Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              21     229
XP_005273257                                                           21     229
NP_872590                                                              17    3301
NP_002583                                                              17    3301
NP_871626                                                              16    5631
NP_005832                                                              16    5631
NP_955359                                                              16    5631
NP_001244967                                                           16    5631
NP_001244968                                                           16    5631
NP_055087                                                              16    5631
NP_002709                                                              16    5631
NP_003871                                                              16    5631
NP_001177376                                                           16    5631
NP_001253996                                                           16    5631
NP_937882                                                              16    5631
XP_005254194                                                           16    5631
XP_005262743                                                           16    5631
XP_006713749                                                           16    5631
XP_006712670                                                           16    5631
NP_071393                                                              16    5631
NP_001243718                                                           16    7355
NP_001243719                                                           16    7355
NP_005174                                                              16    7355
NP_001122312                                                           16    7355
NP_001122311                                                           16    7355
NP_000711                                                              16    7355
NP_005833                                                              16    7355
NP_000443                                                              16    7355
NP_001135918                                                           16    7355
NP_065208                                                              16    7355
NP_001193856                                                           16    7355
XP_006719816                                                           16    7355
XP_005266274                                                           16    7355
XP_006719815                                                           16    7355
XP_005273533                                                           16    7355
XP_006715067                                                           16    7355
XP_005265505                                                           16    7355
XP_006713388                                                           16    7355
NP_149420                                                              16    7355
NP_065210                                                              16    7355
NP_065209                                                              16    7355
NP_000028                                                              16    7355
NP_000072                                                              15    9605
NP_002205                                                              15    9605
NP_996562                                                              15    9605
NP_055181                                                              15    9605
NP_996561                                                              15    9605
NP_001005288                                                           15    9605
XP_005273087                                                           15    9605
XP_006711794                                                           15    9605
XP_005273086                                                           15    9605
XP_005273085                                                           15    9605
XP_005273084                                                           15    9605
NP_001004752                                                           15    9605
>NP_064450
          Length = 1722

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   CSRIIAMGV 9
           CSRIIAMG+
Sbjct: 562 CSRIIAMGL 570
>XP_005273257
          Length = 1726

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   CSRIIAMGV 9
           CSRIIAMG+
Sbjct: 562 CSRIIAMGL 570
>NP_872590
          Length = 261

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSRIIAMGV 9
          C R +AMGV
Sbjct: 62 CDRNLAMGV 70
>NP_002583
          Length = 261

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSRIIAMGV 9
          C R +AMGV
Sbjct: 62 CDRNLAMGV 70
>NP_871626
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           C R+ AMG+
Sbjct: 384 CERMEAMGI 392
>NP_005832
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSRIIAMG 8
           CSR + MG
Sbjct: 254 CSRYLCMG 261
>NP_955359
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSRIIAMG 8
           CSR + MG
Sbjct: 254 CSRYLCMG 261
>NP_001244967
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSRIIAMG 8
           CSR + MG
Sbjct: 254 CSRYLCMG 261
>NP_001244968
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSRIIAMG 8
           CSR + MG
Sbjct: 254 CSRYLCMG 261
>NP_055087
          Length = 1686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CSRIIAMGV 9
           CSR   MGV
Sbjct: 550 CSRSCGMGV 558
>NP_002709
          Length = 1150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R+ AMG+
Sbjct: 1005 CERMEAMGI 1013
>NP_003871
          Length = 354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CSRIIAMGV 9
           CSR   MG+
Sbjct: 219 CSRTCGMGI 227
>NP_001177376
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           C R+ AMG+
Sbjct: 269 CERMEAMGI 277
>NP_001253996
          Length = 171

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSRIIAMG 8
           C R++AMG
Sbjct: 97  CFRLMAMG 104
>NP_937882
          Length = 372

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CSRIIAMGV 9
           CSR   MG+
Sbjct: 237 CSRTCGMGI 245
>XP_005254194
          Length = 1689

