Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              21     229
XP_005262424                                                           21     229
NP_001139566                                                           16    5631
NP_055782                                                              16    5631
NP_001139568                                                           16    5631
NP_001139567                                                           16    5631
NP_001032961                                                           16    5631
NP_057400                                                              16    5631
XP_006725604                                                           16    5631
XP_006725603                                                           16    5631
XP_006725602                                                           16    5631
XP_006725601                                                           16    5631
XP_006725600                                                           16    5631
XP_005254293                                                           16    5631
XP_005254289                                                           16    5631
XP_005254292                                                           16    5631
XP_005254291                                                           16    5631
XP_005254290                                                           16    5631
XP_006712656                                                           16    5631
XP_005264025                                                           16    5631
XP_006712655                                                           16    5631
NP_061992                                                              16    7355
NP_001005476                                                           16    7355
NP_003619                                                              16    7355
NP_003961                                                              15    9605
NP_001157790                                                           15    9605
NP_057332                                                              15    9605
NP_003310                                                              15    9605
NP_001157791                                                           15    9605
NP_597676                                                              15    9605
NP_596870                                                              15    9605
NP_001157789                                                           15    9605
NP_001243779                                                           15    9605
NP_001448                                                              15    9605
NP_596869                                                              15    9605
NP_001240841                                                           15    9605
NP_055988                                                              15    9605
NP_003861                                                              15    9605
NP_001271175                                                           15    9605
NP_056371                                                              15    9605
NP_001271176                                                           15    9605
NP_001271174                                                           15    9605
NP_001077086                                                           15    9605
NP_055596                                                              15    9605
XP_005267576                                                           15    9605
XP_006720175                                                           15    9605
XP_006720174                                                           15    9605
XP_005267573                                                           15    9605
XP_006720173                                                           15    9605
XP_006720172                                                           15    9605
XP_005267571                                                           15    9605
XP_005266307                                                           15    9605
XP_005266306                                                           15    9605
XP_005266305                                                           15    9605
XP_005266304                                                           15    9605
XP_006716556                                                           15    9605
XP_006716555                                                           15    9605
XP_006716554                                                           15    9605
XP_006716300                                                           15    9605
XP_005262708                                                           15    9605
XP_005262706                                                           15    9605
XP_006714063                                                           15    9605
XP_005262705                                                           15    9605
XP_006714062                                                           15    9605
XP_005262704                                                           15    9605
XP_005262703                                                           15    9605
XP_006713130                                                           15    9605
XP_005265035                                                           15    9605
XP_005265034                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
NP_839943                                                              15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605
>NP_722576
          Length = 3080

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    CDEISMTLT 9
            CDEISM LT
Sbjct: 2503 CDEISMNLT 2511
>XP_005262424
          Length = 2875

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    CDEISMTLT 9
            CDEISM LT
Sbjct: 2298 CDEISMNLT 2306
>NP_001139566
          Length = 533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>NP_055782
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>NP_001139568
          Length = 533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>NP_001139567
          Length = 533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>NP_001032961
          Length = 1250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CDEISMTLT 9
           CD I+ T+T
Sbjct: 776 CDNIARTVT 784
>NP_057400
          Length = 1251

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CDEISMTLT 9
           CD I+ T+T
Sbjct: 777 CDNIARTVT 785
>XP_006725604
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_006725603
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_006725602
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_006725601
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_006725600
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_005254293
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_005254289
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_005254292
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_005254291
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_005254290
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CDEISMTL 8
           C+E+ MT+
Sbjct: 301 CEEVKMTV 308
>XP_006712656
          Length = 761

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CDEISMTLT 9
           CD I+ T+T
Sbjct: 287 CDNIARTVT 295
>XP_005264025
          Length = 1181

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CDEISMTLT 9
           CD I+ T+T
Sbjct: 707 CDNIARTVT 715
>XP_006712655
          Length = 1251

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CDEISMTLT 9
           CD I+ T+T
Sbjct: 777 CDNIARTVT 785
>NP_061992
          Length = 797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DEISMTLT 9
           +E+S+TLT
Sbjct: 206 EELSLTLT 213
>NP_001005476
          Length = 1149

