Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              20     299
XP_005251512                                                           20     299
NP_002218                                                              17    2528
XP_005270898                                                           17    2528
XP_006710687                                                           17    2528
NP_003322                                                              17    3301
NP_001230175                                                           17    4312
NP_036466                                                              17    4312
NP_001001976                                                           17    4312
NP_001275663                                                           17    4312
NP_001275664                                                           17    4312
NP_001275665                                                           17    4312
NP_008972                                                              17    4312
NP_071751                                                              17    4312
NP_001139761                                                           17    4312
XP_005258838                                                           17    4312
XP_005269518                                                           17    4312
XP_005269517                                                           17    4312
XP_005269516                                                           17    4312
XP_005269515                                                           17    4312
XP_005269513                                                           17    4312
XP_006714538                                                           17    4312
NP_775904                                                              17    4312
NP_056120                                                              16    5631
NP_055978                                                              16    5631
NP_443210                                                              16    5631
NP_872328                                                              16    5631
NP_001005527                                                           16    5631
XP_005267359                                                           16    5631
XP_005267358                                                           16    5631
XP_006720081                                                           16    5631
XP_006720080                                                           16    5631
NP_060909                                                              16    5631
NP_940857                                                              16    5631
NP_001767                                                              16    7355
NP_001157651                                                           16    7355
NP_001157650                                                           16    7355
NP_001091645                                                           16    7355
NP_542415                                                              16    7355
NP_542416                                                              16    7355
NP_542414                                                              16    7355
NP_006255                                                              16    7355
NP_001136089                                                           16    7355
NP_001185970                                                           16    7355
NP_001185971                                                           16    7355
NP_055954                                                              16    7355
NP_001185969                                                           16    7355
NP_001136091                                                           16    7355
XP_006718140                                                           16    7355
XP_006718139                                                           16    7355
XP_005263224                                                           16    7355
XP_006710543                                                           16    7355
XP_006710542                                                           16    7355
XP_006710541                                                           16    7355
NP_001136090                                                           16    7355
NP_001622                                                              16    7355
NP_071764                                                              16    7355
NP_060855                                                              15    9605
XP_005259159                                                           15    9605
XP_005267426                                                           15    9605
NP_689660                                                              15    9605
NP_065913                                                              15    9605
>NP_004963
          Length = 1132

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           CAKNILL R
Sbjct: 675 CAKNILLIR 683
>XP_005251512
          Length = 1132

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           CAKNILL R
Sbjct: 675 CAKNILLIR 683
>NP_002218
          Length = 1154

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CAKNILLFR 9
           C KN+LL R
Sbjct: 716 CTKNLLLAR 724
>XP_005270898
          Length = 1154

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CAKNILLFR 9
           C KN+LL R
Sbjct: 716 CTKNLLLAR 724
>XP_006710687
          Length = 1154

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CAKNILLFR 9
           C KN+LL R
Sbjct: 716 CTKNLLLAR 724
>NP_003322
          Length = 1187

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CAKNILLFR 9
           C +NILL R
Sbjct: 736 CGRNILLAR 744
>NP_001230175
          Length = 804

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CAKNILLF 8
           CAK  LLF
Sbjct: 323 CAKTYLLF 330
>NP_036466
          Length = 2058

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  CAKNILLFR 9
          CA+ I++FR
Sbjct: 27 CAEGIVVFR 35
>NP_001001976
          Length = 518

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 509 CSERMLLFR 517
>NP_001275663
          Length = 403

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 394 CSERMLLFR 402
>NP_001275664
          Length = 422

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 413 CSERMLLFR 421
>NP_001275665
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 502 CSERMLLFR 510
>NP_008972
          Length = 518

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 509 CSERMLLFR 517
>NP_071751
          Length = 736

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CAKNILLF 8
           CAK  LLF
Sbjct: 323 CAKTYLLF 330
>NP_001139761
          Length = 697

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CAKNILLF 8
           CAK  LLF
Sbjct: 323 CAKTYLLF 330
>XP_005258838
          Length = 563

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CAKNILLF 8
          C +NILL+
Sbjct: 68 CCQNILLY 75
>XP_005269518
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 526 CSERMLLFR 534
>XP_005269517
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 526 CSERMLLFR 534
>XP_005269516
          Length = 554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 545 CSERMLLFR 553
>XP_005269515
          Length = 561

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 552 CSERMLLFR 560
>XP_005269513
          Length = 578

