Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           22     134
NP_001257437                                                           22     134
NP_006281                                                              22     134
XP_006715618                                                           22     134
XP_005267176                                                           22     134
NP_001269557                                                           17    4312
NP_001269560                                                           17    4312
NP_000038                                                              17    4312
XP_005276327                                                           17    4312
XP_005274578                                                           17    4312
XP_005274576                                                           17    4312
XP_005274575                                                           17    4312
XP_006714808                                                           17    4312
XP_006710231                                                           17    4312
NP_001035241                                                           16    5631
NP_060870                                                              16    5631
NP_000377                                                              16    5631
NP_002967                                                              16    5631
NP_001073981                                                           16    5631
XP_006718945                                                           16    5631
XP_005270227                                                           16    5631
XP_005270226                                                           16    5631
XP_005270225                                                           16    5631
XP_005270224                                                           16    5631
XP_005270223                                                           16    5631
XP_006712745                                                           16    5631
XP_006712744                                                           16    5631
XP_006712743                                                           16    5631
NP_695003                                                              16    5631
NP_938009                                                              16    7355
NP_001243000                                                           16    7355
NP_689909                                                              16    7355
XP_005257603                                                           16    7355
XP_006722058                                                           16    7355
XP_005257602                                                           16    7355
XP_005273217                                                           16    7355
XP_005270670                                                           16    7355
XP_005270669                                                           16    7355
XP_006710506                                                           16    7355
XP_005270668                                                           16    7355
XP_005270667                                                           16    7355
XP_005270666                                                           16    7355
NP_055177                                                              15    9605
NP_932164                                                              15    9605
NP_055627                                                              15    9605
NP_001035864                                                           15    9605
NP_001035863                                                           15    9605
NP_057004                                                              15    9605
NP_001092806                                                           15    9605
NP_940923                                                              15    9605
XP_006725047                                                           15    9605
XP_006725046                                                           15    9605
XP_006725045                                                           15    9605
XP_006725044                                                           15    9605
XP_006725043                                                           15    9605
XP_006725042                                                           15    9605
XP_006725041                                                           15    9605
XP_006725040                                                           15    9605
XP_006725039                                                           15    9605
XP_006725038                                                           15    9605
XP_006725037                                                           15    9605
XP_006719444                                                           15    9605
XP_006711915                                                           15    9605
XP_006711914                                                           15    9605
XP_006711913                                                           15    9605
XP_006711912                                                           15    9605
XP_006711911                                                           15    9605
XP_005273418                                                           15    9605
XP_006711910                                                           15    9605
XP_006711909                                                           15    9605
XP_006711908                                                           15    9605
XP_006711907                                                           15    9605
XP_006711906                                                           15    9605
NP_001021                                                              15    9605
>NP_001257436
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CFKRTTVEA 9
           CFKRTT EA
Sbjct: 539 CFKRTTAEA 547
>NP_001257437
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CFKRTTVEA 9
           CFKRTT EA
Sbjct: 539 CFKRTTAEA 547
>NP_006281
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CFKRTTVEA 9
           CFKRTT EA
Sbjct: 539 CFKRTTAEA 547
>XP_006715618
          Length = 577

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CFKRTTVEA 9
           CFKRTT EA
Sbjct: 326 CFKRTTAEA 334
>XP_005267176
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CFKRTTVEA 9
           CFKRTT EA
Sbjct: 539 CFKRTTAEA 547
>NP_001269557
          Length = 614

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CFKRTT 6
           CF+RTT
Sbjct: 292 CFQRTT 297
>NP_001269560
          Length = 544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CFKRTT 6
           CF+RTT
Sbjct: 222 CFQRTT 227
>NP_000038
          Length = 589

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CFKRTT 6
           CF+RTT
Sbjct: 267 CFQRTT 272
>XP_005276327
          Length = 289

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CFKRTTV 7
           CF RTTV
Sbjct: 240 CFCRTTV 246
>XP_005274578
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CFKRTT 6
           CF+RTT
Sbjct: 213 CFQRTT 218
>XP_005274576
          Length = 589

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CFKRTT 6
           CF+RTT
Sbjct: 267 CFQRTT 272
>XP_005274575
          Length = 598

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CFKRTT 6
           CF+RTT
Sbjct: 276 CFQRTT 281
>XP_006714808
          Length = 222

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CFKRTTV 7
           CF RTTV
Sbjct: 127 CFCRTTV 133
>XP_006710231
          Length = 222

