Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1135
NP_001075109                                                           18    1135
NP_001106853                                                           17    2528
XP_006712889                                                           17    2528
NP_055627                                                              17    3301
NP_001035864                                                           17    3301
NP_001035863                                                           17    3301
NP_001106197                                                           17    3301
XP_006725047                                                           17    3301
XP_006725046                                                           17    3301
XP_006725045                                                           17    3301
XP_006725044                                                           17    3301
XP_006725043                                                           17    3301
XP_006725042                                                           17    3301
XP_006725041                                                           17    3301
XP_006725040                                                           17    3301
XP_006725039                                                           17    3301
XP_006725038                                                           17    3301
XP_006725037                                                           17    3301
XP_005267607                                                           17    3301
XP_006711915                                                           17    3301
XP_006711914                                                           17    3301
XP_006711913                                                           17    3301
XP_006711912                                                           17    3301
XP_006711911                                                           17    3301
XP_005273418                                                           17    3301
XP_006711910                                                           17    3301
XP_006711909                                                           17    3301
XP_006711908                                                           17    3301
XP_006711907                                                           17    3301
XP_006711906                                                           17    3301
NP_057147                                                              17    4312
NP_001276                                                              16    5631
NP_000050                                                              16    7355
NP_036561                                                              16    7355
NP_203740                                                              16    7355
NP_775733                                                              16    7355
XP_005268242                                                           16    7355
XP_005268241                                                           16    7355
NP_037368                                                              15    9605
NP_001161093                                                           15    9605
NP_115627                                                              15    9605
NP_009029                                                              15    9605
NP_001826                                                              15    9605
XP_006724391                                                           15    9605
XP_005261338                                                           15    9605
XP_005277858                                                           15    9605
XP_006724390                                                           15    9605
XP_006724389                                                           15    9605
XP_005277857                                                           15    9605
XP_006718583                                                           15    9605
XP_006718582                                                           15    9605
NP_005870                                                              15    9605
>NP_008835
          Length = 4128

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ELILQSTR 9
           ELILQSTR
Sbjct: 652 ELILQSTR 659
>NP_001075109
          Length = 4097

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ELILQSTR 9
           ELILQSTR
Sbjct: 652 ELILQSTR 659
>NP_001106853
          Length = 2093

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    CELILQSTR 9
            CELILQ+ +
Sbjct: 1232 CELILQTEK 1240
>XP_006712889
          Length = 2069

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    CELILQSTR 9
            CELILQ+ +
Sbjct: 1217 CELILQTEK 1225
>NP_055627
          Length = 1584

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>NP_001035864
          Length = 1460

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>NP_001035863
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>NP_001106197
          Length = 1554

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725047
          Length = 1460

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725046
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725045
          Length = 1496

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725044
          Length = 1584

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725043
          Length = 1593

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725042
          Length = 1594

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725041
          Length = 1610

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725040
          Length = 1620

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725039
          Length = 1629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725038
          Length = 1646

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006725037
          Length = 1656

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_005267607
          Length = 1589

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711915
          Length = 1460

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711914
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711913
          Length = 1496

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711912
          Length = 1584

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711911
          Length = 1593

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_005273418
          Length = 1594

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711910
          Length = 1610

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711909
          Length = 1620

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711908
          Length = 1629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711907
          Length = 1646

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>XP_006711906
          Length = 1656

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CELILQS 7
          CEL+LQS
Sbjct: 30 CELMLQS 36
>NP_057147
          Length = 204

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   CELILQST 8
           CE+ILQ++
Sbjct: 145 CEMILQAS 152
>NP_001276
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CELILQS 7
           CE +LQS
Sbjct: 223 CEFVLQS 229
>NP_000050
          Length = 3418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CELILQS 7
            C+LILQ+
Sbjct: 1290 CQLILQN 1296
>NP_036561
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CELILQ 6
           CEL+LQ
Sbjct: 128 CELLLQ 133
>NP_203740
          Length = 392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CELILQ 6
           CEL+LQ
Sbjct: 128 CELLLQ 133
>NP_775733
          Length = 1251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CELILQS 7
            C+LILQ+
Sbjct: 1217 CDLILQA 1223
>XP_005268242
          Length = 1285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CELILQS 7
            C+LILQ+
Sbjct: 1251 CDLILQA 1257
>XP_005268241
          Length = 1300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    CELILQS 7
            C+LILQ+
Sbjct: 1266 CDLILQA 1272
>NP_037368
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ELILQSTR 9
           +LIL+STR
Sbjct: 463 KLILKSTR 470
>NP_001161093
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ELILQSTR 9
           +LIL+STR
Sbjct: 399 KLILKSTR 406
>NP_115627
          Length = 1476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELILQSTR 9
            EL+LQS R
Sbjct: 1017 ELLLQSQR 1024
>NP_009029
          Length = 1640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CELILQSTR 9
           C L+LQ  R
Sbjct: 436 CHLVLQQGR 444
>NP_001826
          Length = 1583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CELILQSTR 9
           C L+LQ  R
Sbjct: 436 CHLVLQQGR 444
>XP_006724391
          Length = 1567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CELILQSTR 9
           C L+LQ  R
Sbjct: 457 CHLVLQQGR 465
>XP_005261338
          Length = 1570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CELILQSTR 9
           C L+LQ  R
Sbjct: 457 CHLVLQQGR 465
>XP_005277858
          Length = 1604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CELILQSTR 9
           C L+LQ  R
Sbjct: 457 CHLVLQQGR 465
>XP_006724390
          Length = 1623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CELILQSTR 9
           C L+LQ  R
Sbjct: 419 CHLVLQQGR 427
>XP_006724389
          Length = 1653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CELILQSTR 9
           C L+LQ  R
Sbjct: 457 CHLVLQQGR 465
>XP_005277857
          Length = 1661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CELILQSTR 9
           C L+LQ  R
Sbjct: 457 CHLVLQQGR 465
>XP_006718583
          Length = 1482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ELILQSTR 9
           EL+LQS R
Sbjct: 939 ELLLQSQR 946
>XP_006718582
          Length = 1560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELILQSTR 9
            EL+LQS R
Sbjct: 1017 ELLLQSQR 1024
>NP_005870
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ELILQSTR 9
           EL+LQS R
Sbjct: 170 ELLLQSQR 177
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 434,853
Number of extensions: 581
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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