Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_003900                                                              17    3301
XP_005251150                                                           17    3301
NP_775871                                                              17    4312
NP_002579                                                              17    4312
NP_115778                                                              17    4312
NP_612422                                                              16    5631
NP_055759                                                              16    7355
NP_659429                                                              16    7355
NP_031363                                                              16    7355
NP_031361                                                              16    7355
NP_110448                                                              16    7355
NP_001009566                                                           16    7355
XP_006724351                                                           16    7355
XP_006724350                                                           16    7355
XP_006713504                                                           16    7355
XP_006713503                                                           16    7355
XP_005265688                                                           16    7355
XP_006713502                                                           16    7355
XP_006713501                                                           16    7355
XP_006713500                                                           16    7355
XP_005265687                                                           16    7355
XP_006712420                                                           16    7355
XP_006712419                                                           16    7355
XP_005263954                                                           16    7355
XP_005263489                                                           16    7355
NP_945345                                                              15    9605
NP_038464                                                              15    9605
NP_995314                                                              15    9605
NP_055290                                                              15    9605
NP_001035847                                                           15    9605
NP_005867                                                              15    9605
NP_005125                                                              15    9605
NP_114119                                                              15    9605
XP_006726599                                                           15    9605
XP_005258805                                                           15    9605
XP_006719013                                                           15    9605
XP_005249698                                                           15    9605
XP_006713840                                                           15    9605
XP_006713839                                                           15    9605
XP_006712264                                                           15    9605
XP_006712263                                                           15    9605
XP_006712257                                                           15    9605
XP_006712256                                                           15    9605
XP_005246298                                                           15    9605
XP_005246297                                                           15    9605
XP_005246299                                                           15    9605
XP_006712255                                                           15    9605
XP_005246296                                                           15    9605
XP_006712254                                                           15    9605
XP_005246295                                                           15    9605
XP_006712253                                                           15    9605
XP_006712252                                                           15    9605
XP_005246294                                                           15    9605
XP_006712251                                                           15    9605
XP_005246293                                                           15    9605
XP_005246292                                                           15    9605
XP_006712250                                                           15    9605
XP_001715329                                                           15    9605
NP_001129396                                                           15    9605
NP_055643                                                              15    9605
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           QVTVELTV
Sbjct: 116 QVTVELTV 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CQVTVE 6
            CQVTV+
Sbjct: 1114 CQVTVD 1119
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           QVTVELTV
Sbjct: 116 QVTVELTV 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CQVTVE 6
            CQVTV+
Sbjct: 1114 CQVTVD 1119
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           QVTVELTV
Sbjct: 116 QVTVELTV 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CQVTVE 6
            CQVTV+
Sbjct: 1183 CQVTVD 1188
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           QVTVELTV
Sbjct: 116 QVTVELTV 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CQVTVE 6
            CQVTV+
Sbjct: 1183 CQVTVD 1188
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           QVTVELTV
Sbjct: 126 QVTVELTV 133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CQVTVE 6
            CQVTV+
Sbjct: 1124 CQVTVD 1129
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           QVTVELTV
Sbjct: 126 QVTVELTV 133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CQVTVE 6
            CQVTV+
Sbjct: 1193 CQVTVD 1198
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           QVTVELTV
Sbjct: 126 QVTVELTV 133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CQVTVE 6
            CQVTV+
Sbjct: 1193 CQVTVD 1198
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           QVTVELTV
Sbjct: 126 QVTVELTV 133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CQVTVE 6
            CQVTV+
Sbjct: 1193 CQVTVD 1198
>NP_003900
          Length = 537

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQVTVELT 8
           C++TVE T
Sbjct: 272 CEITVECT 279
>XP_005251150
          Length = 537

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQVTVELT 8
           C++TVE T
Sbjct: 272 CEITVECT 279
>NP_775871
          Length = 8384

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    CQVTVELTV 9
            CQ+ ++LT+
Sbjct: 1165 CQIPIDLTL 1173
>NP_002579
          Length = 934

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CQVTVELTV 9
           C VT+EL V
Sbjct: 104 CTVTLELVV 112
>NP_115778
          Length = 863

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CQVTVELTV 9
           C VT+EL V
Sbjct: 104 CTVTLELVV 112
>NP_612422
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QVTVELTV 9
           Q TVE+TV
Sbjct: 116 QATVEMTV 123
>NP_055759
          Length = 971

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CQVTVE 6
           C+VTVE
Sbjct: 710 CEVTVE 715
>NP_659429
          Length = 1294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           ++TVELTV
Sbjct: 210 KLTVELTV 217
>NP_031363
          Length = 1778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQVTVELT 8
            CQ+ +ELT
Sbjct: 1032 CQLKLELT 1039
>NP_031361
          Length = 1755

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQVTVELT 8
            CQ+ +ELT
Sbjct: 1032 CQLKLELT 1039
>NP_110448
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CQVTVEL 7
           C+ TVEL
Sbjct: 152 CETTVEL 158
>NP_001009566
          Length = 981

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CQVTVE 6
           C+VTVE
Sbjct: 720 CEVTVE 725
>XP_006724351
          Length = 221

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CQVTVELTV 9
           C++T+ LT+
Sbjct: 130 CRLTLHLTI 138
>XP_006724350
          Length = 271

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CQVTVELTV 9
           C++T+ LT+
Sbjct: 180 CRLTLHLTI 188
>XP_006713504
          Length = 1078

