Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              20     390
XP_005251512                                                           20     390
NP_001767                                                              17    3301
NP_001157651                                                           17    3301
NP_001157650                                                           17    3301
NP_001091645                                                           17    3301
XP_006718140                                                           17    3301
XP_006718139                                                           17    3301
NP_055524                                                              17    4312
XP_006715083                                                           17    4312
NP_056120                                                              16    5631
NP_055978                                                              16    5631
NP_443210                                                              16    5631
NP_872328                                                              16    5631
NP_689585                                                              16    5631
NP_002218                                                              16    5631
NP_001273648                                                           16    5631
NP_057225                                                              16    5631
NP_057117                                                              16    5631
NP_001005527                                                           16    5631
XP_005267359                                                           16    5631
XP_005267358                                                           16    5631
XP_006720081                                                           16    5631
XP_006720080                                                           16    5631
XP_006716637                                                           16    5631
XP_005251005                                                           16    5631
XP_006716636                                                           16    5631
XP_005251004                                                           16    5631
XP_005251002                                                           16    5631
XP_005251001                                                           16    5631
XP_005270898                                                           16    5631
XP_006710687                                                           16    5631
NP_060909                                                              16    5631
NP_115717                                                              16    7355
NP_057613                                                              16    7355
NP_003322                                                              16    7355
NP_055954                                                              16    7355
NP_003326                                                              16    7355
XP_006719899                                                           16    7355
XP_006719898                                                           16    7355
XP_006719897                                                           16    7355
XP_006719896                                                           16    7355
XP_006719895                                                           16    7355
XP_005266476                                                           16    7355
XP_005265487                                                           16    7355
XP_006713384                                                           16    7355
XP_006710543                                                           16    7355
XP_006710542                                                           16    7355
XP_006710541                                                           16    7355
NP_001001711                                                           16    7355
NP_940857                                                              16    7355
NP_940980                                                              15    9605
NP_002379                                                              15    9605
NP_001257401                                                           15    9605
NP_036606                                                              15    9605
NP_003261                                                              15    9605
NP_001186788                                                           15    9605
NP_001099001                                                           15    9605
NP_079114                                                              15    9605
NP_079040                                                              15    9605
NP_065870                                                              15    9605
NP_001156001                                                           15    9605
XP_005268686                                                           15    9605
XP_005252654                                                           15    9605
XP_005248808                                                           15    9605
XP_005248807                                                           15    9605
XP_005248806                                                           15    9605
XP_005248805                                                           15    9605
XP_005248804                                                           15    9605
XP_005248803                                                           15    9605
XP_005248802                                                           15    9605
XP_005248801                                                           15    9605
XP_005248800                                                           15    9605
>NP_004963
          Length = 1132

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   CAKNILLI 8
           CAKNILLI
Sbjct: 675 CAKNILLI 682
>XP_005251512
          Length = 1132

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   CAKNILLI 8
           CAKNILLI
Sbjct: 675 CAKNILLI 682
>NP_001767
          Length = 510

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CAKNILLI 8
          C+KNIL I
Sbjct: 13 CSKNILAI 20
>NP_001157651
          Length = 469

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CAKNILLI 8
          C+KNIL I
Sbjct: 13 CSKNILAI 20
>NP_001157650
          Length = 522

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CAKNILLI 8
          C+KNIL I
Sbjct: 25 CSKNILAI 32
>NP_001091645
          Length = 517

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CAKNILLI 8
          C+KNIL I
Sbjct: 20 CSKNILAI 27
>XP_006718140
          Length = 474

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CAKNILLI 8
          C+KNIL I
Sbjct: 25 CSKNILAI 32
>XP_006718139
          Length = 482

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  CAKNILLI 8
          C+KNIL I
Sbjct: 25 CSKNILAI 32
>NP_055524
          Length = 3546

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    CAKNILLIG 9
            C +NI LIG
Sbjct: 3095 CRENIKLIG 3103
>XP_006715083
          Length = 764

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CAKNILLIG 9
           C K++++IG
Sbjct: 322 CKKSVIIIG 330
>NP_056120
          Length = 670

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  CAKNILL 7
          C KN+LL
Sbjct: 27 CRKNVLL 33
>NP_055978
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>NP_443210
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>NP_872328
          Length = 140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CAK++LL
Sbjct: 9  CAKSVLL 15
>NP_689585
          Length = 1437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CAKNILLIG 9
           C KN ++IG
Sbjct: 711 CGKNEMVIG 719
>NP_002218
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KN+LL
Sbjct: 716 CTKNLLL 722
>NP_001273648
          Length = 284

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AKNILLIG 9
           +KN+LL+G
Sbjct: 230 SKNLLLLG 237
>NP_057225
          Length = 523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KNILLIG 9
          KN+LL+G
Sbjct: 68 KNVLLLG 74
>NP_057117
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AKNILLIG 9
           +KN+LL+G
Sbjct: 260 SKNLLLLG 267
>NP_001005527
          Length = 140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CAK++LL
Sbjct: 9  CAKSVLL 15
>XP_005267359
          Length = 714

