Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              20     299
NP_005893                                                              18    1935
NP_005891                                                              18    1935
NP_001003688                                                           18    1935
NP_001003652                                                           18    1935
NP_001138576                                                           18    1935
NP_001129409                                                           18    1935
NP_001138574                                                           18    1935
NP_005892                                                              18    1935
NP_001138575                                                           18    1935
NP_001001419                                                           18    1935
NP_005894                                                              18    1935
NP_001001420                                                           18    1935
NP_005896                                                              18    1935
NP_001120689                                                           18    1935
XP_006722514                                                           18    1935
XP_005258316                                                           18    1935
XP_006720569                                                           18    1935
XP_005266461                                                           18    1935
XP_005266460                                                           18    1935
XP_005266458                                                           18    1935
XP_006719890                                                           18    1935
XP_005263050                                                           18    1935
XP_005263049                                                           18    1935
XP_005263048                                                           18    1935
XP_006714280                                                           18    1935
NP_665682                                                              16    5631
NP_001188410                                                           16    5631
NP_115912                                                              16    5631
NP_001188411                                                           16    5631
NP_001188409                                                           16    5631
NP_000951                                                              16    5631
XP_005259152                                                           16    5631
XP_005259150                                                           16    5631
XP_006712295                                                           16    5631
XP_006712294                                                           16    5631
NP_001119580                                                           16    7355
NP_000330                                                              16    7355
NP_001119579                                                           16    7355
XP_005256176                                                           16    7355
NP_001007190                                                           16    7355
NP_055223                                                              15    9605
NP_005662                                                              15    9605
NP_001269128                                                           15    9605
NP_001269118                                                           15    9605
NP_001257826                                                           15    9605
NP_001257825                                                           15    9605
NP_001257823                                                           15    9605
NP_001257824                                                           15    9605
XP_006719412                                                           15    9605
NP_068567                                                              15    9605
>NP_005350
          Length = 552

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CILRMRFVK 9
           CILRM FVK
Sbjct: 499 CILRMSFVK 507
>NP_005893
          Length = 425

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 370 CTIRMSFVK 378
>NP_005891
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 410 CTIRMSFVK 418
>NP_001003688
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 410 CTIRMSFVK 418
>NP_001003652
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 412 CTIRMSFVK 420
>NP_001138576
          Length = 230

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 175 CTIRMSFVK 183
>NP_001129409
          Length = 437

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 382 CTIRMSFVK 390
>NP_001138574
          Length = 320

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 265 CTIRMSFVK 273
>NP_005892
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 412 CTIRMSFVK 420
>NP_001138575
          Length = 381

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 326 CTIRMSFVK 334
>NP_001001419
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 410 CTIRMSFVK 418
>NP_005894
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 410 CTIRMSFVK 418
>NP_001001420
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 410 CTIRMSFVK 418
>NP_005896
          Length = 430

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 375 CTIRMSFVK 383
>NP_001120689
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 412 CTIRMSFVK 420
>XP_006722514
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 412 CTIRMSFVK 420
>XP_005258316
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 412 CTIRMSFVK 420
>XP_006720569
          Length = 373

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 318 CTIRMSFVK 326
>XP_005266461
          Length = 356

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 289 CTIRMSFVK 297
>XP_005266460
          Length = 393

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 326 CTIRMSFVK 334
>XP_005266458
          Length = 442

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 375 CTIRMSFVK 383
>XP_006719890
          Length = 479

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 412 CTIRMSFVK 420
>XP_005263050
          Length = 426

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 371 CTIRMSFVK 379
>XP_005263049
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 410 CTIRMSFVK 418
>XP_005263048
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 410 CTIRMSFVK 418
>XP_006714280
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C +RM FVK
Sbjct: 410 CTIRMSFVK 418
>NP_665682
          Length = 938

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           CI ++ FVK
Sbjct: 763 CICKLTFVK 771
>NP_001188410
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           CI ++ FVK
Sbjct: 728 CICKLTFVK 736
>NP_115912
          Length = 934

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           CI ++ FVK
Sbjct: 759 CICKLTFVK 767
>NP_001188411
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           CI ++ FVK
Sbjct: 723 CICKLTFVK 731
>NP_001188409
          Length = 959

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           CI ++ FVK
Sbjct: 784 CICKLTFVK 792
>NP_000951
          Length = 386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C LRMR+ +
Sbjct: 170 CFLRMRWAQ 178
>XP_005259152
          Length = 257

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C LRMR+ +
Sbjct: 170 CFLRMRWAQ 178
>XP_005259150
          Length = 342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           C LRMR+ +
Sbjct: 170 CFLRMRWAQ 178
>XP_006712295
          Length = 923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           CI ++ FVK
Sbjct: 748 CICKLTFVK 756
>XP_006712294
          Length = 928

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CILRMRFVK 9
           CI ++ FVK
Sbjct: 753 CICKLTFVK 761
>NP_001119580
          Length = 1021

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CILRMR 6
           C++RMR
Sbjct: 772 CVMRMR 777
>NP_000330
          Length = 1030

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CILRMR 6
           C++RMR
Sbjct: 772 CVMRMR 777
>NP_001119579
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CILRMR 6
           C++RMR
Sbjct: 771 CVMRMR 776
>XP_005256176
          Length = 1020

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CILRMR 6
           C++RMR
Sbjct: 771 CVMRMR 776
>NP_001007190
          Length = 53

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CILRMRFVK 9
          CI R+ FV+
Sbjct: 42 CISRLEFVQ 50
>NP_055223
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LRMRFVK 9
           +RMRF++
Sbjct: 163 IRMRFIR 169
>NP_005662
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILRMRFVK 9
           +LR RF+K
Sbjct: 203 VLRRRFLK 210
>NP_001269128
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILRMRFVK 9
           +LR RF+K
Sbjct: 162 VLRRRFLK 169
>NP_001269118
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILRMRFVK 9
           +LR RF+K
Sbjct: 166 VLRRRFLK 173
>NP_001257826
          Length = 114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LRMRFVK 9
           +RMRF++
Sbjct: 97  IRMRFIR 103
>NP_001257825
          Length = 134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LRMRFVK 9
           +RMRF++
Sbjct: 117 IRMRFIR 123
>NP_001257823
          Length = 188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LRMRFVK 9
           +RMRF++
Sbjct: 171 IRMRFIR 177
>NP_001257824
          Length = 134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LRMRFVK 9
           +RMRF++
Sbjct: 117 IRMRFIR 123
>XP_006719412
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 7/8 (87%)

Query: 1   CILRMRFV 8
           C++R +F+
Sbjct: 704 CVVRTKFI 711
>NP_068567
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CILRMRFV 8
           C L +RFV
Sbjct: 389 CFLLLRFV 396
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.363    0.160    0.548 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 400,430
Number of extensions: 611
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.3 bits)
S2: 28 (15.4 bits)

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