Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_056099                                                              17    2528
XP_006710565                                                           17    2528
XP_006710564                                                           17    2528
XP_005270743                                                           17    2528
NP_001273700                                                           17    4312
NP_115593                                                              17    4312
NP_001028752                                                           17    4312
NP_079385                                                              17    4312
NP_001157207                                                           17    4312
NP_942592                                                              17    4312
NP_004961                                                              17    4312
XP_006725415                                                           17    4312
XP_006725414                                                           17    4312
XP_006722171                                                           17    4312
XP_006722170                                                           17    4312
XP_005265728                                                           17    4312
XP_005265724                                                           17    4312
NP_001139478                                                           17    4312
NP_001185882                                                           16    5631
NP_076976                                                              16    5631
NP_004557                                                              16    7355
NP_001138915                                                           16    7355
NP_001269559                                                           16    7355
NP_001243000                                                           16    7355
NP_004558                                                              16    7355
NP_078922                                                              16    7355
XP_005257603                                                           16    7355
XP_006722058                                                           16    7355
XP_005257602                                                           16    7355
XP_005252521                                                           16    7355
XP_005252520                                                           16    7355
XP_005272048                                                           16    7355
XP_006714680                                                           16    7355
XP_005265287                                                           16    7355
XP_006710961                                                           16    7355
NP_001035805                                                           16    7355
NP_116570                                                              15    9605
NP_116572                                                              15    9605
NP_116571                                                              15    9605
NP_116569                                                              15    9605
NP_001154803                                                           15    9605
NP_001154802                                                           15    9605
NP_061857                                                              15    9605
NP_004358                                                              15    9605
NP_113597                                                              15    9605
NP_065816                                                              15    9605
XP_006719529                                                           15    9605
XP_005269042                                                           15    9605
XP_005269041                                                           15    9605
XP_006716082                                                           15    9605
XP_006716081                                                           15    9605
XP_005250456                                                           15    9605
XP_006716080                                                           15    9605
XP_006716079                                                           15    9605
XP_006711445                                                           15    9605
XP_006711444                                                           15    9605
XP_006710573                                                           15    9605
XP_006710572                                                           15    9605
XP_006710571                                                           15    9605
XP_006710570                                                           15    9605
XP_006710569                                                           15    9605
XP_006710568                                                           15    9605
XP_006710567                                                           15    9605
XP_006710566                                                           15    9605
XP_005245859                                                           15    9605
NP_006203                                                              15    9605
NP_001018063                                                           15    9605
>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    CSLVALREF 9
            CSL ALREF
Sbjct: 1831 CSLDALREF 1839
>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    CSLVALREF 9
            CSL ALREF
Sbjct: 1831 CSLDALREF 1839
>NP_056099
          Length = 3375

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    CSLVALRE 8
            CSL ALRE
Sbjct: 1187 CSLEALRE 1194
>XP_006710565
          Length = 3140

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           CSL ALRE
Sbjct: 952 CSLEALRE 959
>XP_006710564
          Length = 3432

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    CSLVALRE 8
            CSL ALRE
Sbjct: 1244 CSLEALRE 1251
>XP_005270743
          Length = 3453

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    CSLVALRE 8
            CSL ALRE
Sbjct: 1265 CSLEALRE 1272
>NP_001273700
          Length = 2490

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    CSLVALREF 9
            C++ A+REF
Sbjct: 1633 CNINAIREF 1641
>NP_115593
          Length = 2603

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    CSLVALREF 9
            C++ A+REF
Sbjct: 1746 CNINAIREF 1754
>NP_001028752
          Length = 317

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          C+LVAL  F
Sbjct: 70 CTLVALNPF 78
>NP_079385
          Length = 770

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          C+LVAL  F
Sbjct: 70 CTLVALNPF 78
>NP_001157207
          Length = 970

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          C+LVAL  F
Sbjct: 70 CTLVALNPF 78
>NP_942592
          Length = 2352

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    CSLVALREF 9
            C++ A+REF
Sbjct: 1495 CNINAIREF 1503
>NP_004961
          Length = 605

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CSLVALREF 9
           C L ALR+F
Sbjct: 542 CPLKALRDF 550
>XP_006725415
          Length = 990

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          C+LVAL  F
Sbjct: 70 CTLVALNPF 78
>XP_006725414
          Length = 1034

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          C+LVAL  F
Sbjct: 70 CTLVALNPF 78
>XP_006722171
          Length = 972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          C+LVAL  F
Sbjct: 70 CTLVALNPF 78
>XP_006722170
          Length = 1016

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          C+LVAL  F
Sbjct: 70 CTLVALNPF 78
>XP_005265728
          Length = 2351

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    CSLVALREF 9
            C++ A+REF
Sbjct: 1494 CNINAIREF 1502
>XP_005265724
          Length = 2602

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    CSLVALREF 9
            C++ A+REF
Sbjct: 1745 CNINAIREF 1753
>NP_001139478
          Length = 643