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           CD + MT+
Sbjct: 645 CDAVKMTI 652
>NP_003619
          Length = 1192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           CD + MT+
Sbjct: 645 CDAVKMTI 652
>NP_003961
          Length = 1465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           CD  SMTL
Sbjct: 722 CDGHSMTL 729
>NP_001157790
          Length = 2591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CDEISM 6
            C+E+SM
Sbjct: 2545 CEEVSM 2550
>NP_057332
          Length = 1901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CDEISMTLT 9
           CD  S T+T
Sbjct: 216 CDAASQTVT 224
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2912 DQVSATLT 2919
>NP_001157791
          Length = 2578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CDEISM 6
            C+E+SM
Sbjct: 2532 CEEVSM 2537
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2912 DQVSATLT 2919
>NP_596870
          Length = 5604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2958 DQVSATLT 2965
>NP_001157789
          Length = 2633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CDEISM 6
            C+E+SM
Sbjct: 2587 CEEVSM 2592
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2958 DQVSATLT 2965
>NP_001448
          Length = 2602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CDEISM 6
            C+E+SM
Sbjct: 2556 CEEVSM 2561
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2958 DQVSATLT 2965
>NP_001240841
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 361 DEIMMTL 367
>NP_055988
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 361 DEIMMTL 367
>NP_003861
          Length = 1657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    EISMTLT 9
            E+S+TLT
Sbjct: 1360 EVSLTLT 1366
>NP_001271175
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>NP_056371
          Length = 1804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>NP_001271176
          Length = 1803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>NP_001271174
          Length = 1783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>NP_001077086
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DEISMTLT 9
           DE+S T+T
Sbjct: 626 DEMSQTIT 633
>NP_055596
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DEISMTLT 9
           DE+S T+T
Sbjct: 626 DEMSQTIT 633
>XP_005267576
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>XP_006720175
          Length = 1783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>XP_006720174
          Length = 1803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>XP_005267573
          Length = 1804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>XP_006720173
          Length = 1804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>XP_006720172
          Length = 1804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>XP_005267571
          Length = 1804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           C+ + MTL
Sbjct: 949 CESVEMTL 956
>XP_005266307
          Length = 1796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CDEISMTLT 9
           CD  S T+T
Sbjct: 216 CDAASQTVT 224
>XP_005266306
          Length = 1824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CDEISMTLT 9
           CD  S T+T
Sbjct: 216 CDAASQTVT 224
>XP_005266305
          Length = 1856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CDEISMTLT 9
           CD  S T+T
Sbjct: 171 CDAASQTVT 179
>XP_005266304
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CDEISMTLT 9
           CD  S T+T
Sbjct: 216 CDAASQTVT 224
>XP_006716556
          Length = 1048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DEISMTLT 9
          DE+S T+T
Sbjct: 83 DEMSQTIT 90
>XP_006716555
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DEISMTLT 9
           DE+S T+T
Sbjct: 574 DEMSQTIT 581
>XP_006716554
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DEISMTLT 9
           DE+S T+T
Sbjct: 626 DEMSQTIT 633
>XP_006716300
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CDEISMTL 8
           CD  SMTL
Sbjct: 722 CDGHSMTL 729
>XP_005262708
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 232 DEIMMTL 238
>XP_005262706
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 232 DEIMMTL 238
>XP_006714063
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 361 DEIMMTL 367
>XP_005262705
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 361 DEIMMTL 367
>XP_006714062
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 361 DEIMMTL 367
>XP_005262704
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 361 DEIMMTL 367
>XP_005262703
          Length = 1275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DEISMTL 8
           DEI MTL
Sbjct: 361 DEIMMTL 367
>XP_006713130
          Length = 2109

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CDEISM 6
            C+E+SM
Sbjct: 2063 CEEVSM 2068
>XP_005265035
          Length = 2609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CDEISM 6
            C+E+SM
Sbjct: 2563 CEEVSM 2568
>XP_005265034
          Length = 2622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CDEISM 6
            C+E+SM
Sbjct: 2576 CEEVSM 2581
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2959 DQVSATLT 2966
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2959 DQVSATLT 2966
>NP_839943
          Length = 1631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    EISMTLT 9
            E+S+TLT
Sbjct: 1341 EVSLTLT 1347
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2958 DQVSATLT 2965
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DEISMTLT 9
            D++S TLT
Sbjct: 2912 DQVSATLT 2919
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.127    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 413,320
Number of extensions: 695
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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