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CAKNILLFR 9
           C++ +LLFR
Sbjct: 569 CSERMLLFR 577
>XP_006714538
          Length = 2035

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  CAKNILLFR 9
          CA+ I++FR
Sbjct: 27 CAEGIVVFR 35
>NP_775904
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CAKNILLF 8
          C +NILL+
Sbjct: 68 CCQNILLY 75
>NP_056120
          Length = 670

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  CAKNILL 7
          C KN+LL
Sbjct: 27 CRKNVLL 33
>NP_055978
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>NP_443210
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>NP_872328
          Length = 140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CAK++LL
Sbjct: 9  CAKSVLL 15
>NP_001005527
          Length = 140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CAK++LL
Sbjct: 9  CAKSVLL 15
>XP_005267359
          Length = 714

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>XP_005267358
          Length = 777

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>XP_006720081
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>XP_006720080
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  CAKNILL 7
          CA+NIL+
Sbjct: 33 CARNILV 39
>NP_060909
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   CAKNILL 7
           CA+NIL+
Sbjct: 284 CARNILV 290
>NP_940857
          Length = 5147

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    CAKNILLF 8
            CA+N+L++
Sbjct: 2425 CARNLLMW 2432
>NP_001767
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CAKNIL 6
          C+KNIL
Sbjct: 13 CSKNIL 18
>NP_001157651
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CAKNIL 6
          C+KNIL
Sbjct: 13 CSKNIL 18
>NP_001157650
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CAKNIL 6
          C+KNIL
Sbjct: 25 CSKNIL 30
>NP_001091645
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CAKNIL 6
          C+KNIL
Sbjct: 20 CSKNIL 25
>NP_542415
          Length = 2294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CAKNILLF 8
           C+K +L+F
Sbjct: 798 CSKGVLVF 805
>NP_542416
          Length = 2490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CAKNILLF 8
           C+K +L+F
Sbjct: 798 CSKGVLVF 805
>NP_542414
          Length = 2485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CAKNILLF 8
           C+K +L+F
Sbjct: 798 CSKGVLVF 805
>NP_006255
          Length = 2466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CAKNILLF 8
           C+K +L+F
Sbjct: 798 CSKGVLVF 805
>NP_001136089
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLFR 9
           +N+LLFR
Sbjct: 461 RNLLLFR 467
>NP_001185970
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLFR 9
           +N+LLFR
Sbjct: 476 RNLLLFR 482
>NP_001185971
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLFR 9
           +N+LLFR
Sbjct: 500 RNLLLFR 506
>NP_055954
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KNIL+
Sbjct: 290 CIKNILI 296
>NP_001185969
          Length = 704

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLFR 9
           +N+LLFR
Sbjct: 498 RNLLLFR 504
>NP_001136091
          Length = 658

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLFR 9
           +N+LLFR
Sbjct: 452 RNLLLFR 458
>XP_006718140
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CAKNIL 6
          C+KNIL
Sbjct: 25 CSKNIL 30
>XP_006718139
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CAKNIL 6
          C+KNIL
Sbjct: 25 CSKNIL 30
>XP_005263224
          Length = 2491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CAKNILLF 8
           C+K +L+F
Sbjct: 804 CSKGVLVF 811
>XP_006710543
          Length = 256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KNIL+
Sbjct: 191 CIKNILI 197
>XP_006710542
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KNIL+
Sbjct: 294 CIKNILI 300
>XP_006710541
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CAKNILL 7
           C KNIL+
Sbjct: 317 CIKNILI 323
>NP_001136090
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLFR 9
           +N+LLFR
Sbjct: 461 RNLLLFR 467
>NP_001622
          Length = 528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  AKNILLF 8
          AKN++LF
Sbjct: 52 AKNLILF 58
>NP_071764
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KNILLFR 9
           +N+LLFR
Sbjct: 461 RNLLLFR 467
>NP_060855
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AKNILLFR 9
           A+N LLFR
Sbjct: 183 ARNPLLFR 190
>XP_005259159
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CAKNILLF 8
          CAK  LLF
Sbjct: 51 CAKTGLLF 58
>XP_005267426
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CAKNILLF 8
          CAK  LLF
Sbjct: 37 CAKKGLLF 44
>NP_689660
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CAKNILLF 8
          CAK  LLF
Sbjct: 37 CAKKGLLF 44
>NP_065913
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CAKNILLF 8
          CAK  LLF
Sbjct: 51 CAKTGLLF 58
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.347    0.153    0.507 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,548
Number of extensions: 796
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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