258



>NP_064569
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DAKMDAM 7
           D K+DAM
Sbjct: 455 DTKLDAM 461



>XP_006717971
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DAKMDAM 7
           D K+DAM
Sbjct: 528 DTKLDAM 534



>XP_005269990
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DAKMDAM 7
           D K+DAM
Sbjct: 528 DTKLDAM 534



>XP_005250215
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   DAKMDAMNI 9
           D K D +N+
Sbjct: 277 DGKQDTLNV 285



>XP_005250214
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   DAKMDAMNI 9
           D K D +N+
Sbjct: 283 DGKQDTLNV 291



>XP_005250213
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   DAKMDAMNI 9
           D K D +N+
Sbjct: 395 DGKQDTLNV 403



>XP_005263972
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DAKMDAM 7
           D K+DAM
Sbjct: 455 DTKLDAM 461



>XP_005263971
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DAKMDAM 7
           D K+DAM
Sbjct: 455 DTKLDAM 461



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.124    0.324 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 333,819
Number of extensions: 448
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)