Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_079437                                                              18    1935
XP_006722175                                                           18    1935
XP_006722174                                                           18    1935
NP_001075019                                                           17    3301
NP_060639                                                              17    3301
XP_006724836                                                           17    3301
XP_005262507                                                           17    3301
XP_006724835                                                           17    3301
XP_006724834                                                           17    3301
XP_006724833                                                           17    3301
XP_006724832                                                           17    3301
XP_006724831                                                           17    3301
XP_006724830                                                           17    3301
XP_005262504                                                           17    3301
XP_006719162                                                           17    3301
XP_005253462                                                           17    3301
NP_001157745                                                           17    4312
NP_001074010                                                           17    4312
XP_006720508                                                           17    4312
XP_006720507                                                           17    4312
XP_005254310                                                           17    4312
XP_005254309                                                           17    4312
XP_005254306                                                           17    4312
XP_005254305                                                           17    4312
XP_005254304                                                           17    4312
XP_005254303                                                           17    4312
XP_006720506                                                           17    4312
XP_005254302                                                           17    4312
XP_005254301                                                           17    4312
XP_006720505                                                           17    4312
XP_005254300                                                           17    4312
NP_001155178                                                           16    5631
NP_000135                                                              16    5631
NP_852090                                                              16    5631
NP_005573                                                              16    5631
NP_073153                                                              16    7355
XP_006726452                                                           16    7355
XP_006712754                                                           16    7355
XP_006712753                                                           16    7355
XP_006712225                                                           16    7355
NP_003346                                                              15    9605
NP_705838                                                              15    9605
NP_116584                                                              15    9605
NP_004750                                                              15    9605
NP_057653                                                              15    9605
NP_005987                                                              15    9605
NP_660333                                                              15    9605
NP_001139659                                                           15    9605
NP_001139658                                                           15    9605
NP_001139656                                                           15    9605
NP_006201                                                              15    9605
NP_001139657                                                           15    9605
NP_149025                                                              15    9605
NP_065875                                                              15    9605
XP_005259549                                                           15    9605
XP_005252604                                                           15    9605
XP_005252603                                                           15    9605
XP_005252601                                                           15    9605
XP_006717551                                                           15    9605
XP_005252600                                                           15    9605
XP_005252599                                                           15    9605
XP_006717550                                                           15    9605
XP_005247408                                                           15    9605
XP_005247407                                                           15    9605
XP_005273410                                                           15    9605
NP_001122107                                                           15    9605
NP_001122105                                                           15    9605
NP_056487                                                              15    9605
NP_055190                                                              15    9605
>NP_079437
          Length = 881

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   CTEREASS 8
           CTE EASS
Sbjct: 852 CTEDEASS 859
>XP_006722175
          Length = 730

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   CTEREASS 8
           CTE EASS
Sbjct: 701 CTEDEASS 708
>XP_006722174
          Length = 743

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   CTEREASS 8
           CTE EASS
Sbjct: 714 CTEDEASS 721
>NP_001075019
          Length = 1593

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>NP_060639
          Length = 1747

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    CTEREASS 8
            CTERE+ S
Sbjct: 1589 CTERESIS 1596
>XP_006724836
          Length = 1582

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CTEREAS 7
           CTE EAS
Sbjct: 971 CTENEAS 977
>XP_005262507
          Length = 1594

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>XP_006724835
          Length = 1615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>XP_006724834
          Length = 1615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>XP_006724833
          Length = 1620

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>XP_006724832
          Length = 1640

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>XP_006724831
          Length = 1640

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>XP_006724830
          Length = 1642

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>XP_005262504
          Length = 1642

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    CTEREAS 7
            CTE EAS
Sbjct: 1031 CTENEAS 1037
>XP_006719162
          Length = 1676

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    CTEREASS 8
            CTERE+ S
Sbjct: 1589 CTERESIS 1596
>XP_005253462
          Length = 1747

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    CTEREASS 8
            CTERE+ S
Sbjct: 1589 CTERESIS 1596
>NP_001157745
          Length = 3065

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>NP_001074010
          Length = 2856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_006720508
          Length = 2658

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CTEREASST 9
           C E E+SST
Sbjct: 856 CNEGESSST 864
>XP_006720507
          Length = 2763

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CTEREASST 9
           C E E+SST
Sbjct: 961 CNEGESSST 969
>XP_005254310
          Length = 2906

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_005254309
          Length = 2956

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_005254306
          Length = 3066

