Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_835739                                                              19     869
XP_005271345                                                           19     869
NP_116241                                                              19     869
NP_001273376                                                           17    2528
NP_055537                                                              17    2528
NP_001273375                                                           17    2528
NP_001273374                                                           17    2528
NP_056948                                                              17    2528
XP_006715344                                                           17    2528
XP_006715343                                                           17    2528
XP_006715342                                                           17    2528
XP_006715341                                                           17    2528
XP_006715340                                                           17    2528
XP_006715339                                                           17    2528
XP_006715338                                                           17    2528
NP_001092284                                                           17    3301
XP_006723678                                                           17    4312
NP_003236                                                              17    4312
NP_065976                                                              16    5631
NP_001265713                                                           16    5631
XP_005256986                                                           16    5631
XP_006710856                                                           16    5631
NP_001001557                                                           16    7355
NP_001096640                                                           16    7355
NP_066012                                                              16    7355
NP_001103233                                                           16    7355
NP_031375                                                              16    7355
NP_005225                                                              16    7355
XP_005255279                                                           16    7355
XP_005255190                                                           16    7355
XP_005249598                                                           16    7355
XP_005249596                                                           16    7355
XP_005249594                                                           16    7355
XP_005249593                                                           16    7355
XP_005263223                                                           16    7355
NP_001073886                                                           16    7355
NP_077719                                                              15    9605
NP_001159521                                                           15    9605
NP_060289                                                              15    9605
NP_001106995                                                           15    9605
NP_006837                                                              15    9605
NP_689908                                                              15    9605
NP_056169                                                              15    9605
NP_659441                                                              15    9605
XP_006726776                                                           15    9605
XP_006725181                                                           15    9605
XP_006725180                                                           15    9605
XP_005258694                                                           15    9605
XP_006722987                                                           15    9605
XP_006721688                                                           15    9605
XP_006716362                                                           15    9605
XP_006716361                                                           15    9605
XP_005247216                                                           15    9605
XP_005270959                                                           15    9605
XP_005270958                                                           15    9605
XP_006710730                                                           15    9605
XP_006710092                                                           15    9605
NP_001121170                                                           15    9605
NP_001121171                                                           15    9605
NP_060301                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    QSFVDRSL 9
            QSFVDRSL
Sbjct: 1817 QSFVDRSL 1824
>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    QSFVDRSL 9
            QSFVDRSL
Sbjct: 1817 QSFVDRSL 1824
>NP_835739
          Length = 458

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           CQSFVD S+
Sbjct: 349 CQSFVDVSI 357
>XP_005271345
          Length = 458

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           CQSFVD S+
Sbjct: 349 CQSFVDVSI 357
>NP_116241
          Length = 458

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           CQSFVD S+
Sbjct: 349 CQSFVDVSI 357
>NP_001273376
          Length = 613

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 546 CRSFLDGSL 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 35 CNSFIENS 42
>NP_055537
          Length = 1068

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 596 CRSFLDGSL 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 35 CNSFIENS 42
>NP_001273375
          Length = 647

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 580 CRSFLDGSL 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 69 CNSFIENS 76
>NP_001273374
          Length = 1047

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 575 CRSFLDGSL 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 64 CNSFIENS 71
>NP_056948
          Length = 591

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 546 CRSFLDGSL 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 35 CNSFIENS 42
>XP_006715344
          Length = 625

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 580 CRSFLDGSL 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 69 CNSFIENS 76
>XP_006715343
          Length = 1018

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 546 CRSFLDGSL 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 35 CNSFIENS 42
>XP_006715342
          Length = 1018

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 546 CRSFLDGSL 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 35 CNSFIENS 42
>XP_006715341
          Length = 1018

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 546 CRSFLDGSL 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 35 CNSFIENS 42
>XP_006715340
          Length = 1018

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 546 CRSFLDGSL 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 35 CNSFIENS 42
>XP_006715339
          Length = 1030

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 558 CRSFLDGSL 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 47 CNSFIENS 54
>XP_006715338
          Length = 1052

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CQSFVDRSL 9
           C+SF+D SL
Sbjct: 580 CRSFLDGSL 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          C SF++ S
Sbjct: 69 CNSFIENS 76
>NP_001092284
          Length = 473

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQSFVDRS 8
           CQ F+DR+
Sbjct: 211 CQWFIDRA 218
>XP_006723678
          Length = 718

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CQSFVDRSL 9
           C S +DRSL
Sbjct: 214 CLSILDRSL 222
>NP_003236
          Length = 693

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CQSFVDRSL 9
           C S +DRSL
Sbjct: 189 CLSILDRSL 197
>NP_065976
          Length = 1223

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQSFVDRSL 9
           C SF DR++
Sbjct: 839 CNSFSDRTV 847
>NP_001265713
          Length = 255

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          CQ  VDR+
Sbjct: 8  CQDLVDRT 15
>XP_005256986
          Length = 255