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CSRIIAMGV 9
           CSR   MGV
Sbjct: 550 CSRSCGMGV 558
>XP_005262743
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSRIIAMG 8
           CSR + MG
Sbjct: 254 CSRYLCMG 261
>XP_006713749
          Length = 1150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R+ AMG+
Sbjct: 1005 CERMEAMGI 1013
>XP_006712670
          Length = 138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSRIIAMG 8
           C R++AMG
Sbjct: 97  CFRLMAMG 104
>NP_071393
          Length = 349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CSRIIAMG 8
           C R++A+G
Sbjct: 123 CCRVLALG 130
>NP_001243718
          Length = 1966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R++AM +
Sbjct: 1494 CKRLVAMNM 1502
>NP_001243719
          Length = 1912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R++AM +
Sbjct: 1440 CKRLVAMNM 1448
>NP_005174
          Length = 1977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R++AM +
Sbjct: 1505 CKRLVAMNM 1513
>NP_001122312
          Length = 2161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R++AM +
Sbjct: 1528 CKRLVAMNM 1536
>NP_001122311
          Length = 2137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R++AM +
Sbjct: 1513 CKRLVAMNM 1521
>NP_000711
          Length = 2181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R++AM +
Sbjct: 1548 CKRLVAMNM 1556
>NP_005833
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           C+R  AMGV
Sbjct: 250 CTRWSAMGV 258
>NP_000443
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CSRIIAMGV 9
           CS ++A+G+
Sbjct: 132 CSTLLALGM 140
>NP_001135918
          Length = 1897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SRIIAMG 8
            SRIIA+G
Sbjct: 1014 SRIIALG 1020
>NP_065208
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SRIIAMG 8
           SRIIA+G
Sbjct: 973 SRIIALG 979
>NP_001193856
          Length = 4707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CSRIIA 6
            CSR+IA
Sbjct: 2909 CSRVIA 2914
>XP_006719816
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           C+R  AMGV
Sbjct: 250 CTRWSAMGV 258
>XP_005266274
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           C+R  AMGV
Sbjct: 250 CTRWSAMGV 258
>XP_006719815
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           C+R  AMGV
Sbjct: 250 CTRWSAMGV 258
>XP_005273533
          Length = 1921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SRIIAMG 8
            SRIIA+G
Sbjct: 1014 SRIIALG 1020
>XP_006715067
          Length = 4707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CSRIIA 6
            CSR+IA
Sbjct: 2909 CSRVIA 2914
>XP_005265505
          Length = 2146

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R++AM +
Sbjct: 1513 CKRLVAMNM 1521
>XP_006713388
          Length = 2194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CSRIIAMGV 9
            C R++AM +
Sbjct: 1561 CKRLVAMNM 1569
>NP_149420
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRIIAMGV 9
           +R+IA+GV
Sbjct: 137 TRVIALGV 144
>NP_065210
          Length = 1719

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SRIIAMG 8
           SRIIA+G
Sbjct: 973 SRIIALG 979
>NP_065209
          Length = 1881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SRIIAMG 8
           SRIIA+G
Sbjct: 973 SRIIALG 979
>NP_000028
          Length = 1880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SRIIAMG 8
           SRIIA+G
Sbjct: 973 SRIIALG 979
>NP_000072
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CSRIIAMGV 9
            C++I+ +G+
Sbjct: 1371 CTKILLLGI 1379
>NP_002205
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  CSRIIAMG 8
          C+R +A+G
Sbjct: 55 CARCLALG 62
>NP_996562
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           CS+ I +GV
Sbjct: 239 CSKAIRVGV 247
>NP_055181
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           CS+ I +GV
Sbjct: 251 CSKAIRVGV 259
>NP_996561
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSRIIAMGV 9
           CS+ I +GV
Sbjct: 239 CSKAIRVGV 247
>NP_001005288
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRIIAMGV 9
           +RI+AMG+
Sbjct: 141 NRILAMGL 148
>XP_005273087
          Length = 2788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CSRIIAMGV 9
            C++I+ +G+
Sbjct: 1371 CTKILLLGI 1379
>XP_006711794
          Length = 3022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   CSRIIAMGV 9
           C++I+ +G+
Sbjct: 592 CTKILLLGI 600
>XP_005273086
          Length = 3264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CSRIIAMGV 9
            C++I+ +G+
Sbjct: 1371 CTKILLLGI 1379
>XP_005273085
          Length = 3755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CSRIIAMGV 9
            C++I+ +G+
Sbjct: 1371 CTKILLLGI 1379
>XP_005273084
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CSRIIAMGV 9
            C++I+ +G+
Sbjct: 1371 CTKILLLGI 1379
>NP_001004752
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRIIAMGV 9
           SRII MG+
Sbjct: 141 SRIIQMGL 148
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.144    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 410,218
Number of extensions: 687
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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