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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              22     134
XP_005273257                                                           22     134
NP_001231891                                                           16    5631
XP_006719261                                                           16    5631
NP_006567                                                              16    5631
NP_056370                                                              16    7355
NP_001026794                                                           16    7355
NP_004123                                                              16    7355
NP_001171131                                                           16    7355
NP_001019246                                                           16    7355
NP_078953                                                              16    7355
XP_005249051                                                           16    7355
NP_005914                                                              15    9605
NP_065928                                                              15    9605
XP_005256527                                                           15    9605
XP_005267049                                                           15    9605
XP_005267047                                                           15    9605
XP_006715545                                                           15    9605
XP_005267048                                                           15    9605

>NP_064450
          Length = 1722

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CYIKITTRQ 9
           CYIK TTRQ
Sbjct: 417 CYIKTTTRQ 425



>XP_005273257
          Length = 1726

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CYIKITTRQ 9
           CYIK TTRQ
Sbjct: 417 CYIKTTTRQ 425



>NP_001231891
          Length = 213

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CYIKITTRQ 9
          C +KI TR+
Sbjct: 17 CLVKIQTRR 25



>XP_006719261
          Length = 819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CYIKITTRQ 9
          CY+ ++TR+
Sbjct: 42 CYVILSTRR 50



>NP_006567
          Length = 819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CYIKITTRQ 9
          CY+ ++TR+
Sbjct: 42 CYVILSTRR 50



>NP_056370
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CYIKITTRQ 9
           CY K  T+Q
Sbjct: 217 CYKKFVTQQ 225



>NP_001026794
          Length = 1061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CYIKITTRQ 9
           CY K  T+Q
Sbjct: 217 CYKKFVTQQ 225



>NP_004123
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CYIKIT 6
           C+IK+T
Sbjct: 257 CFIKVT 262



>NP_001171131
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CYIKIT 6
           C+IK+T
Sbjct: 231 CFIKVT 236



>NP_001019246
          Length = 126

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CYIKITTRQ 9
          C+I  +TRQ
Sbjct: 79 CFILCSTRQ 87



>NP_078953
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CYIKITTRQ 9
           C++ I TR+
Sbjct: 500 CFLSILTRE 508



>XP_005249051
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CYIKITTRQ 9
           CY K  T+Q
Sbjct: 217 CYKKFVTQQ 225



>NP_005914
          Length = 1374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YIKITTRQ 9
           ++K+TT Q
Sbjct: 524 FVKLTTEQ 531



>NP_065928
          Length = 4427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    CYIKITT 7
            CY+ +TT
Sbjct: 1785 CYMTLTT 1791



>XP_005256527
          Length = 4427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    CYIKITT 7
            CY+ +TT
Sbjct: 1785 CYMTLTT 1791



>XP_005267049
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YIKITTRQ 9
           ++K+TT Q
Sbjct: 633 FVKLTTEQ 640



>XP_005267047
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YIKITTRQ 9
           ++K+TT Q
Sbjct: 633 FVKLTTEQ 640



>XP_006715545
          Length = 1483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YIKITTRQ 9
           ++K+TT Q
Sbjct: 633 FVKLTTEQ 640



>XP_005267048
          Length = 1484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YIKITTRQ 9
           ++K+TT Q
Sbjct: 633 FVKLTTEQ 640



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.139    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 385,807
Number of extensions: 570
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)