Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_113642                                                              18    1135
NP_000825                                                              16    5631
NP_775774                                                              16    5631
NP_001138405                                                           16    5631
NP_004658                                                              16    7355
XP_006724406                                                           16    7355
XP_006720790                                                           16    7355
XP_005268334                                                           16    7355
XP_005268333                                                           16    7355
XP_006720789                                                           16    7355
NP_002309                                                              15    9605
NP_996816                                                              15    9605
NP_443075                                                              15    9605
NP_001258152                                                           15    9605
NP_064610                                                              15    9605
NP_001092093                                                           15    9605
NP_066973                                                              15    9605
NP_001171545                                                           15    9605
NP_001092284                                                           15    9605
XP_005268816                                                           15    9605
XP_005268815                                                           15    9605
XP_005268814                                                           15    9605
XP_005268813                                                           15    9605
XP_005268812                                                           15    9605
XP_005268811                                                           15    9605
XP_005263199                                                           15    9605
XP_006711892                                                           15    9605
XP_006711891                                                           15    9605
XP_006711890                                                           15    9605
XP_006711889                                                           15    9605
XP_005273367                                                           15    9605
XP_005273366                                                           15    9605
XP_006711888                                                           15    9605
XP_006711887                                                           15    9605
XP_005273364                                                           15    9605
XP_005273362                                                           15    9605
XP_005273361                                                           15    9605
XP_006711886                                                           15    9605
XP_006711885                                                           15    9605
XP_005273359                                                           15    9605
XP_006711884                                                           15    9605
XP_005273357                                                           15    9605
XP_005273356                                                           15    9605
XP_005273358                                                           15    9605
XP_005273355                                                           15    9605
XP_005273353                                                           15    9605
XP_005273352                                                           15    9605
XP_005273354                                                           15    9605
XP_005273349                                                           15    9605
XP_006711883                                                           15    9605
XP_005273350                                                           15    9605
XP_005273351                                                           15    9605
XP_006711882                                                           15    9605
XP_005273348                                                           15    9605
XP_005273346                                                           15    9605
XP_005273347                                                           15    9605
XP_005273345                                                           15    9605
XP_005273344                                                           15    9605
NP_001005496                                                           15    9605
NP_955631                                                              15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    TTSEATVI 9
            TTSEATVI
Sbjct: 1087 TTSEATVI 1094
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TTSEATVI 9
           TTSEATVI
Sbjct: 882 TTSEATVI 889
>NP_113642
          Length = 669

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CTTSEATVI 9
           C TSE+TV+
Sbjct: 219 CVTSESTVV 227
>NP_000825
          Length = 1484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CTTSEATVI 9
           CT  EAT I
Sbjct: 232 CTKEEATYI 240
>NP_775774
          Length = 438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CTTSEATVI 9
           CT ++AT I
Sbjct: 319 CTVADATAI 327
>NP_001138405
          Length = 490

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CTTSEATVI 9
           CT ++AT I
Sbjct: 371 CTVADATAI 379
>NP_004658
          Length = 4834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CTTSEAT 7
            C++SEAT
Sbjct: 2429 CSSSEAT 2435
>XP_006724406
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TTSEATVI 9
          TT++ATV+
Sbjct: 18 TTTQATVV 25
>XP_006720790
          Length = 4748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CTTSEAT 7
            C++SEAT
Sbjct: 2343 CSSSEAT 2349
>XP_005268334
          Length = 4796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CTTSEAT 7
            C++SEAT
Sbjct: 2391 CSSSEAT 2397
>XP_005268333
          Length = 4796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CTTSEAT 7
            C++SEAT
Sbjct: 2391 CSSSEAT 2397
>XP_006720789
          Length = 4829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CTTSEAT 7
            C++SEAT
Sbjct: 2424 CSSSEAT 2430
>NP_002309
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CTTSEATV 8
           CT +EAT+
Sbjct: 128 CTGNEATL 135
>NP_996816
          Length = 5202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CTTSEAT 7
            CT SEA+
Sbjct: 2226 CTVSEAS 2232
>NP_443075
          Length = 6620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>NP_001258152
          Length = 8923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>NP_064610
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CTTSEATVI 9
           C TS  TV+
Sbjct: 603 CNTSSETVL 611
>NP_001092093
          Length = 7968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>NP_066973
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTTSEAT 7
           CT +EAT
Sbjct: 312 CTLAEAT 318
>NP_001171545
          Length = 1061

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTTSEAT 7
           CT +EAT
Sbjct: 312 CTLAEAT 318
>NP_001092284
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TTSEATVI 9
           TTSE TV+
Sbjct: 130 TTSEFTVL 137
>XP_005268816
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTTSEAT 7
           CT +EAT
Sbjct: 313 CTLAEAT 319
>XP_005268815
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTTSEAT 7
           CT +EAT
Sbjct: 313 CTLAEAT 319
>XP_005268814
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTTSEAT 7
           CT +EAT
Sbjct: 286 CTLAEAT 292
>XP_005268813
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTTSEAT 7
           CT +EAT
Sbjct: 313 CTLAEAT 319
>XP_005268812
          Length = 1128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTTSEAT 7
           CT +EAT
Sbjct: 313 CTLAEAT 319
>XP_005268811
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTTSEAT 7
           CT +EAT
Sbjct: 313 CTLAEAT 319
>XP_005263199
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CTTSEATVI 9
           C TS  TV+
Sbjct: 603 CNTSSETVL 611
>XP_006711892
          Length = 6865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711891
          Length = 8925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711890
          Length = 6957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711889
          Length = 7297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273367
          Length = 7677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273366
          Length = 7678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711888
          Length = 8059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711887
          Length = 8499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273364
          Length = 8653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273362
          Length = 8675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273361
          Length = 8763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711886
          Length = 8833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711885
          Length = 8835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273359
          Length = 8843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711884
          Length = 8847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273357
          Length = 8851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273356
          Length = 8851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273358
          Length = 8851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273355
          Length = 8924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273353
          Length = 8935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273352
          Length = 8935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273354
          Length = 8935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273349
          Length = 8939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711883
          Length = 8939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273350
          Length = 8939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273351
          Length = 8939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_006711882
          Length = 8977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 769 CETSEAHV 776
>XP_005273348
          Length = 9015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273346
          Length = 9026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273347
          Length = 9026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273345
          Length = 9026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>XP_005273344
          Length = 9027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CTTSEATV 8
           C TSEA V
Sbjct: 819 CETSEAHV 826
>NP_001005496
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TTSEAT 7
          TTSEAT
Sbjct: 8  TTSEAT 13
>NP_955631
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TTSEAT 7
           TTSEAT
Sbjct: 175 TTSEAT 180
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.113    0.316 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 324,586
Number of extensions: 479
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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