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CSLVALREF 9
           C L ALR+F
Sbjct: 580 CPLKALRDF 588
>NP_001185882
          Length = 252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   CSLVALRE 8
           C+LV+L+E
Sbjct: 99  CALVSLKE 106
>NP_076976
          Length = 234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   CSLVALRE 8
           C+LV+L+E
Sbjct: 99  CALVSLKE 106
>NP_004557
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           C+L ALR+
Sbjct: 102 CALAALRD 109
>NP_001138915
          Length = 500

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CSLVALRE 8
          C+L ALR+
Sbjct: 82 CALAALRD 89
>NP_001269559
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           C+L ALR+
Sbjct: 116 CALAALRD 123
>NP_001243000
          Length = 5207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CSLVALRE 8
            CS V+LR+
Sbjct: 2633 CSFVSLRD 2640
>NP_004558
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           C+L ALR+
Sbjct: 106 CALAALRD 113
>NP_078922
          Length = 744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CSLVALREF 9
           C +VA R F
Sbjct: 643 CEMVAYRSF 651
>XP_005257603
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CSLVALRE 8
            CS V+LR+
Sbjct: 2682 CSFVSLRD 2689
>XP_006722058
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CSLVALRE 8
            CS V+LR+
Sbjct: 2682 CSFVSLRD 2689
>XP_005257602
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CSLVALRE 8
            CS V+LR+
Sbjct: 2682 CSFVSLRD 2689
>XP_005252521
          Length = 462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           C+L ALR+
Sbjct: 102 CALAALRD 109
>XP_005252520
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           C+L ALR+
Sbjct: 102 CALAALRD 109
>XP_005272048
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   CSLVAL 6
           CSLVAL
Sbjct: 697 CSLVAL 702
>XP_006714680
          Length = 1002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   CSLVAL 6
           CSLVAL
Sbjct: 848 CSLVAL 853
>XP_005265287
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           C+L ALR+
Sbjct: 106 CALAALRD 113
>XP_006710961
          Length = 740

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CSLVALREF 9
           C +VA R F
Sbjct: 639 CEMVAYRSF 647
>NP_001035805
          Length = 471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           C LVALR
Sbjct: 138 CMLVALR 144
>NP_116570
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 787 CSLPALR 793
>NP_116572
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 785 CSLPALR 791
>NP_116571
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 804 CSLPALR 810
>NP_116569
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 806 CSLPALR 812
>NP_001154803
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSLVALREF 9
           C+L  L+EF
Sbjct: 297 CNLKELKEF 305
>NP_001154802
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSLVALREF 9
           C+L  L+EF
Sbjct: 286 CNLKELKEF 294
>NP_061857
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSLVALREF 9
           C+L  L+EF
Sbjct: 286 CNLKELKEF 294
>NP_004358
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          CSL  +R+F
Sbjct: 36 CSLQEVRQF 44
>NP_113597
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CSLVALREF 9
          CSL  +R+F
Sbjct: 36 CSLQEVRQF 44
>NP_065816
          Length = 5183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4394 CDLVALLE 4401
>XP_006719529
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSLVALREF 9
           C+L  L+EF
Sbjct: 160 CNLKELKEF 168
>XP_005269042
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSLVALREF 9
           C+L  L+EF
Sbjct: 206 CNLKELKEF 214
>XP_005269041
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSLVALREF 9
           C+L  L+EF
Sbjct: 286 CNLKELKEF 294
>XP_006716082
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 665 CSLPALR 671
>XP_006716081
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 692 CSLPALR 698
>XP_005250456
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 832 CSLPALR 838
>XP_006716080
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 840 CSLPALR 846
>XP_006716079
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSLVALR 7
           CSL ALR
Sbjct: 858 CSLPALR 864
>XP_006711445
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CSLVALRE 8
          C+LVAL +
Sbjct: 7  CALVALED 14
>XP_006711444
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CSLVALRE 8
          C+LVAL +
Sbjct: 7  CALVALED 14
>XP_006710573
          Length = 5177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4388 CDLVALLE 4395
>XP_006710572
          Length = 5188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4399 CDLVALLE 4406
>XP_006710571
          Length = 5194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4405 CDLVALLE 4412
>XP_006710570
          Length = 5195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4406 CDLVALLE 4413
>XP_006710569
          Length = 5212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4423 CDLVALLE 4430
>XP_006710568
          Length = 5221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4432 CDLVALLE 4439
>XP_006710567
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4433 CDLVALLE 4440
>XP_006710566
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4433 CDLVALLE 4440
>XP_005245859
          Length = 5223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CSLVALRE 8
            C LVAL E
Sbjct: 4434 CDLVALLE 4441
>NP_006203
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           C+LVAL +
Sbjct: 105 CALVALED 112
>NP_001018063
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CSLVALRE 8
           C+LVAL +
Sbjct: 105 CALVALED 112
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.144    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 467,638
Number of extensions: 991
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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