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>XP_005267358
          Length = 777

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>XP_006720081
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>XP_006720080
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>XP_006716637
          Length = 305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AKNILLIG 9
           +KN+LL+G
Sbjct: 260 SKNLLLLG 267
>XP_005251005
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AKNILLIG 9
           +KN+LL+G
Sbjct: 216 SKNLLLLG 223
>XP_006716636
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AKNILLIG 9
           +KN+LL+G
Sbjct: 216 SKNLLLLG 223
>XP_005251004
          Length = 353

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AKNILLIG 9
           +KN+LL+G
Sbjct: 230 SKNLLLLG 237
>XP_005251002
          Length = 372

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AKNILLIG 9
           +KN+LL+G
Sbjct: 260 SKNLLLLG 267
>XP_005251001
          Length = 383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AKNILLIG 9
           +KN+LL+G
Sbjct: 260 SKNLLLLG 267
>XP_005270898
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KN+LL
Sbjct: 716 CTKNLLL 722
>XP_006710687
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KN+LL
Sbjct: 716 CTKNLLL 722
>NP_060909
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   CAKNILL 7
           CA+NIL+
Sbjct: 284 CARNILV 290
>NP_115717
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+L+IG
Sbjct: 338 KNVLVIG 344
>NP_057613
          Length = 1188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+LL+G
Sbjct: 669 KNLLLLG 675
>NP_003322
          Length = 1187

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C +NILL
Sbjct: 736 CGRNILL 742
>NP_055954
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KNIL+
Sbjct: 290 CIKNILI 296
>NP_003326
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  AKNILLIG 9
          AKN++L+G
Sbjct: 48 AKNLVLMG 55
>XP_006719899
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719898
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719897
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719896
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+LL+G
Sbjct: 486 KNLLLLG 492
>XP_006719895
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+LL+G
Sbjct: 563 KNLLLLG 569
>XP_005266476
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_005265487
          Length = 987

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  AKNILLIG 9
          AKN++L+G
Sbjct: 48 AKNLVLMG 55
>XP_006713384
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  AKNILLIG 9
          AKN++L+G
Sbjct: 48 AKNLVLMG 55
>XP_006710543
          Length = 256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KNIL+
Sbjct: 191 CIKNILI 197
>XP_006710542
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KNIL+
Sbjct: 294 CIKNILI 300
>XP_006710541
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KNIL+
Sbjct: 317 CIKNILI 323
>NP_001001711
          Length = 396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLIG 9
           KN+L+IG
Sbjct: 346 KNVLVIG 352
>NP_940857
          Length = 5147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    CAKNILL 7
            CA+N+L+
Sbjct: 2425 CARNLLM 2431
>NP_940980
          Length = 2527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    KNILLIG 9
            KN LL+G
Sbjct: 2260 KNFLLVG 2266
>NP_002379
          Length = 853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NILLIG 9
           NILLIG
Sbjct: 385 NILLIG 390
>NP_001257401
          Length = 818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NILLIG 9
           NILLIG
Sbjct: 350 NILLIG 355
>NP_036606
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CAKNILLIG 9
          CAK + L+G
Sbjct: 37 CAKIVQLLG 45
>NP_003261
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CAKNILLI 8
          C K++LLI
Sbjct: 16 CFKSVLLI 23
>NP_001186788
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CAKNILLIG 9
           C K +LL G
Sbjct: 265 CTKEVLLKG 273
>NP_001099001
          Length = 1319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1219 KNVVLVG 1225
>NP_079114
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KNILLIG 9
          KNI+L+G
Sbjct: 56 KNIILMG 62
>NP_079040
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CAKNILLIG 9
           CA ++ L+G
Sbjct: 189 CANDVALLG 197
>NP_065870
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1202 KNVVLVG 1208
>NP_001156001
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1415 KNVVLVG 1421
>XP_005268686
          Length = 2521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    KNILLIG 9
            KN LL+G
Sbjct: 2260 KNFLLVG 2266
>XP_005252654
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KNILLIG 9
          KNI+L+G
Sbjct: 56 KNIILMG 62
>XP_005248808
          Length = 1121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1021 KNVVLVG 1027
>XP_005248807
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1082 KNVVLVG 1088
>XP_005248806
          Length = 1317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1217 KNVVLVG 1223
>XP_005248805
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1245 KNVVLVG 1251
>XP_005248804
          Length = 1378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1278 KNVVLVG 1284
>XP_005248803
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1355 KNVVLVG 1361
>XP_005248802
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1415 KNVVLVG 1421
>XP_005248801
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1441 KNVVLVG 1447
>XP_005248800
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KNILLIG 9
            KN++L+G
Sbjct: 1441 KNVVLVG 1447
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.152    0.479 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 480,731
Number of extensions: 927
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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