Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689716                                                              17    2528
NP_001244960                                                           17    3301
NP_001139669                                                           17    3301
NP_000273                                                              17    4312
NP_001171475                                                           17    4312
XP_005254116                                                           17    4312
NP_001231293                                                           16    5631
NP_001073948                                                           16    5631
NP_001171164                                                           16    5631
XP_006716244                                                           16    5631
XP_005250774                                                           16    5631
XP_005248625                                                           16    5631
XP_006714732                                                           16    5631
NP_004270                                                              16    5631
NP_001035829                                                           16    7355
NP_001166996                                                           16    7355
NP_004591                                                              16    7355
NP_001166995                                                           16    7355
NP_775873                                                              16    7355
NP_001035828                                                           16    7355
NP_065876                                                              16    7355
NP_001013663                                                           16    7355
XP_006719585                                                           16    7355
XP_006719584                                                           16    7355
XP_005269101                                                           16    7355
XP_006719583                                                           16    7355
XP_006711560                                                           16    7355
XP_006711559                                                           16    7355
XP_006711558                                                           16    7355
NP_067047                                                              15    9605
NP_001230675                                                           15    9605
NP_060035                                                              15    9605
NP_055756                                                              15    9605
NP_001118230                                                           15    9605
NP_060587                                                              15    9605
NP_001264214                                                           15    9605
NP_001243183                                                           15    9605
NP_001243181                                                           15    9605
NP_001965                                                              15    9605
NP_001243184                                                           15    9605
XP_005261449                                                           15    9605
XP_005261448                                                           15    9605
XP_006722022                                                           15    9605
XP_006721512                                                           15    9605
XP_006721511                                                           15    9605
XP_006718858                                                           15    9605
XP_005270021                                                           15    9605
XP_005270020                                                           15    9605
XP_005270019                                                           15    9605
XP_006717280                                                           15    9605
XP_006717279                                                           15    9605
XP_006717278                                                           15    9605
XP_006717277                                                           15    9605
XP_006717276                                                           15    9605
XP_006717275                                                           15    9605
XP_006717274                                                           15    9605
XP_006717273                                                           15    9605
XP_006717272                                                           15    9605
NP_062545                                                              15    9605
>NP_689716
          Length = 1052

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    CLIVSRTLL 9
            C+I S+TLL
Sbjct: 1017 CIIASQTLL 1025
>NP_001244960
          Length = 518

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  CLIVSRTLL 9
          CL++SRT++
Sbjct: 76 CLLLSRTVV 84
>NP_001139669
          Length = 7081

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    CLIVSRTLL 9
            C+++SRT L
Sbjct: 5546 CVVLSRTFL 5554
>NP_000273
          Length = 728

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CLIVSRTL 8
          CL+VSR L
Sbjct: 44 CLMVSRNL 51
>NP_001171475
          Length = 681

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CLIVSRTL 8
          CL+VSR L
Sbjct: 44 CLMVSRNL 51
>XP_005254116
          Length = 640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CLIVSRTL 8
          CL+VSR L
Sbjct: 44 CLMVSRNL 51
>NP_001231293
          Length = 1392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           CL+  +TLL
Sbjct: 353 CLVCDKTLL 361
>NP_001073948
          Length = 1731

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           CL+  +TLL
Sbjct: 666 CLVCDKTLL 674
>NP_001171164
          Length = 1705

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           CL+  +TLL
Sbjct: 666 CLVCDKTLL 674
>XP_006716244
          Length = 506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CLIVSRTLL 9
           CL+V+ TL+
Sbjct: 312 CLMVANTLI 320
>XP_005250774
          Length = 508

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CLIVSRTLL 9
           CL+V+ TL+
Sbjct: 312 CLMVANTLI 320
>XP_005248625
          Length = 1418

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           CL+  +TLL
Sbjct: 353 CLVCDKTLL 361
>XP_006714732
          Length = 1633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           CL+  +TLL
Sbjct: 568 CLVCDKTLL 576
>NP_004270
          Length = 489