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CFKRTTV 7
           CF RTTV
Sbjct: 127 CFCRTTV 133
>NP_001035241
          Length = 215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  CFKRTTVEA 9
          C KR  VEA
Sbjct: 48 CMKREEVEA 56
>NP_060870
          Length = 215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  CFKRTTVEA 9
          C KR  VEA
Sbjct: 48 CMKREEVEA 56
>NP_000377
          Length = 455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  CFKRTTVE 8
          C KR TV+
Sbjct: 40 CLKRATVQ 47
>NP_002967
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C +RTT++
Sbjct: 106 CIRRTTIK 113
>NP_001073981
          Length = 974

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR TVE
Sbjct: 654 CAKRQTVE 661
>XP_006718945
          Length = 215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  CFKRTTVEA 9
          C KR  VEA
Sbjct: 48 CMKREEVEA 56
>XP_005270227
          Length = 909

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR TVE
Sbjct: 589 CAKRQTVE 596
>XP_005270226
          Length = 927

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR TVE
Sbjct: 607 CAKRQTVE 614
>XP_005270225
          Length = 949

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR TVE
Sbjct: 654 CAKRQTVE 661
>XP_005270224
          Length = 949

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR TVE
Sbjct: 654 CAKRQTVE 661
>XP_005270223
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR TVE
Sbjct: 654 CAKRQTVE 661
>XP_006712745
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C +RTT++
Sbjct: 106 CIRRTTIK 113
>XP_006712744
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C +RTT++
Sbjct: 106 CIRRTTIK 113
>XP_006712743
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C +RTT++
Sbjct: 106 CIRRTTIK 113
>NP_695003
          Length = 574

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CFKRTTVEA 9
           CF R+ VEA
Sbjct: 188 CFVRSGVEA 196
>NP_938009
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C+KR+T E
Sbjct: 207 CWKRSTKE 214
>NP_001243000
          Length = 5207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CFKRTTVE 8
            C KR TVE
Sbjct: 4743 CRKRITVE 4750
>NP_689909
          Length = 1075

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C+KR+T E
Sbjct: 207 CWKRSTKE 214
>XP_005257603
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CFKRTTVE 8
            C KR TVE
Sbjct: 4792 CRKRITVE 4799
>XP_006722058
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CFKRTTVE 8
            C KR TVE
Sbjct: 4792 CRKRITVE 4799
>XP_005257602
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    CFKRTTVE 8
            C KR TVE
Sbjct: 4792 CRKRITVE 4799
>XP_005273217
          Length = 1141

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CFKRTTV 7
            CF +TTV
Sbjct: 1133 CFPQTTV 1139
>XP_005270670
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C+KR+T E
Sbjct: 207 CWKRSTKE 214
>XP_005270669
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C+KR+T E
Sbjct: 207 CWKRSTKE 214
>XP_006710506
          Length = 1247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C+KR+T E
Sbjct: 278 CWKRSTKE 285
>XP_005270668
          Length = 1256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C+KR+T E
Sbjct: 278 CWKRSTKE 285
>XP_005270667
          Length = 1280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C+KR+T E
Sbjct: 278 CWKRSTKE 285
>XP_005270666
          Length = 1281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CFKRTTVE 8
           C+KR+T E
Sbjct: 278 CWKRSTKE 285
>NP_055177
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   CFKRTTVE 8
           CF   TVE
Sbjct: 271 CFSANTVE 278
>NP_932164
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   CFKRTTVE 8
           CF   TVE
Sbjct: 271 CFSANTVE 278
>NP_055627
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>NP_001035864
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>NP_001035863
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>NP_057004
          Length = 84

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  CFKRTTV 7
          C+K TTV
Sbjct: 40 CYKITTV 46
>NP_001092806
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  CFKRTTV 7
          C++RT+V
Sbjct: 53 CYERTSV 59
>NP_940923
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  CFKRTTV 7
          C++RT+V
Sbjct: 53 CYERTSV 59
>XP_006725047
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725046
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725045
          Length = 1496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725044
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725043
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725042
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725041
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725040
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725039
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725038
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006725037
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006719444
          Length = 236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  CFKRTTV 7
          C++RT+V
Sbjct: 53 CYERTSV 59
>XP_006711915
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711914
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711913
          Length = 1496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711912
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711911
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_005273418
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711910
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711909
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711908
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711907
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>XP_006711906
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFKRTTVE 8
           C KR T+E
Sbjct: 390 CSKRATLE 397
>NP_001021
          Length = 84

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  CFKRTTV 7
          C+K TTV
Sbjct: 40 CYKITTV 46
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.130    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 402,296
Number of extensions: 506
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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