Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              20     390
NP_444254                                                              20     390
NP_444253                                                              20     390
NP_444255                                                              20     390
XP_005247551                                                           20     390
XP_005247550                                                           20     390
XP_006713712                                                           20     390
XP_005247549                                                           20     390
NP_001001669                                                           17    3301
NP_997254                                                              17    3301
XP_005252508                                                           17    3301
XP_006717511                                                           17    3301
XP_005252507                                                           17    3301
XP_006714848                                                           17    3301
XP_005268504                                                           17    3301
XP_006714847                                                           17    3301
XP_006718479                                                           17    4312
XP_006718474                                                           17    4312
NP_149037                                                              16    5631
NP_001171700                                                           16    5631
NP_060422                                                              16    5631
NP_054733                                                              16    7355
NP_079255                                                              16    7355
NP_006076                                                              16    7355
NP_001273079                                                           16    7355
NP_114120                                                              16    7355
NP_001106203                                                           16    7355
XP_005268181                                                           16    7355
XP_006720336                                                           16    7355
XP_006720335                                                           16    7355
XP_005268373                                                           16    7355
XP_005268372                                                           16    7355
XP_005268371                                                           16    7355
XP_005268369                                                           16    7355
XP_006720029                                                           16    7355
XP_005268367                                                           16    7355
XP_005268366                                                           16    7355
XP_005268365                                                           16    7355
XP_005268364                                                           16    7355
XP_005273062                                                           16    7355
XP_005273061                                                           16    7355
XP_006711177                                                           16    7355
XP_005273057                                                           16    7355
XP_005273056                                                           16    7355
XP_005273055                                                           16    7355
NP_001074003                                                           15    9605
NP_055677                                                              15    9605
NP_982288                                                              15    9605
XP_005254452                                                           15    9605
XP_005254451                                                           15    9605
XP_005246497                                                           15    9605
NP_001243055                                                           15    9605
>NP_444256
          Length = 1794

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    CASDIQSSS 9
            CASDI+SSS
Sbjct: 1270 CASDIRSSS 1278
>NP_444254
          Length = 1845

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    CASDIQSSS 9
            CASDI+SSS
Sbjct: 1270 CASDIRSSS 1278
>NP_444253
          Length = 1914

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    CASDIQSSS 9
            CASDI+SSS
Sbjct: 1339 CASDIRSSS 1347
>NP_444255
          Length = 1863

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    CASDIQSSS 9
            CASDI+SSS
Sbjct: 1339 CASDIRSSS 1347
>XP_005247551
          Length = 1855

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    CASDIQSSS 9
            CASDI+SSS
Sbjct: 1280 CASDIRSSS 1288
>XP_005247550
          Length = 1856

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    CASDIQSSS 9
            CASDI+SSS
Sbjct: 1349 CASDIRSSS 1357
>XP_006713712
          Length = 1923

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    CASDIQSSS 9
            CASDI+SSS
Sbjct: 1349 CASDIRSSS 1357
>XP_005247549
          Length = 1924

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    CASDIQSSS 9
            CASDI+SSS
Sbjct: 1349 CASDIRSSS 1357
>NP_001001669
          Length = 675

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CASDIQS 7
          CASDI+S
Sbjct: 52 CASDIRS 58
>NP_997254
          Length = 908

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CASDIQSSS 9
           C+SD +SSS
Sbjct: 379 CSSDSESSS 387
>XP_005252508
          Length = 908

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CASDIQSSS 9
           C+SD +SSS
Sbjct: 379 CSSDSESSS 387
>XP_006717511
          Length = 908

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CASDIQSSS 9
           C+SD +SSS
Sbjct: 379 CSSDSESSS 387
>XP_005252507
          Length = 908

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CASDIQSSS 9
           C+SD +SSS
Sbjct: 379 CSSDSESSS 387
>XP_006714848
          Length = 638

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CASDIQS 7
          CASDI+S
Sbjct: 52 CASDIRS 58
>XP_005268504
          Length = 675

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CASDIQS 7
          CASDI+S
Sbjct: 52 CASDIRS 58
>XP_006714847
          Length = 675

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  CASDIQS 7
          CASDI+S
Sbjct: 52 CASDIRS 58
>XP_006718479
          Length = 414

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CASDIQSSS 9
           C+S IQS+S
Sbjct: 96  CSSPIQSAS 104
>XP_006718474
          Length = 897