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CLIVSRTLL 9
           CL+V+ TL+
Sbjct: 312 CLMVANTLI 320
>NP_001035829
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CLIVSRT 7
           C++V+RT
Sbjct: 400 CMVVTRT 406
>NP_001166996
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CLIVSRT 7
           C++V+RT
Sbjct: 400 CMVVTRT 406
>NP_004591
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CLIVSRT 7
           C++V+RT
Sbjct: 400 CMVVTRT 406
>NP_001166995
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CLIVSRT 7
           C++V+RT
Sbjct: 400 CMVVTRT 406
>NP_775873
          Length = 1576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    CLIVSRTLL 9
            C++ S+TL+
Sbjct: 1102 CILTSQTLM 1110
>NP_001035828
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CLIVSRT 7
           C++V+RT
Sbjct: 400 CMVVTRT 406
>NP_065876
          Length = 1269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LIVSRTLL 9
           L+V RTLL
Sbjct: 887 LVVQRTLL 894
>NP_001013663
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           CL+  RTLL
Sbjct: 301 CLVGVRTLL 309
>XP_006719585
          Length = 1459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CLIVSRTLL 9
           C++ S+TL+
Sbjct: 985 CILTSQTLM 993
>XP_006719584
          Length = 1515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    CLIVSRTLL 9
            C++ S+TL+
Sbjct: 1041 CILTSQTLM 1049
>XP_005269101
          Length = 1577

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    CLIVSRTLL 9
            C++ S+TL+
Sbjct: 1103 CILTSQTLM 1111
>XP_006719583
          Length = 1586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    CLIVSRTLL 9
            C++ S+TL+
Sbjct: 1112 CILTSQTLM 1120
>XP_006711560
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CLIVSRT 7
           C++V+RT
Sbjct: 400 CMVVTRT 406
>XP_006711559
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CLIVSRT 7
           C++V+RT
Sbjct: 422 CMVVTRT 428
>XP_006711558
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CLIVSRT 7
           C++V+RT
Sbjct: 422 CMVVTRT 428
>NP_067047
          Length = 2506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>NP_001230675
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           C+I  +TLL
Sbjct: 315 CMIKKKTLL 323
>NP_060035
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           C+I  +TLL
Sbjct: 453 CMIKKKTLL 461
>NP_055756
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  CLIVSRT 7
          CL +SRT
Sbjct: 65 CLFLSRT 71
>NP_001118230
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CLIVSRTLL 9
           C+ V  TLL
Sbjct: 428 CIFVGETLL 436
>NP_060587
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CLIVSR 6
           CL+VSR
Sbjct: 913 CLLVSR 918
>NP_001264214
          Length = 1437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CLIVSRT 7
           CLI +RT
Sbjct: 620 CLIANRT 626
>NP_001243183
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   CLIVSRTL 8
           CL++++TL
Sbjct: 503 CLLLAKTL 510
>NP_001243181
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   CLIVSRTL 8
           CL++++TL
Sbjct: 592 CLLLAKTL 599
>NP_001965
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   CLIVSRTL 8
           CL++++TL
Sbjct: 644 CLLLAKTL 651
>NP_001243184
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   CLIVSRTL 8
           CL++++TL
Sbjct: 467 CLLLAKTL 474
>XP_005261449
          Length = 1029

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CLIVSRT 7
           CL +SRT
Sbjct: 127 CLFLSRT 133
>XP_005261448
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CLIVSRT 7
           CL +SRT
Sbjct: 127 CLFLSRT 133
>XP_006722022
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLIVSRTLL 9
           C+I  +TLL
Sbjct: 315 CMIKKKTLL 323
>XP_006721512
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CLIVSRTLL 9
           C+ V  TLL
Sbjct: 258 CIFVGETLL 266
>XP_006721511
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CLIVSRTLL 9
           C+ V  TLL
Sbjct: 277 CIFVGETLL 285
>XP_006718858
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CLIVSRT 7
           CLI +RT
Sbjct: 96  CLIANRT 102
>XP_005270021
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CLIVSR 6
           CL+VSR
Sbjct: 442 CLLVSR 447
>XP_005270020
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CLIVSR 6
           CL+VSR
Sbjct: 654 CLLVSR 659
>XP_005270019
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CLIVSR 6
           CL+VSR
Sbjct: 654 CLLVSR 659
>XP_006717280
          Length = 2221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717279
          Length = 2506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717278
          Length = 2566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717277
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717276
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717275
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717274
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717273
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>XP_006717272
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CLIVSRTL 8
            CL  SRT+
Sbjct: 1729 CLAASRTI 1736
>NP_062545
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  CLIVSRTLL 9
          CL VSR  L
Sbjct: 50 CLAVSRIFL 58
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.150    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 331,881
Number of extensions: 495
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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