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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           20     299
NP_000170                                                              20     299
NP_001268422                                                           20     299
NP_001268423                                                           20     299
XP_005264328                                                           20     299
NP_734465                                                              17    2528
NP_001231818                                                           17    2528
XP_006717416                                                           17    2528
NP_000278                                                              17    3301
NP_612353                                                              17    3301
NP_001194003                                                           17    3301
NP_001194001                                                           17    3301
NP_001194002                                                           17    3301
XP_005249237                                                           17    3301
NP_001194000                                                           17    3301
NP_000341                                                              17    4312
NP_055365                                                              17    4312
NP_001034678                                                           17    4312
NP_001375                                                              17    4312
XP_005270616                                                           17    4312
NP_079133                                                              16    7355
NP_116245                                                              16    7355
XP_006720787                                                           16    7355
NP_001122108                                                           15    9605
NP_057222                                                              15    9605
NP_001177912                                                           15    9605
NP_005112                                                              15    9605
XP_005255090                                                           15    9605
XP_006715792                                                           15    9605
XP_006715791                                                           15    9605
XP_006715790                                                           15    9605
XP_006715789                                                           15    9605
XP_006715788                                                           15    9605

>NP_001268421
          Length = 1230

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CRPVILLSE 9
           CRPVILL E
Sbjct: 945 CRPVILLPE 953



>NP_000170
          Length = 1360

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    CRPVILLSE 9
            CRPVILL E
Sbjct: 1075 CRPVILLPE 1083



>NP_001268422
          Length = 1058

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CRPVILLSE 9
           CRPVILL E
Sbjct: 773 CRPVILLPE 781



>NP_001268423
          Length = 1058

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CRPVILLSE 9
           CRPVILL E
Sbjct: 773 CRPVILLPE 781



>XP_005264328
          Length = 1261

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CRPVILLSE 9
           CRPVILL E
Sbjct: 976 CRPVILLPE 984



>NP_734465
          Length = 945

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   CRPVIL 6
           CRPVIL
Sbjct: 615 CRPVIL 620



>NP_001231818
          Length = 934

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   CRPVIL 6
           CRPVIL
Sbjct: 604 CRPVIL 609



>XP_006717416
          Length = 624

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   CRPVILLS 8
           CRPV+L S
Sbjct: 503 CRPVVLHS 510



>NP_000278
          Length = 980

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CRPVILL 7
           CRP +LL
Sbjct: 521 CRPAVLL 527



>NP_612353
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CRPVIL 6
           CRPV+L
Sbjct: 329 CRPVVL 334



>NP_001194003
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CRPVIL 6
           CRPV+L
Sbjct: 267 CRPVVL 272



>NP_001194001
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CRPVIL 6
           CRPV+L
Sbjct: 267 CRPVVL 272



>NP_001194002
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CRPVIL 6
           CRPV+L
Sbjct: 267 CRPVVL 272



>XP_005249237
          Length = 892

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CRPVILL 7
           CRP +LL
Sbjct: 433 CRPAVLL 439



>NP_001194000
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CRPVIL 6
           CRPV+L
Sbjct: 267 CRPVVL 272



>NP_000341
          Length = 2273

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    CRPVILLSE 9
            C P++LL E
Sbjct: 2088 CPPLVLLDE 2096



>NP_055365
          Length = 1032

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RPVILLSE 9
           RPV+LL E
Sbjct: 846 RPVVLLPE 853



>NP_001034678
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVILLSE 9
           PV+LLSE
Sbjct: 148 PVVLLSE 154



>NP_001375
          Length = 489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVILLSE 9
           PV+LLSE
Sbjct: 148 PVVLLSE 154



>XP_005270616
          Length = 413

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  PVILLSE 9
          PV+LLSE
Sbjct: 72 PVVLLSE 78



>NP_079133
          Length = 1844

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CRPVILLSE 9
           CR V+ LSE
Sbjct: 210 CRDVVDLSE 218



>NP_116245
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CRPVILLS 8
           CRP  LLS
Sbjct: 352 CRPRTLLS 359



>XP_006720787
          Length = 256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CRPVILLS 8
           CRP  LLS
Sbjct: 230 CRPRTLLS 237



>NP_001122108
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVILLSE 9
           P++LLSE
Sbjct: 597 PLVLLSE 603



>NP_057222
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CRPVILLSE 9
           CR  I LSE
Sbjct: 207 CRVAIYLSE 215



>NP_001177912
          Length = 179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CRPVILLSE 9
           CR  I LSE
Sbjct: 169 CRVAIYLSE 177



>NP_005112
          Length = 2174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RPVILLSE 9
           +PV LLSE
Sbjct: 184 QPVYLLSE 191



>XP_005255090
          Length = 203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CRPVILLSE 9
           CR  I LSE
Sbjct: 193 CRVAIYLSE 201



>XP_006715792
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVILLSE 9
           P++LLSE
Sbjct: 597 PLVLLSE 603



>XP_006715791
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVILLSE 9
           P++LLSE
Sbjct: 597 PLVLLSE 603



>XP_006715790
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVILLSE 9
           P++LLSE
Sbjct: 597 PLVLLSE 603



>XP_006715789
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVILLSE 9
           P++LLSE
Sbjct: 597 PLVLLSE 603



>XP_006715788
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVILLSE 9
           P++LLSE
Sbjct: 597 PLVLLSE 603



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.148    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 541,495
Number of extensions: 802
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)