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   CASDIQSSS 9
           C+S IQS+S
Sbjct: 96  CSSPIQSAS 104
>NP_149037
          Length = 301

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          C++DI+S S
Sbjct: 27 CSTDIESPS 35
>NP_001171700
          Length = 301

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          C++DI+S S
Sbjct: 27 CSTDIESPS 35
>NP_060422
          Length = 689

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   CASDIQSS 8
           CA+DI+S+
Sbjct: 551 CAADIKSA 558
>NP_054733
          Length = 2136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CASDIQ 6
            CA+DIQ
Sbjct: 1580 CAADIQ 1585
>NP_079255
          Length = 1123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CASDIQ 6
          CA+DIQ
Sbjct: 36 CAADIQ 41
>NP_006076
          Length = 308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          CA+D+Q+ +
Sbjct: 42 CATDLQTKA 50
>NP_001273079
          Length = 272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          CA+D+Q+ +
Sbjct: 42 CATDLQTKA 50
>NP_114120
          Length = 645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CASDIQSSS 9
           C SD+Q S+
Sbjct: 94  CNSDLQDSA 102
>NP_001106203
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CASDIQ 6
          CA+DIQ
Sbjct: 38 CAADIQ 43
>XP_005268181
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CASDIQSSS 9
           C SD+Q S+
Sbjct: 94  CNSDLQDSA 102
>XP_006720336
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CASDIQSSS 9
           C SD+Q S+
Sbjct: 94  CNSDLQDSA 102
>XP_006720335
          Length = 645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CASDIQSSS 9
           C SD+Q S+
Sbjct: 94  CNSDLQDSA 102
>XP_005268373
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CASDIQ 6
          CA+DIQ
Sbjct: 36 CAADIQ 41
>XP_005268372
          Length = 1043

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CASDIQ 6
           CA+DIQ
Sbjct: 95  CAADIQ 100
>XP_005268371
          Length = 1067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CASDIQ 6
          CA+DIQ
Sbjct: 42 CAADIQ 47
>XP_005268369
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CASDIQ 6
          CA+DIQ
Sbjct: 20 CAADIQ 25
>XP_006720029
          Length = 1150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CASDIQ 6
          CA+DIQ
Sbjct: 38 CAADIQ 43
>XP_005268367
          Length = 1154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CASDIQ 6
          CA+DIQ
Sbjct: 42 CAADIQ 47
>XP_005268366
          Length = 1180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CASDIQ 6
          CA+DIQ
Sbjct: 68 CAADIQ 73
>XP_005268365
          Length = 1182

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CASDIQ 6
           CA+DIQ
Sbjct: 95  CAADIQ 100
>XP_005268364
          Length = 1207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CASDIQ 6
           CA+DIQ
Sbjct: 95  CAADIQ 100
>XP_005273062
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          CA+D+Q+ +
Sbjct: 42 CATDLQTKA 50
>XP_005273061
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          CA+D+Q+ +
Sbjct: 42 CATDLQTKA 50
>XP_006711177
          Length = 287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          CA+D+Q+ +
Sbjct: 42 CATDLQTKA 50
>XP_005273057
          Length = 308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          CA+D+Q+ +
Sbjct: 42 CATDLQTKA 50
>XP_005273056
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          CA+D+Q+ +
Sbjct: 42 CATDLQTKA 50
>XP_005273055
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CASDIQSSS 9
          CA+D+Q+ +
Sbjct: 42 CATDLQTKA 50
>NP_001074003
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CASDIQSSS 9
           C SD+Q  S
Sbjct: 701 CHSDLQDDS 709
>NP_055677
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SDIQSSS 9
           +DIQSSS
Sbjct: 548 NDIQSSS 554
>NP_982288
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SDIQSSS 9
           SDI+SSS
Sbjct: 341 SDIESSS 347
>XP_005254452
          Length = 2188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CASDIQSSS 9
           C SD+Q  S
Sbjct: 701 CHSDLQDDS 709
>XP_005254451
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CASDIQSSS 9
           C SD+Q  S
Sbjct: 701 CHSDLQDDS 709
>XP_005246497
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SDIQSSS 9
           SDI+SSS
Sbjct: 157 SDIESSS 163
>NP_001243055
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SDIQSSS 9
           SDI+SSS
Sbjct: 349 SDIESSS 355
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.104    0.273 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 451,078
Number of extensions: 1094
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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