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  CQSFVDRS 8
          CQ  VDR+
Sbjct: 8  CQDLVDRT 15
>XP_006710856
          Length = 978

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQSFVDRSL 9
           C SF DR++
Sbjct: 594 CNSFSDRTV 602
>NP_001001557
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SFVDRSL 9
           SFVDR L
Sbjct: 129 SFVDRGL 135
>NP_001096640
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   CQSFVDR 7
           CQ  VDR
Sbjct: 203 CQQLVDR 209
>NP_066012
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CQSFVD 6
           CQ FVD
Sbjct: 120 CQHFVD 125
>NP_001103233
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CQSFVD 6
           C+SF+D
Sbjct: 120 CRSFID 125
>NP_031375
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 1   CQSFVD 6
           CQ F+D
Sbjct: 936 CQKFID 941
>NP_005225
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CQSFVDRSL 9
          C+SF  RS+
Sbjct: 76 CKSFFKRSI 84
>XP_005255279
          Length = 855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QSFVDRSL 9
           +SF+DRS+
Sbjct: 655 ESFLDRSV 662
>XP_005255190
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CQSFVD 6
           C+SF+D
Sbjct: 120 CRSFID 125
>XP_005249598
          Length = 1027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 1   CQSFVD 6
           CQ F+D
Sbjct: 889 CQKFID 894
>XP_005249596
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 1   CQSFVD 6
           CQ F+D
Sbjct: 902 CQKFID 907
>XP_005249594
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 1   CQSFVD 6
           CQ F+D
Sbjct: 902 CQKFID 907
>XP_005249593
          Length = 1074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 1   CQSFVD 6
           CQ F+D
Sbjct: 936 CQKFID 941
>XP_005263223
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CQSFVD 6
           CQ FVD
Sbjct: 120 CQHFVD 125
>NP_001073886
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QSFVDRSL 9
           +SF+DRS+
Sbjct: 669 ESFLDRSV 676
>NP_077719
          Length = 2471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CQSFVD 6
            C++FVD
Sbjct: 1301 CETFVD 1306
>NP_001159521
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   QSFVDRSL 9
           Q FV RSL
Sbjct: 229 QDFVSRSL 236
>NP_060289
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SFVDRSL 9
           SFVD+S+
Sbjct: 311 SFVDKSM 317
>NP_001106995
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CQSFVD 6
           CQ+F+D
Sbjct: 256 CQAFLD 261
>NP_006837
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   CQSFVDR 7
           CQS  DR
Sbjct: 885 CQSIFDR 891
>NP_689908
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CQSFVD 6
           CQ+F+D
Sbjct: 180 CQNFLD 185
>NP_056169
          Length = 1749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    CQSFVDRSL 9
            CQ  +D+SL
Sbjct: 1573 CQILLDQSL 1581
>NP_659441
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVDRSL 9
           F+DRSL
Sbjct: 156 FIDRSL 161
>XP_006726776
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CQSFVDRSL 9
          C++  DRSL
Sbjct: 8  CRTLSDRSL 16
>XP_006725181
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVDRSL 9
           F+DRSL
Sbjct: 156 FIDRSL 161
>XP_006725180
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVDRSL 9
           F+DRSL
Sbjct: 156 FIDRSL 161
>XP_005258694
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   QSFVDRSL 9
           Q FV RSL
Sbjct: 229 QDFVSRSL 236
>XP_006722987
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SFVDRS 8
           SF+DRS
Sbjct: 316 SFIDRS 321
>XP_006721688
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CQSFVDRSL 9
          C++  DRSL
Sbjct: 8  CRTLSDRSL 16
>XP_006716362
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVDRSL 9
           F+DRSL
Sbjct: 156 FIDRSL 161
>XP_006716361
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVDRSL 9
           F+DRSL
Sbjct: 156 FIDRSL 161
>XP_005247216
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CQSFVD 6
           CQ+F+D
Sbjct: 256 CQAFLD 261
>XP_005270959
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CQSFVD 6
            C++FVD
Sbjct: 1262 CETFVD 1267
>XP_005270958
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CQSFVD 6
            C++FVD
Sbjct: 1262 CETFVD 1267
>XP_006710730
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CQSFVD 6
            C++FVD
Sbjct: 1262 CETFVD 1267
>XP_006710092
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CQSFVDRSL 9
          C++  DRSL
Sbjct: 8  CRTLSDRSL 16
>NP_001121170
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   CQSFVDR 7
           CQS  DR
Sbjct: 885 CQSIFDR 891
>NP_001121171
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   CQSFVDR 7
           CQS  DR
Sbjct: 885 CQSIFDR 891
>NP_060301
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 1   CQSFVDR 7
           CQ ++D+
Sbjct: 119 CQKYIDK 125
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.137    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 531,145
Number of extensions: 1136
Number of successful extensions: 74
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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