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQVTVELT 8
           CQ+ +ELT
Sbjct: 329 CQLKLELT 336
>XP_006713503
          Length = 1438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQVTVELT 8
            CQ+ +ELT
Sbjct: 1032 CQLKLELT 1039
>XP_005265688
          Length = 1480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQVTVELT 8
           CQ+ +ELT
Sbjct: 731 CQLKLELT 738
>XP_006713502
          Length = 1578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQVTVELT 8
            CQ+ +ELT
Sbjct: 1032 CQLKLELT 1039
>XP_006713501
          Length = 1727

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQVTVELT 8
            CQ+ +ELT
Sbjct: 1032 CQLKLELT 1039
>XP_006713500
          Length = 1746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQVTVELT 8
            CQ+ +ELT
Sbjct: 1032 CQLKLELT 1039
>XP_005265687
          Length = 1758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQVTVELT 8
            CQ+ +ELT
Sbjct: 1032 CQLKLELT 1039
>XP_006712420
          Length = 1162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QVTVELTV 9
          ++TVELTV
Sbjct: 60 KLTVELTV 67
>XP_006712419
          Length = 1308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           ++TVELTV
Sbjct: 210 KLTVELTV 217
>XP_005263954
          Length = 1312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           ++TVELTV
Sbjct: 210 KLTVELTV 217
>XP_005263489
          Length = 962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CQVTVE 6
           C+VTVE
Sbjct: 701 CEVTVE 706
>NP_945345
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VTVELTV 9
           VTVE+TV
Sbjct: 622 VTVEVTV 628
>NP_038464
          Length = 1128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQVTVELTV 9
           CQV  ++TV
Sbjct: 117 CQVFFDITV 125
>NP_995314
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQVTVELTV 9
           CQV  ++TV
Sbjct: 123 CQVFFDITV 131
>NP_055290
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CQVTVELT 8
           C +TV+L+
Sbjct: 228 CSITVQLS 235
>NP_001035847
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CQVTVELT 8
           C V +ELT
Sbjct: 174 CPVLIELT 181
>NP_005867
          Length = 3267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1475 CSVTLEL 1481
>NP_005125
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CQVTVELT 8
           C V +ELT
Sbjct: 157 CPVLIELT 164
>NP_114119
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CQVTVEL 7
           C+++VEL
Sbjct: 199 CEISVEL 205
>XP_006726599
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QVTVELTV 9
           Q TV+LT+
Sbjct: 481 QTTVQLTI 488
>XP_005258805
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CQVTVELT 8
           C +TV+L+
Sbjct: 116 CSITVQLS 123
>XP_006719013
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QVTVELTV 9
           Q TV+LT+
Sbjct: 426 QTTVQLTI 433
>XP_005249698
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVTVELTV 9
           +VT+E+TV
Sbjct: 625 RVTIEVTV 632
>XP_006713840
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CQVTVEL 7
           C+++VEL
Sbjct: 199 CEISVEL 205
>XP_006713839
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CQVTVEL 7
           C+++VEL
Sbjct: 199 CEISVEL 205
>XP_006712264
          Length = 1126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQVTVELTV 9
           CQV  ++TV
Sbjct: 115 CQVFFDITV 123
>XP_006712263
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQVTVELTV 9
           CQV  ++TV
Sbjct: 121 CQVFFDITV 129
>XP_006712257
          Length = 1718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1475 CSVTLEL 1481
>XP_006712256
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CQVTVEL 7
           C VT+EL
Sbjct: 626 CSVTLEL 632
>XP_005246298
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CQVTVEL 7
           C VT+EL
Sbjct: 626 CSVTLEL 632
>XP_005246297
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CQVTVEL 7
           C VT+EL
Sbjct: 626 CSVTLEL 632
>XP_005246299
          Length = 2480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CQVTVEL 7
           C VT+EL
Sbjct: 688 CSVTLEL 694
>XP_006712255
          Length = 2622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1475 CSVTLEL 1481
>XP_005246296
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CQVTVEL 7
           C VT+EL
Sbjct: 683 CSVTLEL 689
>XP_006712254
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CQVTVEL 7
           C VT+EL
Sbjct: 683 CSVTLEL 689
>XP_005246295
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1322 CSVTLEL 1328
>XP_006712253
          Length = 3117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1325 CSVTLEL 1331
>XP_006712252
          Length = 3163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1371 CSVTLEL 1377
>XP_005246294
          Length = 3173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1381 CSVTLEL 1387
>XP_006712251
          Length = 3176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1384 CSVTLEL 1390
>XP_005246293
          Length = 3206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1414 CSVTLEL 1420
>XP_005246292
          Length = 3208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1416 CSVTLEL 1422
>XP_006712250
          Length = 3248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQVTVEL 7
            C VT+EL
Sbjct: 1456 CSVTLEL 1462
>XP_001715329
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QVTVELTV 9
           Q TV+LT+
Sbjct: 426 QTTVQLTI 433
>NP_001129396
          Length = 1590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QVTVELTV 9
            +VT+E+TV
Sbjct: 1171 RVTIEVTV 1178
>NP_055643
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CQVTVE 6
           CQ TVE
Sbjct: 296 CQATVE 301
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.130    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 411,788
Number of extensions: 773
Number of successful extensions: 76
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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