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_005254305
          Length = 3114

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_005254304
          Length = 3115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_005254303
          Length = 3115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_006720506
          Length = 3115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_005254302
          Length = 3115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_005254301
          Length = 3115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_006720505
          Length = 3115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>XP_005254300
          Length = 3115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CTEREASST 9
            C E E+SST
Sbjct: 1313 CNEGESSST 1321
>NP_001155178
          Length = 171

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CTEREASS 8
          CT R ASS
Sbjct: 50 CTPRRASS 57
>NP_000135
          Length = 210

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CTEREASS 8
          CT R ASS
Sbjct: 50 CTPRRASS 57
>NP_852090
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CTEREASS 8
          CT R ASS
Sbjct: 50 CTPRRASS 57
>NP_005573
          Length = 661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CTEREASST 9
          C E+EA+ T
Sbjct: 28 CIEKEANKT 36
>NP_073153
          Length = 1944

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CTEREASS 8
            CT+RE+ S
Sbjct: 1288 CTDRESYS 1295
>XP_006726452
          Length = 272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CTEREASS 8
          CT+RE+ S
Sbjct: 86 CTDRESYS 93
>XP_006712754
          Length = 1784

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CTEREASS 8
            CT+RE+ S
Sbjct: 1128 CTDRESYS 1135
>XP_006712753
          Length = 1846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CTEREASS 8
            CT+RE+ S
Sbjct: 1190 CTDRESYS 1197
>XP_006712225
          Length = 272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CTEREASS 8
          CT+RE+ S
Sbjct: 86 CTDRESYS 93
>NP_003346
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CTEREA 6
           CT REA
Sbjct: 302 CTSREA 307
>NP_705838
          Length = 4069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EREASST 9
            EREASS+
Sbjct: 1139 EREASSS 1145
>NP_116584
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TEREAS 7
           TEREAS
Sbjct: 159 TEREAS 164
>NP_004750
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TEREAS 7
           TEREAS
Sbjct: 159 TEREAS 164
>NP_057653
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CTEREASST 9
           C E+EA+++
Sbjct: 711 CAEKEAATS 719
>NP_005987
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CTEREASST 9
           C E+EA+++
Sbjct: 691 CAEKEAATS 699
>NP_660333
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CTEREASS 8
            CT + ASS
Sbjct: 1098 CTNKSASS 1105
>NP_001139659
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    CTEREASST 9
            CTE   SST
Sbjct: 1386 CTETFTSST 1394
>NP_001139658
          Length = 1588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    CTEREASST 9
            CTE   SST
Sbjct: 1510 CTETFTSST 1518
>NP_001139656
          Length = 1588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    CTEREASST 9
            CTE   SST
Sbjct: 1510 CTETFTSST 1518
>NP_006201
          Length = 1588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    CTEREASST 9
            CTE   SST
Sbjct: 1510 CTETFTSST 1518
>NP_001139657
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    CTEREASST 9
            CTE   SST
Sbjct: 1384 CTETFTSST 1392
>NP_149025
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CTEREA 6
           C EREA
Sbjct: 316 CVEREA 321
>NP_065875
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EREASST 9
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005259549
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CTEREASS 8
           C+E +ASS
Sbjct: 674 CSEAQASS 681
>XP_005252604
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EREASST 9
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005252603
          Length = 1457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EREASST 9
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005252601
          Length = 1948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EREASST 9
           ER+ASST
Sbjct: 778 ERKASST 784
>XP_006717551
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EREASST 9
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005252600
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EREASST 9
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005252599
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EREASST 9
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_006717550
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EREASST 9
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005247408
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CTEREASS 8
          CT+ +ASS
Sbjct: 68 CTKSQASS 75
>XP_005247407
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CTEREASS 8
           CT+ +ASS
Sbjct: 151 CTKSQASS 158
>XP_005273410
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TEREAS 7
           TEREAS
Sbjct: 159 TEREAS 164
>NP_001122107
          Length = 1639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTEREAS 7
           C ER+AS
Sbjct: 647 CQERDAS 653
>NP_001122105
          Length = 1639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTEREAS 7
           C ER+AS
Sbjct: 647 CQERDAS 653
>NP_056487
          Length = 1639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CTEREAS 7
           C ER+AS
Sbjct: 647 CQERDAS 653
>NP_055190
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CTEREASS 8
           CT+ +ASS
Sbjct: 216 CTKSQASS 223
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.101    0.269 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 461,490
Number of extensions: 563
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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