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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              19     665
XP_005248564                                                           17    2528
NP_005900                                                              17    2528
NP_569118                                                              16    5631
NP_932065                                                              16    5631
NP_932064                                                              16    5631
XP_005254562                                                           16    5631
XP_006720650                                                           16    5631
XP_005254559                                                           16    5631
XP_006720649                                                           16    5631
XP_005254557                                                           16    5631
NP_059135                                                              16    7355
XP_005250505                                                           16    7355
XP_005250503                                                           16    7355
XP_006710560                                                           16    7355
XP_006710559                                                           16    7355
XP_006710558                                                           16    7355
XP_006710557                                                           16    7355
XP_006710556                                                           16    7355
XP_006710554                                                           16    7355
XP_005270723                                                           16    7355
XP_006710552                                                           16    7355
XP_006710551                                                           16    7355
XP_006710550                                                           16    7355
XP_006710549                                                           16    7355
XP_006710548                                                           16    7355
NP_003550                                                              15    9605
NP_005019                                                              15    9605
XP_006725428                                                           15    9605
XP_006725427                                                           15    9605
XP_006725426                                                           15    9605
XP_006722195                                                           15    9605
XP_006722194                                                           15    9605
XP_006722193                                                           15    9605
XP_006717513                                                           15    9605
NP_208382                                                              15    9605

>NP_005219
          Length = 1210

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AYVMAIVDN 9
           AYVMA VDN
Sbjct: 763 AYVMASVDN 771



>XP_005248564
          Length = 2342

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YVMAIVD 8
           YVMA+VD
Sbjct: 918 YVMAVVD 924



>NP_005900
          Length = 2468

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YVMAIVD 8
            YVMA+VD
Sbjct: 1044 YVMAVVD 1050



>NP_569118
          Length = 882

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YVMAIVDN 9
           YV+ ++DN
Sbjct: 681 YVVVVIDN 688



>NP_932065
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YVMAIVDN 9
           YV+ ++DN
Sbjct: 697 YVVVVIDN 704



>NP_932064
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YVMAIVDN 9
           YV+ ++DN
Sbjct: 697 YVVVVIDN 704



>XP_005254562
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YVMAIVDN 9
           YV+ ++DN
Sbjct: 278 YVVVVIDN 285



>XP_006720650
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YVMAIVDN 9
           YV+ ++DN
Sbjct: 697 YVVVVIDN 704



>XP_005254559
          Length = 829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YVMAIVDN 9
           YV+ ++DN
Sbjct: 697 YVVVVIDN 704



>XP_006720649
          Length = 855

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YVMAIVDN 9
           YV+ ++DN
Sbjct: 654 YVVVVIDN 661



>XP_005254557
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YVMAIVDN 9
           YV+ ++DN
Sbjct: 697 YVVVVIDN 704



>NP_059135
          Length = 854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AYVMAIVDN 9
           AYV  I+DN
Sbjct: 567 AYVRNILDN 575



>XP_005250505
          Length = 639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AYVMAIVDN 9
           AYV  I+DN
Sbjct: 352 AYVRNILDN 360



>XP_005250503
          Length = 806

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AYVMAIVDN 9
           AYV  I+DN
Sbjct: 567 AYVRNILDN 575



>XP_006710560
          Length = 1181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710559
          Length = 1188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710558
          Length = 1191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710557
          Length = 1191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710556
          Length = 1195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710554
          Length = 1421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_005270723
          Length = 1459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 604 AYLKAIVD 611



>XP_006710552
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710551
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710550
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710549
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>XP_006710548
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYVMAIVD 8
           AY+ AIVD
Sbjct: 609 AYLKAIVD 616



>NP_003550
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 363 YFMAIID 369



>NP_005019
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 353 YFMAIID 359



>XP_006725428
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 204 YFMAIID 210



>XP_006725427
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 299 YFMAIID 305



>XP_006725426
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 299 YFMAIID 305



>XP_006722195
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 204 YFMAIID 210



>XP_006722194
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 299 YFMAIID 305



>XP_006722193
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 299 YFMAIID 305



>XP_006717513
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YVMAIVD 8
           Y MAI+D
Sbjct: 302 YFMAIID 308



>NP_208382
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYVMAIVD 8
           AY M I+D
Sbjct: 381 AYAMKIID 388



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.135    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 284,970
Number of extensions: 348
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)